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Membrane Potential MCQ-WPS Office

The document discusses membrane potentials in neurons. It defines key terms like depolarization, action potential, and resting membrane potential. The Na+/K+ ATPase is identified as an antiport that contributes to the negative interior membrane potential through active transport of ions. At rest, potassium ions have the highest permeability in neurons, contributing to the negative resting membrane potential along with sodium, potassium, and chloride ion gradients established by the Na+/K+ pump. An action potential occurs when the membrane potential reaches threshold due to sufficient sodium ion influx through voltage-gated channels.

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459 views5 pages

Membrane Potential MCQ-WPS Office

The document discusses membrane potentials in neurons. It defines key terms like depolarization, action potential, and resting membrane potential. The Na+/K+ ATPase is identified as an antiport that contributes to the negative interior membrane potential through active transport of ions. At rest, potassium ions have the highest permeability in neurons, contributing to the negative resting membrane potential along with sodium, potassium, and chloride ion gradients established by the Na+/K+ pump. An action potential occurs when the membrane potential reaches threshold due to sufficient sodium ion influx through voltage-gated channels.

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© © All Rights Reserved
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Membrane Potentials

1. Na+-K+-ATPase is an example of a/an:

a) symport

b) uniport

c) biport

d) antiport

e) airport

Answer- D

2. Regarding membrane potential:

a) it is only found in nervous tissue

b) Na+/K+ pump does not contribute to the membrane potential

c) its magnitude does not change from tissue to tissue

d) the membrane potential is negative inside in relation to the outside

e) it is mainly caused by leaking Na+/K+ channels

Answer- D

3. Which of the following has the highest permeability in a resting nerve cell?

a) Na+

b) Cl–

c) I–

d) K+

Answer-D

4. Depolarization is when ___________ ions flow inside the neuron’s membrane.

a) Potassium

b) Sodium

c) Chloride
d) Magnesium

Answer- B

5. A neuron fires when _____________________

a) action potential is achieved

b) apoptosis is induced

c) re-stimulation occurs

d) stimulation ceases

Answer- A

6. Action potential can only flow in the forward direction.

a) True

b) False

Answer- A

7. A typical neuron has a resting membrane potential of about:

(A) +70 mV

(B) +70 V

(C) −70 mV

(D) −70 V

(E) All of the above are observed at rest

Correct answer: C

8. Which of the following is (are) directly responsible for the generation of the resting membrane
potential?

(A) Ionic gradients across the plasma membrane

(B) Permeability of the plasma membrane to various ions

(C) The Na+/K+ ATPase

(D) A and B only

(E) A, B, and C
Correct answer: D

9. The Na+/K+ ATPase is directly responsible for the establishment of the membrane potential.

True

False

Correct answer: False

10. By maintaining the Na+ and K+ concentration gradients, the Na+/K+ ATPase is responsible for
maintaining the membrane potential.

True

False

Correct answer: True

11. The following ion(s) is(are) the major contributor(s) to establishing the value of the resting
membrane potential in most cells.

(A) Na+

(B) K+

(C) Ca2+

(D) H+

(E) Cl−

Correct answer: A, B, and E

12. Which type of K+ channels share in resting membrane potential generation?

a. Leakage channel

b. Voltage gated channel

c. Calcium gated channels

d. Non selective ion channel

Answer- A
13. Which part of the neuron initiates the action potential?

a. Dendrites

b. Axon hillock

c. Cell body

d. Axon terminal

Answer- B

14. Resting membrane potential is created by all of the following membrane characteristics EXCEPT

a. High permeability to K+

b. Low permeability to Na+

c. High permeability to proteins

d. Opening of voltage gated sodium channels

Answer- C, D

15. In a cell membrane with resting membrane potential -60. If this potential becomes -90 there will be

a. Depolarization of 30 mv amplitude

b. Hyperpolarization with 30 mv amplitude

c. Local excitatory state

d. Generation of action potential with subthreshold stimulus

Answer- B

16. What is the main cation present intracellulary

a. K+

b. Na+

d. Ca++
d. Mg++

Answer- A

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