P'ceutical Analysis Mcqs Study Pharmacy
P'ceutical Analysis Mcqs Study Pharmacy
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DR. SUBHASH
cAM
TECINICAL PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
1. is used as primary standard for standardization of NaOH.
ha
A. Sodium carbonate
B. Sodium bicarbonate
ar
C. Sodium chloride
rm
D. Potassium dichromate
ma
Ans. B
ac
cy
A. 6.8-8.4
B. 1.2-2.8
y
8.3 11.0
C.
D. 4.2-6.3
Ans. C
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D. Random error
Ans. C
ud
B. Concentration
C. Solution
Ph
D. Concentrated solution
ha
Ans. A
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A. Arrhenius theory
m
B. Lewis theory
C. Bronsted theory
ac
ac
D. Lowry theory
Ans. A
y
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DR. SUBHASI1
THCINICAMC PHARMACEUTICAL ANALYSIS (BP102TTP)
Ph
Ans. A
ha
7. Substance that can be reversibly oxidized or reduced, having different distinct colour in
ar
the individual oxidized and reduced forms
rm
A. Redox indicators
ma
B. Redox potential
C. Redox number
ac
D. Redox state
cy
Ans. A
y
C. 0.5 M
D. 0.05 N
Ans. B
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A. Volume
B. pH
ud
C. Absorbance
D. Valency
Ans. D
y
A. Water
ha
B. Alcohol
ar
C. Acetic acid
D. None
rm
Ans. D
m
ac
A. Surface adsorption
B. Occlusion
y
C. Crystallization
D. Mechanical entrapment
Ans. D
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DR. SUBHASH
hCINICAL cAMPUS PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
B. Gravimetric titration
ha
C. Redox titration
D. Gasometric titration
ar
Ans. C
rm
ma
13. Potentiometry is type of, method.
A. Qualitative
ac
B. Chromatographic
cy
C. Classical
D. Electro-chemical1
y
Ans. D
St
15. used as titrant in non-aqueous titration.
ud
A. EDTA
B. Perchloric acid
C. Sodium nitrite
y
D. Silver nitrite
Ans. B
Ph
ha
A. Conductivity
B. Potential
rm
C. Temperature
m
D. Concentration
Ans. A
ac
ac
A. Sodium thiosulphate
B. Oxalic acid
C. Perchloric acid
D. None of these
Ans. A
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DR. SUBHASIT PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
18. The degree of agreement between measured value and accepted true value is
ha
A. Precision
ar
B. Accuracy
rm
C. Range
ma
D. Average deviation
Ans. A
ac
cy
19. Behavior of indicator is explained by . theory.
A. Chromospheres
y
B. lonic
C. Color
D. Resonance
Ans. D
20. pH is defined as
A. -log [OH-1
B. -log [H+
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C. pH +pOH
D. log pOH
ud
Ans. B
21. The titration carries out between KCl and AgNO3 is termed as titration.
y
A. Oxidation-Reduction
B. Precipitation
Ph
C. Acid-Base
ha
D. None of these
ar
Ans.B
rm
A. 0.1 M
B.0.1 N
ac
ac
C. Both A and B
D. 0.5 M
y
Ans. A
23. The number of gm-equivalent of the solute per liter of solution is known as
A. Normality
B. Molarity
C. Molality
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DR. SUBHASI1
TRCINICAL e PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
D. Mole fraction
ha
Ans.A
ar
24. The number of gm-mole of the solute per liter of solution is known as
rm
A. Normality
ma
B. Molarity
C. Molality
ac
D. Mole fraction
cy
Ans.B
y
26. The ratio of number of gm-mole ofa component to total number of gm-mole in mixture
St
St
or solution is known as
A. Normality
ud
B. Molarity
C. Molality
D. Mole fraction
y
Ans.D
Ph
A. Normality
ar
B. % weight by volume
C. Molality
rm
D. Mole fraction
m
Ans.B
ac
ac
28. The chemical reagent from which solution of required concentration can be prepared is
A. Secondary standard
y
B. Dilute solution
C. Concentrated solution
D. Primary standard
Ans.C
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DR. SUBHASH
cAM
TECINICAL PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
29. In strong acid - strong base titration, the pH of mixture at initial stage is find out by
ha
formula
A. PH=-log[H+1
ar
B. [H+1NaVa-NbVb/(Va + Vb)
rm
C. POH= -log[OH-I
D. [OH-]= NbVb - NaVa/ (Va+ Vb)
ma
Ans.A
ac
cy
30. In Standard solution which of the following is accurately known,
A. Normality, strength or % of chemicals
y
B. Volume
C. Pressure
D. Temperature
Ans.A
31. The process of adding known concentration until it complete the reaction with known
volume is called as
A. Titrant
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B. Analysis
C. Titration
ud
D. Titrend
Ans.C
y
B. Burette
ha
C. Instrument
ar
D. Indicator
Ans.D
rm
ac
B. Strength
C. Molecular Weight
y
D. Equivalence Weight
Ans.B
34. Exactly required concentration can be prepared from chemical reagent is called as
A. Primary standard
B. Secondary standard
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DR. SUBHAS1
TICINICAL PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
C. Both A &B
ha
D. None of this
Ans.A
ar
rm
ma
A. FeS04
B. Na2CO03
ac
C. NH4OH
cy
D. NaOH
Ans.B
y
St
37. A buffer solution can be formed by dissolving equal moles of
A. HF and NaF
ud
Ans. A
Ph
A. H30*
ar
B. AS04+
C. H3AS04
rm
D. H2ASO4*
m
Ans.B
ac
ac
39. Which of the following indicators has a transition point closest to the equivalence point
for the titration of a weak acid by a strong base?
y
A. Orange IV
B. Tliymol blue
C. Methyl orange
D. Bromcresol green
Ans.B
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DR. SUBHASI1
ECHNIC
PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
40. A solution of known concentration is the definition of a
ha
A. Buffer solution.
B. Neutral solution.
ar
C. Standard solution.
rm
D. Saturated solution.
ma
Ans.C
ac
cy
A. NH3
B. CO3 2
y
C. HSO3
D. H2BO3
Ans.B
St
D. Produces hydroxide ions in solution.
Ans.C
ud
ac
B. Phenol red
C. Thymol blue
y
D. Methyl violet
Ans.A
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DR. SUBHASH
cAMPUS
THCINICAL PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
C. Conduct electric current in solution
ha
ar
rm
ma
A. Adding a proton to the acid.
B. Adding an electron to the acid.
ac
cy
D. Removing an electron from the acid
Ans.C
y
St
48. Which of the folowing are general properties of bases in aqueous solution?
A. Feel slippery and increase H30+
ud
Ans.C
Ph
49. Pure sodium hydrogen phthalate is used to standardize a solution of NaOH for
ha
acid-base titration. What term is used to describe the sodium hydrogen phthalate?
ar
A. Titrant base
B. Standard buffer
rm
C. Equivalent base
m
D. Primary standard
Ans.D
ac
ac
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DR. SUBHASIT
TRCINICAcA PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
51. A Bronsted-Lowry acid is defined as a substance that
ha
A. releases H+ (aq)
B. releases OH-(aq)
ar
C. accepts proton in solution
rm
ma
Ans.D
ac
cy
[H3O+] is not present
[H3O+] is equal to [OH-|
y
St
D. A strong acid and its conjugate base.
Ans.B
ud
54. What do a chemical indicator and a buffer solution typically both contain?
A. A strong acid and its conjugate acid
y
Ans.D
ar
55. When performing a titration experiment, the indicator must always have
rm
ac
56. Which of the following is not a good use for an acid-base titration curve?
A. to determine the concentration of the base
B. to select a suitable indicator for the titration
C. to determine whether the acid is strong or weak
D. to select a suitable primary standard for the titration
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DR. SUBHASI1
THCINICALMCA PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
Ans.D
ha
57. Which of the following acids has the weakest conjugate base?
ar
A. HIO3
rm
B. HNO2
ma
C. H3P04
D.CH3COOH
ac
Ans.A
cy
58. Which of the followiing 1.0M salt solutions will be acidic?
y
A. NaNO3
B.NaHCO3
C. NaHS04
D. NaHPO4
Ans.C
St
B. Transition point.
C. Equivalence point.
ud
D. Stoichiometric point.
Ans.B
y
ac
B. releases OH (aq)
C. accepts a proton
y
D. donates a proton
Ans.D
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DR. SUBHASIT
CHNIC. PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
C. A strong acid and its conjugate acid.
ha
ar
rm
ma
A. OH-
B. PO4
ac
C. HPO4
cy
D. H3PO4
Ans.B
y
St
65. Non aqueous titration is carried out for
A. Water insoluble drug
ud
Ans. D
Ph
A. Chloroform
ar
B. Benzene
C. Both
rm
D. None
m
Ans. B
ac
ac
B. Hydrochloric acid
C. Nitric acid
D. All the above
Ans. D
68. Protophilic solvent is
A. Sodium hydroxide
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DR. SUBHASI1
TECNICAL
c PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
B. Lithium methoxide
ha
C. Sodium methoxide
D. All
ar
Ans. D
rm
ma
69. Which one is useful in non aqueous titration?
A. Leveling solvent
ac
B. Differentiating solvent
cy
C. Both
D. None
y
Ans. A
St
71. In the preparation of the 0.l (N) perchloric acid amotmt of acetic anhydride should be
ud
optimum. Why?
A. If added more quantity then amine drug may acetylate and causes erroneous result
B. If added less quantity then water may interfere with the titration,
y
Ans.B
ha
ar
B. Oxalic acid
m
ac
Ans.C
y
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DR. SUBHASIT
THCHNICALer PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
ha
ar
B. Colour of the solution is low
rm
C. Both
ma
D. None
Ans.C
ac
cy
75. Sodium Acetate, NaC2H302, is a water soluble salt that forms an aqueous solution that is
A. Acidic
y
B. Basic
C. Neutral
Ans.B
St
D. Metrifonate
Ans.D
ud
Ans.D
rm
ac
A. P.R
B. P,S
C. Q.R
D. P.Q
Ans.D
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DR. SUBHASH
THCINICAL CAMPUS PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
79. Principle involved in non aqueous titration of weakly basic drug
ha
ar
C. Proton donation from perchloric acid to acetie acid
rm
ma
Ans.D
ac
cy
A. Modified Volhard's method
B. Mohr's method
y
C. Fajan's method
D. None of the above
Ans.A
St
Ans.A
ud
C. Amperometric
D. Conductometric
Ph
Ans.A
ha
ar
B. Mohr's method
m
C. Volhard's method
D. All
ac
ac
Ans.A
y
84. Which method follows the principle of formation of coloured precipitate at the end point?
A. Fajan's method
B. Volhard's method
C. Modified Volhard's metlrod
D. All
Ans.D
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DR. SUBHASI1
TICINICAL A PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
ha
ar
B. Mohr's method
rm
C. Volhard's method
ma
D. None
Ans.B
ac
cy
86.Potassium chromate (K2Cr04) is used as an indicator in
A. Mohr's method
y
B. Volhard's method
C. Fajan's method
D. None
Ans.A
St
C. Methyl red
D. Ninhydrin
ud
Ans.A
A. Fajan's method
B. Mohr's method
Ph
C. Volhard's method
ha
D. None
ar
Ans. B
rm
89. EDTA has binding sites and therefore it is also called as multidentate ligand.
m
A. Six
B. Five
ac
ac
C. Four
D. Seven
y
Ans.C
90. agent forms the complex with the metal ions that are not required in the
estimation
A. Masking
B. Demasking
St
St
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DR.HCHNICAL
SUBHASIT
CA PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
C. Both
ha
Ans.B
ar
91. The endpoint for an EDTA titration is usually found by using a indicator
rm
A. Metallochromic
ma
B. Redox
C. Acid base
ac
D. All
cy
Ans.A
y
St
A. Salicylaldoxime
B. 8-hydroxy quinolilne
ud
C. EDTA
D. All
Ans.C
y
94.The complexometric titration where EDTA is used carried out at basic pH. Why?
Ph
Ans.D
m
ac
A. Sod. Sulphide
B. Oxalate
y
C. Thiocetanaide
D. All
Ans.C
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DR. SUBHASI1
cuNIC
PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
B. Arsenic
ha
C. Lead
D. All
ar
Ans.D
rm
ma
97. Indicator used in complexometric titration is
A. Erichrome black T
ac
E-Xylenolorange
cy
C. Mordant black II
D. All
y
Ans.D
98. Name the assay method for the drud calcium gluconate
A. Non aq titration
B. Acid base titaration
C. Complexometric
D. lodometric
Ans.C
St
St
99. Number of rings observed in the tetravalent ion EDTA complex
ud
A. 4
B. 5
C. 6
y
D. 3
Ans.B
Ph
ha
D. both a and b
Ans.B
ac
ac
101. In. analyte is separated from a solution of the sample as a precipitate and
y
St
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DR. SUBHASIT
THCHNICALe PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
ha
ar
B. Precipitation factor
rm
C. Electrogravimetry factor
ma
D. None of the above
Ans.A
ac
cy
103. Digestion of precipitate also known as
A. Ageing
y
B. Gravimetric factor
C. Co- precipitation
D. Ostwald ripening
Ans.D
St
C. Volt
D. None of the above
ud
Ans.B
A. A.C
B. D.C
Ph
C. Both A and B
ha
D. None of these
ar
Ans.A
rm
A. Conductivity
B. Molar conductance
ac
ac
C. Conductance Enhancers
D. None of the above
y
Ans.C
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DR. SUBHASI1
THCINICAcA PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
D. None of the above
ha
Ans.B
ar
108. is the conductance offered by 1 cm^ of an electrolytic solution
rm
A. Molar conductjince
ma
B. Conductance Enhancers
C. Specific conductance
ac
D. Specific Resistance
cy
Ans.C
y
St
A. Antimony electrode
B. Silver-silver electrode
ud
C. Calomel electrode
D. None of the above
Ans.A
y
A. PH
ha
B. PM
ar
C. Both a and b
D. None of the above
rm
Ans.B
m
112. Which of the following two are used reference electrodes in polentiometry?
ac
ac
P) Glass membrane
Q) Hg-calomel
y
R) Ag-silver chloride
S) lon selective
A)P.Q B)P,S C)Q.R D)P,R
Ans.C
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DR. SUBHASIT
c
TICINICAL PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
A. Indicator electrode
ha
B. Reference electrode
C. Secondary reference electrode
ar
D. Both A and b
rm
Ans.D
ma
113. electrode is employed as a secondary reference electrode
ac
A. Hydrogen electrode
cy
B. Droping Mercury Electrode
C. Calomel electrode
y
St
Ans.A
ud
C. Both A and B
D. None of the above
Ph
Ans.B
ha
ar
116. In polarography, when limiting current is achieved, one of the following process
takes place. Choose that.
rm
A-The rate of electron transfer just matches the rate of mass transfer
m
B. The rate of electron transfer is slower than the rate of mass transfer
C. The rate of electron transfer becomes independent of the rate of mass transfer
ac
ac
D. The rate of electron transfer far exceeds the rate of mass transfer
Ans.B
y
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DR. SUBHASH
c
TICINICAL PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
Ans.B
ha
ar
A, Diffusion current
rm
ma
C. Voltage
D. None of the above
ac
Ans.B
cy
119. Limiting current is sum of diffusion current and
y
A. Residual current
B. Faradic current
C. Migration current
D.Additional current
Ans.B
St
R Higher current
C Migration Currerrt
ud
D.Residual current
Ans.D
y
ac
B. Refractometry
C. Potentiometry
y
D. Conductometry
Ans.A
123. Sodium vapor lamp used in Polarlmeter emit light of wavelength (in Angstrom)
A. 5890 & 5896
B. 4368 & 4916
St
St
St
St
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DR. SUBHASIT
TECNICAL CA PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
C5770 & 5791
ha
ar
rm
ma
A. loss of hydrogen
B. loss of oxygen
ac
C. gain in hydrogen
cy
D. gain in electrons
Ans.A
y
St
126. Oxidizing agents
A. are mostly non-metals
ud
Ans.A
Ph
127. Upon oxidation of acidified potassium manganate (VI), the puiple color of
ha
Manganese
ar
A. stays
B. changes to pink
rm
C. becomes colorless
m
D. becomes blue
Ans.C
ac
ac
A. by taking oxygen
B. by giving electron
C. by taking hydrogen
D. Both A and B
Ans.D
St
St
St
St
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DR. SUBHAS1
THCINICAL CAMPUS PHARMACEUTICAL ANALYSIS (BP102TP)
Ph
129 Reduction involves
ha
A. loss of oxygen
B. gain in hydrogen
ar
C gain in oxygen
rm
D. loss of electrons
ma
Ans.A
ac
cy
A. potassium iodide
B. potassium manganate
y
C. potassium dichromate
D. bromine solutions
Ans.A
St
St
ud
y
Ph
ha
ar
rm
m
ac
ac
y
y
St
St