Tarun Sir

VEDANTU Biology By: Tarun Sir

Principle of Inheritance and Variations-2
DOPA PRIME AND MUTANT QUESTIONS
1. Mark the correct Statement - 7. Which of the following mutation is responsible for
(a) Body colour gene s sex -linked in drosophila cancer
(b) Eye colour gene is not sex linked in drosophila (a) Chromosomal aberration
(c) Heterogametic member in birds produce two (b) Polyploidy
type of sperm
(c) Aneuploidy (d) Point mutation
(d) Drone in honey bee produce sperm by meiosis

2. For ZZ/ZW type of sex determination mark the 8. Mutations are generally ……. And ……..
incorrect (a) beneficial and dominant
(a) peacock is example of this type (b) harmful and incompletely dominant
(b) Heterogametic member produce two type of egg (c) beneficial and condominant
(c) Male and female have equal number of (d) harmful and recessive
chromosome
(d) Sperm chromosomes determine the sex of
progeny 9. Mark the correct statement -
(a) Polyploidy viable in both plants and animals
3. Chromosome number may not be equal in (b) Trisomy is due to extra copy of more then one
(a) Two sperm in honey bee drone autosome in gamete
(b) Two sperm of grass hopper (c) Non-disjunction in anaphase II result in
(c) Two egg in birds
aneuploidy
(d) Two sperm produce by male drosophila
(d) Double trisomy in human can have 48
4. Point mutations are caused by chromosome in zygote
(a) substitution of base pair
(b) deletion of sugar 10 The plant which was popular by De Vries mutation
(c) insertion of sugar theory ?
(d) Substitution ,deletion and addition of one (a) Zea mays (b) Avena sativa
nucleotide
(c) Oenothera lamarkiana
5. Mark the correct statement (d) Eugenia aromaticum
(a) Gametes can be produce by mitosis or meiosis in
honey bee 11. In Sickle cell anaemia , mutation in DNA
replaced ……. Codon to ……… on mRNA
(b) Drosophila male produce sperm with one X-
(a) GGC to GAG (b) GAG to GUG
chromosome or without any X or Y chromosome
(c) GTG to CAC (d) CUC to GUG
(c) Always male is heterogametic in chromosomal
sex -determination 12. Transfer of genes from one chromosome to other
(d) Henking discovered that X-body in insect non homologous one is
oogenesis (a) interchange (b) deletion
(c) translocation (d) Point mutation
6. Mark the correct statement
(a) Male and female cockroach have unequal 13. Sometimes DNA and chromsomes replicate without
number of Autosomes the division of the nucleus resulting in the increase
(b) 50 percent sperm in grasshopper is without sex in somatic chromosme number. Such a change is
chromosome called …….. and artificaily induced by …….
(a) polyploidy and colchicine
(c) 50 percent ovum in grasshopper is without X-
(b) linkage and X-ray
chromosome
(c) Polyploidy and mustard gas
(d) all of above (d) crossing over and UV

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DOPA PRIME
 VEDANTU Biology By: Tarun Sir
Principle of Inheritance and Variations-2
DOPA PRIME AND MUTANT QUESTIONS
14. Polyploidy is naturally seen in 21. Sex linked characters have which one of the
(a) Endosperm following not feature ?
(b) Tapetum (a) Carrier female for colourblindness show 50
(d) honey bee percent son colourblind
(d) both 1 and 2 (b) Male never pass trait to son
(c) Female can pass trait to both son and daughter
15. A trisomic individual has a chromosome number … (d) male can be dominant or recessive for trait
and example
(a) 2n +1 and turner’s syndrome 22. Heterozygous female for Haemophilia show
(b) 2n + 3 and Edward syndrome (a) father is haemophilic
(c) 2n + 1 and down’s syndrome (b) Mother is heterozygous carrier
(d) 2n + 2 and kleinfelter’s syndrome (c) all son hemophilic
(d) Mother is homozygous normal and father also
16. If the haploid number of chromosomes is 20, what is normal
tetrasomic number ?
(a) 20 (b) 42 23. Colour blindness is a disease usually affecting man
(c) 30 (d) 44 but the factor for it is transmitted to the children
always by woman. This is because particular factor
17. If the haploid number of chromosomes in a plant is is located on
23, then the number of chromosomes in monosomic (a) X chromosome
is (b) Y chromosome
(a) 26 (b) 47 (c) Both X and Y chromosomes
(c) 22 (d) 45 (d) Autosome

18. Which one of the following is a not true 24. If a normal woman marries a colour blind man then
(a) Myotonic dystrophy is dominant trait all their
(b) colour blind daughter mother can be normal (a) Sons will be colour blind and daughter normal
(c) Carrier for sickle cell anemia can be male or (b) Daughters will be colour blind and sons normal
female as trati present on X-chromosome (c) Children will be normal
(d) Muscular dystrophy and Cystic fibrosis is inborn (d)all Children will be colour blind
error of metabolism
25. A colour blind daughter is born when
19. A genetic disease, which is never passed on from (a) Father is colour blind, mother is normal
father to son is (b) Mother is colour blind, father is normal
(a) X–chromosomal linked disease (c) Mother is carrier, father is normal
(b) Y–chromosomal linked disease (d) Mother is carrier, father is colour blind
(c) Autosomal linked disease
(d) Autosomal dominant 26. A human with thallesimia which is incorrect
(a) Has reduced rate of synthesis of globin chain
20. A hereditary sex linked disease in which the blood (b) In alpha-thalassemia two closely linked gene on
fails to clot in less time is called chromosme 11 is mutated
(a) haemophilia (c) In Beta- thallasemia one gene on chromosome
(b) anaemia 16 show mutation
(c) erythroblastosis foetalis (d) Thalassemia is chracterised by incorrect
(d) colour blindness functioning of alpha globin chain

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DOPA PRIME
 VEDANTU Biology By: Tarun Sir
Principle of Inheritance and Variations-2
DOPA PRIME AND MUTANT QUESTIONS
27. Select the incorrect statement with regard to (b) Abnormal sperm with extra X fuse with normal
haemophilia: ovum
(a) male with haemophilia trait on X-chromosome (c) Abnormal sperm with X and Y chromosome
is always viable fuse with normal ovum
(b) Single protein involved in the clotting of blood (d) Male with extra X-chromosome
is affected
(c) Female rarely show haemophilia
33. Y-chromosome is compulsory present in –
(d) It is a recessive disease on chromosome X
(a) Few Sperm of cockroach
28. Male and female not have equal number of (b) All Sperm of drosophila
chromosome in (c) Sperm result in Klinefelter’s syndrome
(a) Male with down syndrome and female with (d) Few sperm of birds
turner’s syndrome
(b) Male with haemophilia and female with sickle
cell anaemia 34. Thalassemia and sickle cell anaemia are caused
(c) Myotonic dystrophy in male and and Muscular due to a problem in globin molecule synthesis.
dystrophy in female Select the correct statement.
(d) Female with down’s syndrome and male with (a) Both are due to a quantitative defect in globin
kleinfelter’s syndrome chain synthesis.
(b) Thalassemia is due to less synthesis of globin
29. Mark the incorrect about phenylketonuria- molecules.
(a) Pleiotropic gene is mutated due to which inborn (c) Sickle cell anaemia is due to a quantitative
error of metabolism occur problem of globin molecules.
(b) Excess phenyalanine converted into ketone (d) Both are due to a qualitative defect in globin
bodies chain synthesis. (NEET 2017)
(c) Melanin synthesis decrease lead to mental
retardation 35. The genotypes of a husband and wife are I A I B
(d) Tyrosine synthesis retarded and I A i. Among the blood types of their children,
how many different genotypes and phenotypes are
30. Similarity between sickle cell anaemia and possible?
thalassemia is – (a) 3 genotypes; 4 phenotypes
(b) 4 genotypes; 3 phenotypes
(a) Qualitative disease
(c) 4 genotypes; 4 phenotypes
(b) Abnormal haemoglobin synthesis
(d) 3 genotypes; 3 phenotypes (NEET 2017)
(c) Mutation on Chromosome 16
(d) Carrier are normal in phenotype 36. A disease caused by an autosomal primary non
disjunction is
31. Which is not sterile – (a) Klinefelter’s syndrome
(a) Worker bee in honey bee (b) Turner’s syndrome
(b) Kleinfelter’s syndrome (c) sickle cell anaemia
(c) Turner’s syndrome (d) Down’s syndrome. (NEET 2017)
(d) Down’s syndrome
37. Among the following characters, which one was
not considered by Mendel in his experiments on
32. Kleinfelter’s syndrome not develop when –
pea?
(a) Abnormal ovum with extra X fuse with normal (a) TrichomesGlandular or nonglandular
sperm
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DOPA PRIME
 VEDANTU Biology By: Tarun Sir
Principle of Inheritance and Variations-2
DOPA PRIME AND MUTANT QUESTIONS
(b) SeedGreen or yellow 43. A tall true breeding garden pea plant is crossed
(c) PodInflated or constricted with a dwarf true breeding garden pea plant. When
(d) StemTall or dwarf (NEET 2017) the F 1 plants were selfed the resulting genotypes
were in the ratio of
38. Which one from those given below is the period (a) 3 : 1 : : Tall : Dwarf
for Mendel’s hybridisation experiments? (b) 3 : 1 : : Dwarf : Tall
(a) 1840-1850 (c) 1 : 2 : 1 : : Tall homozygous : Tall
(b) 1857-1869 heterozygous : Dwarf
(c) 1870-1877 (d) 1 : 2 : 1 : : Tall heterozygous : Tall
(d) 1856-1863 (NEET 2017) homozygous : Dwarf. (NEETI 2016)

39. The mechanism that causes a gene to move from 44. Match the terms in column I with their description
one linkage group to another is called in column II and choose the correct option.
(a) inversion (b) duplication Column I Column II
(c) translocation (d) crossingover. A. Dominance (i) Many genes govern a
(NEETII 2016) single character
B. Codominance (ii) In a heterozygous
40. If a colourblind man marries a woman who is organism only one
homozygous for normal colour vision, the allele expresses itself
probability of their son being colourblind is C. Pleiotropy (iii) In a heterozygous
(a) 0 (b) 0.5 organism both alleles
(c) 0.75 (d) 1. (NEETII2016) express themselves
fully
41. A cell at telophase stage is observed by a student D. Polygenic (iv) A single gene influences
in a plant brought from the field. He tells his inheritance many
teacher that this cell is not like other cells at characters
telophase stage. There is no formation of cell plate A B C D
and thus the cell is containing more number of (a) (iv) (i) (ii) (iii)
chromosomes as compared to other dividing cells. (b) (iv) (iii) (i) (ii)
This would result in (c) (ii) (i) (iv) (iii)
(a) somaclonal variation (d) (ii) (iii) (iv) (i) (NEETI 2016)
(b) polyteny (c) aneuploidy
(d) polyploidy. (NEETI 2016) 45. In a test cross involving F 1 dihybrid flies, more
Parental type offspring were produced than the
42. Pick out the correct statements. Recombinant type offspring. This indicates
(1) Haemophilia is a sex linked recessive disease. (a) the two genes are linked and present on the
(2) Down’s syndrome is due to aneuploidy. same chromosome
(3) Phenylketonuria is an autosomal recessive gene (b) both of the characters are controlled by more
disorder. than one gene
(4) Sickle cell anaemia is an X linked recessive (c) the two genes are located on two different
gene disorder. chromosomes
(a) (1), (3) and (4) are correct. (d) chromosomes failed to separate during
(b) (1), (2) and (3) are correct. meiosis. (NEETI 2016)
(c) (1) and (4) are correct.
(d) (2) and (4) are correct. (NEETI 2016)

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DOPA PRIME
 VEDANTU Biology By: Tarun Sir
Principle of Inheritance and Variations-2
DOPA PRIME AND MUTANT QUESTIONS
46. Which of the following most appropriately (a) Autosomal recessive
describes haemophilia? (b) Xlinked dominant
(a) Chromosomal disorder (c) Autosomal dominant
(b) Dominant gene disorder (d) Xlinked recessive (2015)
(c) Recessive gene disorder
(d) Xlinked recessive gene disorder 52. The term “linkage” was coined by
(NEETI 2016) (a) G. Mendel (b) W. Sutton
47. A gene showing codominance has (c) T.H. Morgan (d) T. Boveri. (2015)
(a) alleles that are recessive to each other
(b) both alleles independently expressed in the 53. The movement of a gene from one linkage group
heterozygote to another is called
(c) one allele dominant on the other (a) translocation (b) crossing over
(d) alleles tightly linked on the same chromosome. (c) inversion (d) duplication.
(2015) (2015 Cancelled)

48. In his classic experiments on pea plants, Mendel 54. Alleles are
did not use (a) different molecular forms of a gene
(a) seed shape (b) flower position (b) heterozygotes
(c) seed colour (d) pod length. (2015) (c) different phenotype
(d) true breeding homozygotes.
49. A colour blind man marries a woman with normal (2015 Cancelled)
sight who has no history of colour blindness in her
family. What is the probability of their grandson 55. Multiple alleles are present
being colour blind ? (a) at the same locus of the chromosome
(a) Nil (b) 0.25 (b) on nonsister chromatids
(c) 0.5 (d) 1 (2015) (c) on different chromosomes
(d) at different loci on the same chromosome.
50. A pleiotropic gene (2015 Cancelled)
(a) controls a trait only in combination with
another gene 56. A man with blood group ‘A’ marries a woman
(b) controls multiple traits in an individual with blood group ‘B’. What are all the possible
(c) is expressed only in primitive plants blood groups of their offsprings?
(d) is a gene evolved during Pliocene. (2015) (a) A, B, AB and O
(b) O only
51. In the following human pedigree, the filled (c) A and B only
symbols represent the affected individuals. Identify (d) A, B and AB only
the type of given pedigree. (2015 Cancelled)

57. How many pairs of contrasting characters in pea

plants were studied by Mendel in his experiments?
(a) Eight
(b) Seven
(c) Five
(d) Six
(2015 Cancelled)

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DOPA PRIME
 VEDANTU Biology By: Tarun Sir
Principle of Inheritance and Variations-2
DOPA PRIME AND MUTANT QUESTIONS
58. An abnormal human baby with ‘XXX’ sex 64. If both parents are carriers for thalassaemia, which
chromosomes was born due to is an autosomal recessive disorder, what are the
(a) fusion of two ova and one sperm chances of pregnancy resulting in an affected
(b) fusion of two sperms and one ovum child?
(c) formation of abnormal sperms in the father (a) 25% (b) 100%
(d) formation of abnormal ova in the mother. (c) No chance (d) 50% (NEET 2013)
(2015 Cancelled)
65. If two persons with ‘AB’ blood group marry and
59. Fruit colour in squash is an example of have sufficiently large number of children, these
(a) recessive epistasis children could be classified as ‘A’ blood group:
(b) dominant epistasis ‘AB’ blood group : ‘B’ blood group in 1 : 2 : 1
(c) complementary genes ratio. Modern technique of protein electrophoresis
(d) inhibitory genes. (2014) reveals presence of both ‘A’ and ‘B’ type proteins
in ‘AB’ blood group individuals. This in an
60. A man whose father was colour blind marries a example of
woman who had a colour blind mother and normal (a) partial dominance
father. What percentage of male children of this (b) complete dominance
couple will be colour blind? (c) codominance
(a) 25% (d) incomplete dominance. (NEET 2013)
(b) 0%
(c) 50% 66. Which idea is depicted by a cross in which the F 1
(d) 75% (2014) generation resembles both the parents?
(a) Inheritance of one gene
61. A human female with Turner’s syndrome (b) Codominance
(a) has 45 chromosomes with XO (c) Incomplete dominance
(b) has one additional X chromosome (d) Complete dominance (NEET 2013)
(c) exhibits male characters
(d) is able to produce children with normal 67. Which one is the incorrect statement with regard to
husband. (2014) the importance of pedigree analysis?
(a) It confirms that DNA is the carrier of genetic
62. Select the incorrect statement with regard to information.
haemophilia. (b) It helps to understand whether the trait in
(a) It is a dominant disease. question is dominant or recessive.
(b) A single protein involved in the clotting of (c) It confirms that the trait is linked to one of
blood is affected. the autosome.
(c) It is a sexlinked disease. (d) It helps to trace the inheritance of a specific
(d) It is a recessive disease. (NEET 2013) trait. (Karnataka NEET 2013)

63. Which of the following cannot be detected in a 68. Down’s syndrome in humans is due to
developing foetus by amniocentesis? (a) three ‘X’ chromosomes
(a) Down’s syndrome (b) three copies of chromosome 21
(b) Jaundice (c) monosomy
(c) Klinefelter’s syndrome (d) two ‘Y’ chromosomes.
(d) Sex of the foetus (NEET 2013) (Karnataka NEET 2013)

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DOPA PRIME
 VEDANTU Biology By: Tarun Sir
Principle of Inheritance and Variations-2
DOPA PRIME AND MUTANT QUESTIONS
69. A normal visioned man whose father was 73. Which one of the following conditions correctly
colourblind, marries a woman whose father was describes the manner of determining the sex?
also colourblind. They have their first child as a (a) Homozygous sex chromosomes (ZZ) determine
daughter. What are the chances that this child female sex in birds.
would be colourblind? (b) XO type of sex chromosomes determine male
(a) 100% sex in grasshopper.
(b) Zero percent (c) XO condition in humans as found in Turner’s
(c) 25% syndrome, determines female sex.
(d) 50% (2012) (d) Homozygous sex chromosomes (XX) produce
male in Drosophila. (2011)
70. F2 generation in a Mendelian cross showed that
both genotypic and phenotypic ratios are same as 1 74. Which one of the following conditions of the
: 2 : 1. It represents a case of zygotic cell would lead to the birth of a normal
(a) codominance human female child?
(b) dihybrid cross (a) Two X chromosomes
(c) monohybrid cross with complete dominance (b) Only one Y chromosome
(d) monohybrid cross with incomplete dominance. (c) Only one X chromosome
(2012) (d) One X and one Y chromosome
(Mains 2011)
71. Represented below is the inheritance pattern of a
certain type of trait in humans. Which one of the 75. Test cross in plants or in Drosophila involves
following conditions could be an example of this crossing
pattern? (a) between two genotypes with recessive trait
(b) between two F 1 hybrids
(c) the F 1 hybrid with a double recessive genotype
(d) between two genotypes with dominant trait.
(Mains 2011)

76. Which one of the following symbols and its

representation, used in human pedigree analysis is
correct?

(a) Phenylketonuria
(b) Sickle cell anaemia
(c) Haemophilia
(d) Thalassemia (Mains 2012)
77. ABO blood groups in humans are controlled by the
72. A test cross is carried out to gene I. It has three alleles I A , I B and i. Since there
(a) determine the genotype of a plant at F2 are three different alleles, six different genotypes
(b) predict whether two traits are linked are possible. How many phenotypes can occur?
(c) assess the number of alleles of a gene (a) Three
(d) determine whether two species or varieties will (b) One
breed successfully. (Mains 2012) (c) Four
(d) Two (2010)

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DOPA PRIME
 VEDANTU Biology By: Tarun Sir
Principle of Inheritance and Variations-2
DOPA PRIME AND MUTANT QUESTIONS
78. Select the correct statement from the ones given 83. A cross in which an organism showing a dominant
below with respect to dihybrid cross. phenotype is crossed with the recessive parent in
(a) Tightly linked genes on the same chromosomes order to know its genotype is called
show higher recombinations. (a) monohybrid cross
(b) Genes far apart on the same chromosome show (b) back cross
very few recombinations.
(c) test cross
(c) Genes loosely linked on the same chromosome
show similar recombinations. (d) dihybrid cross.
(d) Tightly linked genes on the same chromosome (Mains 2010)
show very few recombinations. (2010) 84. In Antirrhinum two plants with pink flowers were
hybridized. The F1 plants produced red, pink and
79. The genotype of a plant showing the dominant white flowers in the proportion of 1 red, 2 pink and
phenotype can be determined by 1 white. What could be the genotype of the two
(a) test cross (b) dihybrid cross
plants used for hybridization? Red flower colour is
(c) pedigree analysis (d) back cross. (2010)
determined by RR, and white by rr genes?
80. Which one of the following cannot be explained on (a) rrrr
the basis of Mendel’s law of dominance? (b) RR
(a) The discrete unit controlling a particular (c) Rr
character is called a factor. (d) rr (Mains 2010)
(b) Out of one pair of factors one is dominant, and
the other recessive. 85. Select the incorrect statement from the following.
(c) Alleles do not show any blending and both the (a) Galactosemia is an inborn error of metabolism.
characters recover as such in F2 generation. (b) Small population size results in random genetic
(d) Factors occur in pairs. (2010) drift in a population.
(c) Baldness is a sex limited trait.
81. ABO blood grouping is controlled by gene I which (d) Linkage is an exception to the principle of
has three alleles and show codominance. There are independent assortment in heredity. (2009)
six genotypes. How many phenotypes in all are
possible? 86. Sickle cell anaemia is
(a) Six (b) Three (a) caused by substitution of valine by glutamic
(c) Four (d) Five (Mains 2010) acid in the beta globin chain of haemoglobin
(b) caused by a change in a single base pair of
82. Study the pedigree chart of a certain family given DNA
below and select the correct conclusion which can (c) characterized by elongated sickle like RBCs
be drawn for the character. with a nucleus
(d) an autosomal linked dominant trait. (2009)

87. The genetic defect–adenosine deaminase (ADA)

deficiency may be cured permanently by
(a) The female parent is heterozygous. (a) administering adenosine deaminase activators
(b) The parents could not have had a normal (b) introducing bone marrow cells producing ADA
daughter for this character. into cells at early embryonic stages
(c) The trait under study could not be colour (c) enzyme replacement therapy
blindness. (d) periodic infusion of genetically engineered
(d) The male parent is homozygous dominant. lymphocytes having functional ADA cDNA.
(Mains 2010) (2009)

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DOPA PRIME
 VEDANTU Biology By: Tarun Sir
Principle of Inheritance and Variations-2
DOPA PRIME AND MUTANT QUESTIONS
88. The most popularly known blood grouping is the 92. In pea plants, yellow seeds are dominant to green.
ABO grouping. It is named ABO and not ABC, If a heterozygous yellow seeded plant is crossed
because “O” in it refers to having with a green seeded plant, what ratio of yellow and
(a) overdominance of this type on the genes for A green seeded plants would you expect in F 1
and B types generation?
(b) one antibody only either anti A or anti B on the (a) 9 : 1 (b) 1 : 3
RBCs (c) 3 : 1 (d) 50 : 50. (2007)
(c) no antigens A and B on RBCs
(d) other antigens besides A and B on RBCs. 93. Inheritance of skin colour in humans is an example
(2009) of
(a) point mutation
89. Study the pedigree chart given below. What does it (b) polygenic inheritance
show? (c) codominance
(d) chromosomal aberration. (2007)

94. A common test to find the genotype of a hybrid is

by
(a) crossing of one F2 progeny with female parent
(b) studying the sexual behaviour of F1 progenies
(a) Inheritance of a condition like phenylketonuria (c) crossing of one F1 progeny with male parent
as an autosomal recessive trait. (d) crossing of one F2 progeny with male parent.
(b) The pedigree chart is wrong as this is not (2007)
possible.
(c) Inheritance of a recessive sexlinked disease 95. Test cross involves
like haemophilia. (a) crossing between two genotypes with dominant
(d) Inheritance of a sexlinked inborn error of trait
metabolism like phenylketonuria. (b) crossing between two genotypes with recessive
(2009) trait
(c) crossing between two F 1 hybrids
90. Which one of the following conditions in humans (d) crossing the F 1 hybrid with a double recessive
is correctly matched with its chromosomal genotype. (2006)
abnormality/linkage?
(a) Erythro blastosis foetalis Xlinked 96. Both sickle cell anaemia and Huntington’s chorea
(b) Down’s syndrome 44 autosomes + XO are
(a) virus- related diseases
(c) Klinefelter’s syndrome 44 autosomes + XXY (b) bacteria- related diseases
(d) Colour blindness Y linked (2008) (c) congenital disorders
(d) pollutant - induced disorders. (2006)
91. A human male produces sperms with the
genotypes AB, Ab, aB, and ab pertaining to two 97. If a colour blind woman marries a normal visioned
diallelic characters in equal proportions. What is man, their sons will be
the corresponding genotype of this person? (a) all colour blind
(a) AaBB (b) all normal visioned
(b) AABb (c) one -half colour blind and one- half normal
(c) AABB (d) three- fourths colour blind and one- fourth
(d) AaBb. (2007) normal. (2006)

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DOPA PRIME
 VEDANTU Biology By: Tarun Sir
Principle of Inheritance and Variations-2
DOPA PRIME AND MUTANT QUESTIONS
98. In Mendel’s experiments with garden pea, round 103. A man and a woman, who do not show any
seed shape (RR) was dominant over wrinkled apparent signs of a certain inherited disease, have
seeds (rr), yellow cotyledon (YY) was dominant seven children (2 daughters and 5 sons). Three of
over green cotyledon (yy). What are the expected the sons suffer from the given disease but none of
phenotypes in the F2 generation of the cross RRYY the daughters affected. Which of the following
× rryy? mode of inheritance do you suggest for this
(a) Round seeds with yellow cotyledons, and disease?
wrinkled seeds with yellow cotyledons (a) Sex-linked dominant
(b) Only round seeds with green cotyledons (b) Sex-linked recessive
(c) Only wrinkled seeds with yellow cotyledons (c) Sex-limited recessive
(d) Only wrinkled seeds with green cotyledons (d) Autosomal dominant (2005)
(2006)
104. Haemophilia is more commonly seen in human
99. How many different kinds of gametes will be males than in human females because
produced by a plant having the genotype (a) a greater proportion of girls die in infancy
AABbCC? (b) this disease is due to a Y-linked recessive
(a) Two mutation
(b) Three (c) this disease is due to an X-linked recessive
(c) Four mutation
(d) Nine (2006) (d) this disease is due to an X-linked dominant
mutation. (2005)
100. Phenotype of an organism is the result of
(a) genotype and environment interactions 105. In a plant, red fruit (R) is dominant over yellow
(b) mutations and linkages fruit (r) and tallness (T) is dominant over shortness
(c) cytoplasmic effects and nutrition (t). If a plant with RRTt genotype is crossed with a
(d) environmental changes and sexual dimorphism. plant that is rrtt,
(2006) (a) 25% will be tall with red fruit
(b) 50% will be tall with red fruit
101. Which one of the following is an example of (c) 75% will be tall with red fruit
polygenic inheritance? (d) all the offspring will be tall with red fruit.
(a) Skin colour in humans (2004)
(b) Flower colour in Mirabilis jalapa
(c) Production of male honey bee 106. A male human is heterozygous for autosomal
(d) Pod shape in garden pea (2006) genes A and B and is also hemizygous for
haemophilic gene h. What proportion of his sperms
102. In order to find out the different types of gametes will be abh?
produced by a pea plant having the genotype AaBb (a) 1/8 (b) 1/32
it should be crossed to a plant with the genotype (c) 1/16 (d) 1/4 (2004)
(a) AABB
(b) AaBb 107. Lack of independent assortment of two genes A
(c) aabb and B in fruit fly Drosophila is due to
(d) aaBB. (2005) (a) repulsion
(b) recombination
(c) linkage
(d) crossing over. (2004)

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DOPA PRIME
 VEDANTU Biology By: Tarun Sir
Principle of Inheritance and Variations-2
DOPA PRIME AND MUTANT QUESTIONS
108. One of the parents of a cross has a mutation in its 114. In Drosophila, the sex is determined by
mitochondria. In that cross, that parent is taken as a (a) the ratio of number of X-chromosome to the
male. During segregation of F2 progenies that sets of autosomes
mutation is found in (b) X and Y chromosomes
(a) one-third of the progenies (c) the ratio of pairs of X-chromosomes to the pairs
(b) none of the progenies of autosomes
(c) all the progenies (d) whether the egg is fertilized or develops
(d) fifty percent of the progenies. (2004) parthenogenetically. (2003)

109. A normal woman, whose father was colourblind is 115. On selfing a plant of F 1 generation with genotype
married to a normal man. The sons would be “AABbCC”, the genotypic ratio in F 2 generation
(a) 75% colourblind will be
(b) 50% colourblind (a) 3 : 1
(c) all normal (b) 1 : 1
(d) all colourblind. (2004) (c) 9 : 3 : 3 : 1
(d) 27 : 9 : 9 : 9 : 3 : 3 : 3 : 1. (2002)
110. Which one of the following traits of garden pea
studied by Mendel was a recessive feature? 116. A gene is said to be dominant if
(a) Axial flower position (a) it expresses it’s effect only in homozygous state
(b) Green seed colour (b) it expresses it’s effect only in heterozygous
(c) Green pod colour condition
(d) Round seed shape (2003) (c) it expresses it’s effect both in homozygous and
heterozygous condition.
111. The genes controlling the seven pea characters (d) it never expresses it’s effect in any condition.
studied by Mendel are now known to be located on (2002)
how many different chromosomes?
(a) Seven 117. A diseased man marries a normal woman. They get
(b) Six three daughters and five sons. All the daughters
(c) Five were diseased and sons were normal.
(d) Four (2003) The gene of this disease is
(a) sex linked dominant
112. Pattern baldness, moustaches and beard in human (b) sex linked recessive
males are examples of (c) sex limited character
(a) sex linked traits (d) autosomal dominant. (2002)
(b) sex limited traits
(c) sex influenced traits 118. A and B genes are linked. What shall be genotype
(d) sex determining traits. (2003 of progeny in a cross between AB/ab and ab/ab?
(a) AAbb and aabb
113. Down’s syndrome is caused by an extra copy of (b) AaBb and aabb
chromosome number 21. What percentage of (c) AABB and aabb
offspring produced by an affected mother and a (d) None of the above (2001)
normal father would be affected by this disorder?
(a) 100 % (b) 75 % 119. Number of Barr bodies in XXXX female is
(c) 50 % (d) 25 % (2003) (a) 1 (b) 2
(c) 3 (d) 4. (2001)

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DOPA PRIME
 VEDANTU Biology By: Tarun Sir
Principle of Inheritance and Variations-2
DOPA PRIME AND MUTANT QUESTIONS
120. Male XX and female XY sometime occur due to 126. A person whose father is colour blind marries a
(a) deletion lady whose mother is daughter of a colour blind
(b) transfer of segments in X and Y chromosome man. Their children will be
(c) aneuploidy (a) all sons colour blind
(d) hormonal imbalance. (2001) (b) some daughter normal and some colour blind
(c) all colour blind
121. Due to the cross between TTRr × ttrr the resultant (d) all daughters normal. (1996)
progenies show what percent of tall, red flowered
plants 127. The colour blindness is more likely to occur in
(a) 50% males than in females because
(b) 75% (a) the Y-chromosome of males have the genes
(c) 25% for distinguishing colours
(d) 100%. (2000) (b) genes for characters are located on the sex-
chromosomes
122. According to Mendelism, which character shows (c) the trait is dominant in males and recessive
dominance? in females
(a) Terminal position of flower (d) none of the above. (1994)
(b) Green colour in seed coat
(c) Wrinkled seeds 128. Mr. Kapoor has Bb autosomal gene pair and d
(d) Green pod colour (2000) allele sexlinked. What shall be proportion of Bd in
sperms?
123. Haemophilic man marries a normal woman. Their (a) Zero (b) 1/2
offsprings will be (c) 1/4 (d) 1/8 (1993)
(a) all haemophilic
(b) all boys haemophilic 129. Of a normal couple, half the sons are haemophiliac
(c) all girls haemophilic while half the daughters are carriers. The gene is
(d) all normal. (1999) located on
(a) X-chromosome of father
124. Crossing over in diploid organism is responsible (b) Y-chromosome of father
for (c) one X-chromosome of mother
(a) segregation of alleles (d) both the X-chromosomes of mother. (1993)
(b) recombination of linked alleles
(c) dominance of genes 130. Segregation of Mendelian factors (no linkage, no
(d) linkage between genes. (1998) crossing over) occurs during
(a) anaphase I (b) anaphase II
125. Albinism is known to be due to an autosomal (c) diplotene (d) metaphase I.
recessive mutation. The first child of a couple with (1992)
normal skin pigmentation was an albino. What is
the probability that their second child will also be 131. A man of A-blood group marries a women of AB -
an albino? blood group. Which type of progeny would
(a) 50% indicate that man is heterozygous A?
(b) 75% (a) AB
(c) 100% (b) A
(d) 25% (1998) (c) O
(d) B (1991)

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DOPA PRIME
 VEDANTU Biology By: Tarun Sir
Principle of Inheritance and Variations-2
DOPA PRIME AND MUTANT QUESTIONS
132. The contrasting pairs of factors in Mendelian 134. Blue eye colour is recessive to brown eye colour.
crosses are called A brown eyed man whose mother was blue eyed
(a) multiple alleles marries a blue-eyed women. The children will be
(b) allelomorphs (a) both blue eyed and brown eyed 1 : 1
(c) alloloci (b) all brown eyed
(d) paramorphs. (1991) (c) all blue eyed
(d) blue eyed and brown eyed 3 : 1. (1991)
133. First geneticist/father of genetics was
(a) De Vries (b) Mendel
(c) Darwin (d) Morgan. (1991)

Answer Key

1. (a) 28. (a) 56. (a) 84. (c) 112. (c)

2. (d) 29. (c) 57. (b) 85. (c) 113. (c)
3. (b) 30. (b) 58. (d) 86. (b) 114. (c)
4. (d) 31. (d) 59. (b) 87. (b) 115. (a)
5. (a) 32. (b) 60. (c) 88. (c) 116. (c)
6. (b) 33. (c) 61. (a) 89. (a) 117. (a)
7. (a) 34. (b) 62. (a) 90. (c) 118. (b)
8. (d) 35. (b) 63. (b) 91. (d) 119. (c)
9. (d) 36. (d) 64. (a) 92. (d) 120. (b)
10 (c) 37. (a) 65. (c) 93. (b) 121. (a)
11. (b) 38. (d) 66. (b) 94. (c) 122. (d)
12. (c) 39. (c) 67. (a) 95. (d) 123. (d)
13. (a) 40. (a) 68. (b) 96. (c) 124. (b)
14. (d) 41. (d) 69. (b) 97. (a) 125. (d)
15. (c) 42. (b) 70. (d) 98. (a) 126. (d)
16. (b) 43. (c) 71. (c) 99. (a) 127. (b)
17. (d) 44. (d) 72. (a) 100. (a) 128. (c)
18. (c) 45. (a) 73. (b) 101. (a) 129. (c)
19. (a) 46. (d) 74. (a) 102. (c) 130. (a)
20. (a) 47. (b) 75. (c) 103. (b) 131. (d)
21. (d) 48. (d) 76. (a) 104. (c) 132. (b)
49. (b) 77. (c) 105. (b)
22. (b) 133. (b)
50. (b) 78. (d) 106. (a)
23. (a) 134. (a)
51. (a) 79. (a) 107. (c)
24. (c)
52. (c) 80. (c) 108. (b)
25. (d)
53. (a) 81. (c) 109. (b)
26. (d) 54. (a) 82. (a) 110. (b)
27. (a) 55. (a) 83. (c) 111. (d)

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DOPA PRIME