Lesson 1 - The Cell Theory
Lesson 1 - The Cell Theory
General Biology 1
Ericko P. Alegria, LPT
The Cell Theory
What is cell?
The cell is the basic unit of all living organisms. It
is the smallest structure that is able to carry out
the basic functions of life.
The Cell Theory
Robert Hooke
In 1665, he was able
to observe in a piece
of cork specimen
structures which
appears as tiny
compartments
similar to small
rooms that are fitted
to each other.
The Cell Theory
Anton Van
Leeuwenhoek
In 1676, published
his observations on
tiny living organisms
which he named
animalcules.
The Cell Theory
Mid-19th century
Traditionallybelief on the theory of spontaneous
generation which supposed that living things may
arise from non-living matter.
Louis Pasteur’s experiment disproved that
theory.
The Cell Theory
Robert Brown
In 1831, he was able
to compare diverse
kinds of plant
specimens
They are all
composed of cell,
and inside the cell is
a dark dense spot
called nucleus.
The Cell Theory
Matthias Schleiden
In 1838, he
concluded that all
plant parts are made
of cells.
The Cell Theory
Theodore Schwann
In 1839, he stated
that all animal
tissues are
composed of cells.
The Cell theory
Rudolf Virchow
In1858, he
concluded that all
cells come from pre-
existing cells.
The Cell Theory
A cell is made up of
Organelles (mini
organs), structures with
a membrane that
performs a variety of
functions such protein
production, storage of
materials, harvesting
energy and digestion of
substance, and among
others.
Cell Organelles
Cell Membrane
Itconsists of a
bilayer of
phospholipid with
integral (embedded)
and peripheral
(attached) proteins,
as well as enzymes,
receptor proteins,
and glycoproteins.
Cell Organelles
Cell Membrane
Lipid molecules can
move literally across
the membrane
together with the
irregularity arranged
proteins (mosaic),
therefore referred to
as Fluid Mosaic.
Cell Organelles
Cytoplasm
Composed of water
with dissolved
substances such as
salt and protein.
Itis responsible for
the fluid nature of
the cell’s internal
environment and
that which allows the
organelles to
suspend
Cell Organelle
Nucleus
The control center of
the cell.
Itis enclosed in a
double membrane
which selectively
permits certain
materials or
compounds to exit.
Cell Organelles
Chromatin Strand
A long strand of DNA
molecule is present
which wounds
around histone
proteins to form
helical structure.
Cell Organelles
Nucleolus
Itis where the
subunits of the
ribosome are
assembled and
include the synthesis
and maturation of
ribosomal RNA for
release in the
cytoplasm where
protein synthesis
occurs.
Cell Organelles
Endomembrane System
It consists of membranes and organelles that
work together to modify, package, and transport
lipids and proteins.
Cell Organelles
Endoplasmic Reticulum
(ER)
Itis a membranous
system of
interconnected
tubules which served
as the transport
system of the cell.
Cell Organelles
Endoplasmic Reticulum
(ER)
Itis composed of
two types based on
the presence or
absence of attached
ribosomes:
Rough
Endoplasmic
Reticulum (Rough
ER)
Smooth
Cell Organelles
Rough Endoplasmic
Reticulum (Rough ER)
Itappears grainy in
structure in the
electron micrograph,
thus name as rough.
Itresponsible in the
production of
secretory proteins
such as
glycoproteins.
Cell Organelles
Smooth Endoplasmic
Reticulum (Smooth ER)
It lacks ribosomes on
its outer surface.
Various metabolic
processes such as
metabolism of
carbohydrates, lipid
synthesis, and
detoxification of
drugs, chemicals,
and poisons are
performed in this
Cell Organelles
Vacuole
Itis one organelle
that is larger in
plants than in the
animal cells.
Ithas the ability to
enlarge as plant cells
absorb water.
Cell Organelles
Central Vacuole
(Tonoplast)
Itserves as the main
compartment for
storing essential
organic and
inorganic
compounds.
It is also a disposal
site for substances
that are needed by
the cell or that could
Cell Organelles
Lysosome
Itis an exclusive
organelle for animal
cells which carries out
intracellular digestion.
Itcontains hydrolytic
enzymes that are used
to digest all kinds of
macromolecules.
Cell Organelles
Mitochondrion (pl.
Mitochondia)
Itis the powerhouse
of the cell where
cellular respiration
takes place.
Adenosine
Triphosphate (ATP) is
the usable form of
energy for the cell to
perform its
functions.
Cell Organelles
Chloroplast
Is only found in the
plant cell and other
photosynthetic
eukaryotic
organisms; it is the
site for food
production.
Cell Organelles
Cytoskeleton
Itestablishes the
form cell and holds
the organelles in
place.
Itis composed of the
following:
Microfilaments
Microtubules
Intermediate
filaments
Cell Organelles
Microfilamets
Made up of actin
molecules which fine
fibers of
approximately 7-8
nm diameter.
Cell Organelles
Microtubules
They are composed
of tubulin forming a
hollow cylinder of 25
nm in diameter.
Cell Organelles
Intermediate filaments
They are around 8-
10 nm that make it
“intermediate” in
size.
They are rigid and
resist stretching.
Cell Types
General Biology 1
Ericko P. Alegria, LPT
Cell Types
Prokaryotic Cells
DNA is found in a region called nucleoid that has
no membrane.
The posses cytoplasm.
A semi-rigid wall is present and membrane-bound
organelles with specialized functions are absent
They are unicellular (single- celled) which include
the members of kingdom Eubacteria and
Archaebacteria
Theyare microscopic ranging from 1-10 µm in
diameter.
Cell Types
Eukaryotic Cells
Chromosomes are enclosed inside the nucleus.
They posses cytoplasm.
They are bigger with 10-100 µm in diameter.
Kingdom Protista, fungi, plantae and animalia are
the members of eukaryotic living things.