PRODUCT SPECIFICATIONS

Thermo Scientific Nicolet iS10 FTIR spectrometer

Infrared spectroscopy with confidence

Designed for laboratories with quality control, analytical

services or forensic duties, the Thermo Scientific™
Nicolet™ iS™10 FTIR spectrometer delivers the highest
confidence in the verification and identification of
materials. The Nicolet iS10 spectrometer provides
maximum assurance in its ability to sample and solve
challenging problems with a minimal investment in time.

The Nicolet iS10 FTIR spectrometer includes features

that validate the instrumental performance, verify the
quality of materials, create SOPs and suitability tests,
identify unknowns or mixtures, and quantify mixture
ingredients. The Nicolet iS10 spectrometer has been
developed especially for the material characterization
process, from loading sample information to final report. Designed for ease of use
Users of any skill level can operate the system, with many The Nicolet iS10 FTIR spectrometer has been designed
tasks completed with one click. for the ease of use and reliability required by laboratories
with heavy workloads.

Specifications you can trust • Easy to access, rechargeable desiccants and built-in
The Nicolet iS10 FTIR spectrometer is built to inspire humidity indicator
a high level of customer confidence. All instrument • Integrated scan button and SOP builder, for simple
specifications are factory verified to ensure each unit user interface, consistency and productivity
meets our rigorous quality standards. Specifications are: • Thermo Scientific™ Nicolet™ Smart Accessory™
technology for simple accessory exchange and
• Certified on each instrument before leaving the experimental conditions setup
manufacturing floor
• Material verification package with standard and high
• Representative of actual instrument performance, sensitivity correlation algorithm, to fit variability of
not “typical” or “achievable” tested materials
• Not reliant on artificial data processing or manipulations • Innovative multi-component analysis allows identification
of principal ingredients of mixtures, enabling every
laboratory to troubleshoot contamination problems
with confidence
Optical system Humidity and vapor protection
The sealed and desiccated optical unit protects the • Sealed and desiccated optical bench with protective
instrument from humidity and solvent vapors. A self- coating on KBr windows
compensating, dynamically aligned interferometer • Rechargeable desiccant cartridges
removes any tilt and shear scanning error, automatically • Humidity indicator
tunes the instrument for best throughput and provides • Multi-zone pressure system for optional purge
analysis speed for real time survey or screening.
Frequency calibration
Diamond turned, pinned-in-place, alignment-free optics
• HeNe laser tube
guarantee long life system performance with minimum
maintenance. • Does not require software optimization or calibration

Spectrometer performance verification

Detectors
• Integrated validation wheel with NG-11 and NIST
• Fast recovery deuterated triglycine sulfate (DTGS)
traceable polystyrene film standards, serialized
detector
• System Performance Verification (SPV) software and
• Liquid-nitrogen-cooled mercury cadmium telluride
programmable tasks interface
(MCT) detector
External beam options
Source
• Optional external beam for infrared microscopes or
• Mid-infrared Ever-Glo; user replaceable from sample
external Thermo Scientific™ Nicolet™ iZ™10 FTIR module
compartment
• The Nicolet iZ10 FTIR module can be used with the
• Tungsten/halogen; user replaceable from sample
NIR integrating sphere (InGaAs detector), TGA interface
compartment
or any other mid-infrared accessories, and can be
Beamsplitter equipped with a DTGS or MCT detector
• KBr/Ge mid-infrared optimized
Quality and low cost of ownership—guaranteed
• XT-KBr/Ge extended range mid-infrared
• Fully protected optics to ensure maximum resistance
from chemical vapors and humidity
• Five-year warranty on diamond
crystal of the Thermo
Scientific™ Smart iTX™ ATR
accessory, optimized for the
Nicolet iS10 spectrometer
The optical efficiency, diamond
turned mirrors and dynamically
aligned interferometer of the Nicolet
Optional tungsten halogen iS10 provide speed, sensitivity,
source and desiccant precision and accuracy
compartment are easily
accessible Electronics
The Nicolet iS10 source • 24-bit analog to digital converter; digital signal
is mounted in the sample
processor for spectrometer monitoring and software
compartment allowing quick
and easy optimization of data integrated controls
collection in the mid-near or • Integrated scan button panel including LED control
infrared region
status for source, laser and interferometer
• USB 2.0 high-speed bidirectional communication
• Smart Accessory automatic recognition, parameter
setting and spectral quality monitoring
• Enhanced synchronization protocol continuously
monitors power supply, laser, source and detector
 Nicolet iS10 FTIR spectrometer
equipped with Smart iTX ATR accessory
and integrating sphere mounted in the
Nicolet iZ10 external module.

Enhanced analytical power and productivity Nicolet iS10 FTIR spectrometer

• Measure samples directly through vials with the Thermo Scientific OMNIC software suite
integrating sphere conveniently mounted in the Nicolet • Collect, set-up parameters and spectral preview, customizable toolbar and
iZ10 FTIR module menu options
• Characterize materials quickly and easily by switching • Display capabilities: Zoom, roll, stack, overlay, offset and interactive display
to TGA/IR interface installed in the Nicolet iZ10 FTIR mode tools
module • Data processing: Baseline correction (automatic and manual), smooth,
• Achieve high throughput screening by powder and blank and straight line, first and second derivative, curve fitting, spectral
math, subtract (manual and automatic)
liquid auto samplers
• Data conversion and corrections: Kubelka Munk, Kramers Kronig,
• Identify unknowns with the power of Thermo Scientific™
Photoacoustic, ATR correction including settings for crystal material,
OMNIC™ Specta™ software, which includes a 9,000 reflections, angle and sample refractive index
spectra database and innovative multi-component
• Spectral Search: High-resolution library generation, customizable
search routines information fields, single or multi-region search, library management,
standard libraries (1400 spectra)
Designed for instrument qualification
• Spectral peak picking, audit trails history log, multi-format converters for
System Performance Verification (SPV) is a powerful J-camp DX other vendors’ spectral files and user libraries
tool to ensure that the spectrometer is performing as • Spectral groups statistical analysis: Variance, average, and range
expected, day after day. SPV includes hardware and
• Peak analysis tools: Peak area, peak height, cursor, peak text annotation
software to test the instrument against the ASTM E1421
• Automatic atmospheric suppression (no standards needed) to remove H2O
method by using Shott NG-11 and NIST traceable and CO2 interferences
standards, contained in a built-in motorized wheel.
• SOP builder (task-driven compiler) to execute through Integrated Scan Button
The Nicolet iS10 system verification is programmable panel (Thermo Scientific™ OMNIC™ Macros\Basic™ compiler and reader)
and can be set for:
• T hermo Scientific™ QCheck™ for spectrum-to-spectrum or spectrum-to-
multiple spectra QC/QA verification; includes correlation, high sensitivity
• Daily performance verification
compare, customizable pass/fail threshold
• System suitability
• Quantitative and discriminant analysis package including:
• Validation standards expiration date – Beer-Lambert calibration and prediction (peak height or area integration)
• Scheduling preventative maintenance visits – Classical Least Squares calibration and prediction
– Discriminant analysis, Partial Least Squares (PLS) and Principal
Component Analysis (PCR) prediction

• Infrared spectral interpretation tool and online guide

The Nicolet iS10 provides efficient tools to

identify pure compounds and mixtures with
confidence and ease of use. OMNIC Specta
software includes innovative ways to manage
your results and provide answers with the
confidence you need.
 Validation options for FDA, EP or JP regulated
industries
• Thermo Scientific™ ValPro™ System Qualification
specifically addresses DQ/IQ/OQ (Design, Installation,
and Operational Qualification). Provides “objective
evidence” to regulators and ISO auditors, showing that
their Thermo Scientific system
has been properly selected,
implemented, and verified for
use in their process.
• Digital and electronic signature,
21 CFR Part 11 compliance
package
5-second collection time polymer film spectra with and without
automatic atmospheric suppression (expanded region). Other specifications
• Dimensions (W × D × H): 550 × 570 × 250 mm
(21.7 × 22.4 × 9.8 in.)
Smart Accessory compatibility
• Weight: 39 Kg (86 lb)
The Nicolet iS10 spectrometer is compatible with our
extensive line of Smart Accessories specialized for • Regulatory Approvals: CE, ETL
quantitative analysis, reaction studies, surface and thin • Warranty:
film measurements. ––One year on complete system
––Ten years on modulator
• Simple accessory exchange and experiment setup
––Five years on laser
• Maintain proper experimental conditions and pre-set
parameters ––Two years on source
• Automatic performance verification ––Five years on Smart iTX (optional) diamond

Performance specifications*
• Spectral range:
––7800–350 cm-1 optimized, mid-infrared KBr
beamsplitter
––11000–375 cm-1 XT KBr extended range
mid-infrared optics
• Signal-to-noise: 1 minute: 50,000:1 (peak to peak)
• Wavenumber precision: 0.0008 cm-1 at 2000 cm-1
• Wavenumber accuracy: 0.02 cm-1 at 2000 cm-1
• Collection speed: variable from 0.16 cm/sec to
2.5 cm/sec; suitable to slow responsivity (PAS) and
high-sensitivity (MCT) detectors
• Maximum speed: 40 spectra per second at 16 cm-1
resolution, individually collected and stored
• Spectral resolution: better than 0.4 cm-1
• Ordinate linearity (ASTM E1421):
<0.1 %T deviation from 0.0 %T

* Factory verified: Specifications are certified on every instrument before it leaves the
manufacturing facility.

Find out more at w ww.thermofisher.com/iS10

©2008-2017 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific
and its subsidiaries. Specifications, terms and pricing are subject to change. Not all products are available in all countries.
Please consult your local sales representative for details. PS51503_E 02/17M