This document summarizes several common sexually transmitted infections (STIs):
1. Chlamydia is the most common bacterial STI and can cause pelvic inflammatory disease, ectopic pregnancy, and infertility if left untreated. Treatment involves antibiotic therapy.
2. Gonorrhea is caused by Neisseria gonorrhoeae and can lead to pelvic inflammatory disease, ectopic pregnancy, and infertility. It is treated with antibiotic therapy.
3. Syphilis is caused by Treponema pallidum and can cause severe damage to internal organs if untreated. It is diagnosed through blood tests and treated with penicillin.
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STI&STD
This document summarizes several common sexually transmitted infections (STIs):
1. Chlamydia is the most common bacterial STI and can cause pelvic inflammatory disease, ectopic pregnancy, and infertility if left untreated. Treatment involves antibiotic therapy.
2. Gonorrhea is caused by Neisseria gonorrhoeae and can lead to pelvic inflammatory disease, ectopic pregnancy, and infertility. It is treated with antibiotic therapy.
3. Syphilis is caused by Treponema pallidum and can cause severe damage to internal organs if untreated. It is diagnosed through blood tests and treated with penicillin.
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SEXUALLY TRANSMITTED INFECTIONS Instruct the client in the importance of
Also known as venereal diseases rescreening because reinfection can occur as
Diverse group of infections spread through the client nears term. sexual activity with an infected person Ensure that the sexual partner is treated. RISK FACTORS e. Complications 1. Having unprotected sex. Sterility 2. Having sexual contact with multiple partners. Premature and stillbirths 3. Having a history of STIs. Infant pneumonia and eye infections leading to 4. Anyone forced to have sexual intercourse or sexual blindness activity 5. Misuse of alcohol or use of recreational drugs. 6. Injecting drugs. B. GONORRHEA 7. Being young. a. Description and Pathophysiology Gonorrhea is an infection caused by Neisseria A. CHLAMYDIA gonorrhoeae, which causes inflammation a. Description and Pathophysiology of the mucous membranes of the genital and Most common and fast-spreading bacterial urinary tracts. STD Transmission of the organism is by sexual Sexually transmitted pathogen associated with intercourse an increased risk for premature birth, stillbirth, Infection may be transmitted to the newborn’s neonatal conjunctivitis, and newborn eyes during delivery, causing blindness chlamydial pneumonia (ophthalmia neonatorum- develops 2 to 5 days Can cause salpingitis, pelvic abscesses, ectopic after birth) pregnancy, chronic pelvic pain, and infertility Incubation period: 2-3 weeks for males; Incubation period: 2 to 10 days usually no symptoms (female) b. Assessment Causative agent: Chlamydia trachomatis,invades the reproductive Usually asymptomatic structures causing tissue irritation. If untreated, Whitish or yellowish vaginal/penile discharge it can cause sterility in infected women; can Urinary frequency transmit to infants during birth; and can spread Painful urination to eyes by autoinoculation (self-transmission lower abdominal pain to other area of the body. Painful bowel elimination with purulent rectal b. Assessment discharge (anal infection) Usually asymptomatic Sore throat (pharynx infection) Bleeding between periods or after coitus c. Diagnostic Procedures Mucoid or purulent cervical discharge Gram staining Dysuria and pelvic pain Culture of cervical and urethral smear (confirmatory) c. Diagnostic Procedure: culture for Chlamydia d. Management trachomatis Medical Management d. Management Medications -antibiotic therapy Medical Management Drug of Choice: Doycycline and azithromycin Medications- antibiotic therapy Nursing Management Drug of choice: Doxycycline and azithromycin Obtain a vaginal culture during the initial Nursing Management prenatal examination to screen for gonorrhea; the culture may be repeated during the third Screen the client to determine whether she is trimester in high-risk clients. high risk; a vaginal culture is indicated for all pregnant clients if the client is in a high-risk Instruct the client that treatment of her partner group or if infants from previous pregnancies is necessary if infection is present. have developed neonatal conjunctivitis or pneumonia. Administer crede’s prophylaxis after birth (as to repeat the test at 36 weeks’ gestation part of NB care) because the disease may be acquired after the initial visit (for Pregnant women) Administer antibiotics as prescribed C. SYPHILIS Instruct the client that treatment of her partner a. Description and Pathophysiology is necessary if infection is present and for Syphilis is a chronic infectious disease caused follow-up by the organism Treponema pallidum. Transmission is by physical contact with e. Complications: syphilitic lesions, which usually are found on 1. Severe damage to nervous system and other organs the skin, mucous membranes of the mouth, or (after many years) genitals, and through placental transmission 2. Heart disease (after 5th month of gestation) 3. Brain damage and severe illness or death (newborn) The infection may cause abortion or premature labor and is passed to the fetus after the fourth D. HERPES INFECTION month of pregnancy as congenital syphilis. a. Description and Pathophysiology Incubation period: 10 days to 3 months, Increases the risk for cervical cancer average: 21 days Transmission: direct contact with oral or b. Assessment (per stage) genital secretions from an infected person during active stage, sexual contact during Primary Stage (Most infectious stage) periods of asymptomatic viral shedding, or Appearance of ulcerative, painless lesions autoinoculation (chancre) produced by spirochetes at point of It can also be transmitted during delivery entry into the body (mother- child transmission) Caused by herpes simplex virus type 2, known Secondary Stage (Highly infectious stage) as genital herpes Appearance of lesions about 6 weeks to 6 The virus remains dormant in the ganglia of months after primary stage; located anywhere nerves causing recurring of symptoms on the skin and mucous membranes Generalized lymphadenopathy b. Assessment 1. Single or multiple vesicles (may rupture in 1 to 3 Tertiary Stage (Entrance of spirochetes into days) internal organs, causing permanent damage) 2. Painful and reddened ulcers Symptoms occur 10 to 30 years after untreated 3. Swelling of inguinal lymph nodes primary lesion Invasion of central nervous 4. Flu- like symptoms system, causing meningitis, ataxia, general 5. Headache paresis, and progressive mental deterioration Deleterious effects on aortic valve and aorta c. Management Medical Management c. Diagnostic Procedure 1. Medications- antiviral medications (acyclovir, 1. Rapid Plasma Reagin (RPR) - screening test valacyclovir) 2. Venereal Disease Research Laboratory (VDRL) Nursing Management 3. Fluorescent Treponema Antibody Absorption Test 1. Administer medications as prescribed (FTA- ABS) - confirmatory test 2. Instruct the client that treatment of her partner is Note: Follow up exam: 3,6, 12 months after initial necessary if infection is present treatment d. Complications: Cervical Cancer d. Management Medical Management 1. Medications - antibiotic therapy E. VENERAL WARTS Drug of choice: Pen G a. Description and Pathophysiology Nursing Management Also called as condylomas Obtain a serum test (Venereal Disease Causative Agent: human papilloma virus Research Laboratory or rapid plasma reagin) (HPV) for syphilis on the first prenatal visit; prepare Transmission: Transmitted via sexual contact \ i. genital- genital, Associated with premature labor and birth ii. genital- anal, b. Assessment iii. genital- oral; Client complains of “fishy odor” to vaginal iv. autoinoculation secretions b. Assessment increased odor after intercourse. Single or cluster, painless soft fleshy growth c. Diagnostic Procedure (genitalia, cervix, vagina, perineum, anus, Microscopic examination of vaginal secretions throat, mouth) identifies the infection. c. Management d. Management Medical/Surgical Management Medical Management 1. Medications- Podofilox cream 1. Medications - anti protozoal 2. Surgery- Metronidazole (Flagyl) • excision, Nursing Management • cauterization, 1. Sexual partner may need to be treated. • cryosurgery 2. Administer medications as ordered Nursing Management 1. Administer medications as ordered H. Vaginal candidiasis 2. Assist for surgery a. Description and Pathophysiology 3. Encourage annual Pap (Papanicolaou) smear. Candida albicans is the most common 4. Sexual contact should be avoided until lesions causative organism. are healed (condoms reduce transmission). Predisposing factors o use of antibiotics, o diabetes mellitus, F. TRICHOMONIASIS o obesity. diagnosed by : identifying spores of Candida a. Description an Pathophysiology albicans. Trichomoniasis is caused by Trichomonas b. Assessment vaginalis and is transmitted via sexual contact. Infection is associated with premature rupture Vulvar and vaginal pruritus of the membranes and postpartum White, lumpy, cottage cheese–like discharge endometritis. from vagina Transmission: contact with web objects c. Management (towels, wash clothes, douching equipment) Medical Management Incubation period: 4-20 days, ave: 7 days 1. Medications -antifungal vaginal preparation such as b. Assessment miconazole (Monistat) 1. Yellowish to greenish, frothy, mucopurulent, C2. Nursing Management copious, malodorous vaginal discharge 1. Sitz bath to relieve extensive irritation and swelling 2. Inflammation and itching of vulva, vagina, or both 2. Sexual partner may need to be treated may occur 3. Painful urination 4. Clear penile discharge c. Diagnostic Procedures 1. Microscopic slide of discharge- 2. Culture test Note: A normal saline wet smear of vaginal secretions indicates the presence of protozoa. d. Management - antibiotics (metronidazole)
G. BACTERIAL VAGINOSIS
a. Description and Pathophysiology
Caused by Haemophilus vaginalis (Gardnerella vaginalis) HUMAN IMMUNODEFICIENCY VIRUS (HIV) CD T- cell <200 mm3 AND ACQUIRED IMMUNODEFICIENCY Development of more severe opportunistic SYNDROME (AIDS) infection or cancer (Pneumonia and Kaposi’s Sarcoma) A. Definition and Pathophysiology Skin lesions that occur primarily in individuals HIV is transmitted through blood; blood with a compromised immune system products; and other bodily fluids, such as Assessment urine, semen, and vaginal secretions; the virus is also transmitted through exposure to Kaposi’s sarcoma is a slow-growing tumor infected secretions during birth and through that appears as raised, oblong, purplish, breast milk. reddish brown lesions; may be tender or nontender. HIV is the causative agent of AIDS. Organ involvement includes the lymph nodes, AIDS is a viral disease caused by human airways or lungs, or any part of the immunodeficiency virus (HIV), which gastrointestinal tract from the mouth to anus destroys T cells, thereby increasing susceptibility to infection and malignancy C. Diagnostic Procedures The syndrome is manifested clinically by opportunistic infection and unusual 1. ELISA (enzyme-linked immunosorbent neoplasms. assay) - screening test The disease has a long incubation period, 2. Western Blot and IFA (immunofluorescence sometimes 10 years or longer. assay) - confirmatory test Manifestations may not appear until late in the 3. CD 4 T- cells monitoring infection Causative agent: HIV 1, HIV 2, RNA D. Management Retrovirus Medical Management B. Assessment (per stage) 1. Medications- Anti retroviral a. Non-nucleoside reverse transcriptase inhibitors 1. Primary Infection (6 weeks to 6 months) (NNRTIs) turn off a protein needed by HIV to make Fever copies of itself. Examples include efavirenz (Sustiva), Headache rilpivirine (Edurant) and doravirine (Pifeltro). Muscle aches and joint pain b. Nucleoside or nucleotide reverse transcriptase Rash inhibitors (NRTIs) are faulty versions of the building Sore throat and painful mouth sores blocks that HIV needs to make copies of itself. Swollen lymph glands, mainly on the neck Examples include abacavir (Ziagen), tenofovir Diarrhea (Viread), emtricitabine (Emtriva), lamivudine (Epivir) Weight loss and zidovudine (Retrovir). Combination drugs also are Cough available, such as emtricitabine/tenofovir (Truvada) Night sweats and emtricitabine/tenofovir alafenamide (Descovy). c. Protease inhibitors (PIs) inactivate HIV protease, 2. Clinical latent infection (Chronic HIV)/ another protein that HIV needs to make copies of Asymptomatic Stage itself. Examples include atazanavir (Reyataz), darunavir (Prezista) and lopinavir/ritonavir (Kaletra). In this stage of infection, HIV is still present in d. Integrase inhibitors work by disabling a protein the body and in white blood cells. However, called integrase, which HIV uses to insert its genetic many people may not have any symptoms or material into CD4 T cells. Examples include infections during this time. bictegravir sodium/emtricitabine/tenofovir alafenamide CD4 T-cell count >500 mm3 fumar (Biktarvy), raltegravir (Isentress) and Symptomatic HIV dolutegravir (Tivicay). e. Entry or fusion inhibitors block HIV's entry into CD4 T- Cells between 200-499 mm3 CD4 T cells. Examples include enfuvirtide (Fuzeon) Unexplained or persistent diarrhea and fever and maraviroc (Selzentry). Presence of Opportunistic infections (TB, oral Candidiasis) Progression to AIDS Nursing Management 1. Provide respiratory support. 2. Administer oxygen and respiratory treatments as prescribed. 3. Provide psychosocial support as needed. 4. Maintain fluid and electrolyte balance. 5. Monitor for signs of infection. 6. Prevent the spread of infection. 7. Initiate standard and other necessary precautions. 8. Provide comfort as necessary. 9. Provide meticulous skin care.
HEALTH INSTRUCTIONS TO CLIENTS TO
PREVENT STI’S 1. Abstain. 2. Stay with one uninfected partner. 3. Wait and test. 4. Get vaccinated. 5. Use condoms and dental dams consistently and correctly. 6. Don't drink alcohol excessively or use drugs. 7. Communicate. 8. Consider male circumcision 9. Consider pre- exposure prophylaxis (PrEP).
Synonyms Causative Agents Incubatiob Period Mode of Transmission Signs and Symptoms Period of Communicability Diagnostic Test Medical Management Nursing Management Complications