Name: ________________________

Cell Biology Foundation

Class: ________________________

Date: ________________________

Time: 297 minutes

Marks: 294 marks

Comments:
Q1.
Figure 1 shows an animal cell.

Figure 1

© alex-mit/iStock/Thinkstock

(a) What is structure A?

Tick one box.

Cell membrane

Cell wall

Chromosome

Cytoplasm

(1)

(b) What is structure B?

Tick one box.

Chloroplast

Mitochondria

Nucleus

Vacuole

(1)

(c) Figure 2 shows a sperm cell.

 Figure 2

Describe how a sperm cell is adapted to carry out its function.

___________________________________________________________________

___________________________________________________________________
(1)

(d) Substances can move into and out of cells by three processes.

The diagrams show the concentration of different substances inside and outside a
root hair cell.

How would each substance move into the root hair cell?

Draw one line from each root hair cell to the correct process.

Root hair cell Process

(2)
(Total 5 marks)

Q2.
The figure below shows a scale drawing of one type of cell in blood.
 (a) Use the scale to determine the width of the cell.

Give your answer to the nearest micrometre.

___________________________________________________________________

___________________________________________________________________

Width of cell = _________________ micrometres

(1)

(b) Complete the table below.

Part of the blood Function

Carries oxygen around the

body

Protects the body against

infection

Plasma
(3)

(c) Platelets are fragments of cells.

Platelets help the blood to clot.

Suggest what might happen if the blood did not clot.

___________________________________________________________________

___________________________________________________________________
(1)
(Total 5 marks)

Q3.
Substances can move into cells and out of cells.
(a) Draw a ring around the correct answer to complete each sentence.

active transport.

Water moves into cells and out of cells by osmosis.

reabsorption.

freely permeable

The water moves through a non-permeable membrane.

partially permeable
(2)

(b) Students put plant cells into two different strengths of sugar solutions, A and B.

The diagram below shows what the cells looked like after 1 hour.

Cell in Cell in
sugar solution A sugar solution B
(after 1 hour) (after 1 hour)

(i) Describe two ways in which the cell in sugar solution B is different from the
cell in sugar solution A.

1. ____________________________________________________________

______________________________________________________________

2. ____________________________________________________________

______________________________________________________________
(2)

(ii) A student put red blood cells into water.

Suggest what would happen to the cells.

______________________________________________________________

______________________________________________________________

______________________________________________________________
(1)

(c) In the human body, glucose is absorbed into the blood from the small intestine.
 The small intestine contains many villi.

Which two of the following help the absorption of glucose in the small intestine?

Tick ( ) two boxes.

Villi have a cell wall.

Villi are covered in thick mucus.

Villi give the small intestine a large surface area.

Villi have many blood capillaries.

(2)
(Total 7 marks)

Q4.
The diagram shows some of the stages in IVF (in vitro fertilisation).

(a) Use words from the box to name structures A, B, C and D.

egg embryo fertilised egg ovary sperm

Structure A ____________________________

Structure B ____________________________

Structure C ____________________________

Structure D ____________________________
(4)

(b) What do doctors do next with structure D?

___________________________________________________________________
 ___________________________________________________________________

___________________________________________________________________

___________________________________________________________________
(2)

(c) The table gives statistics for an IVF clinic.

Age of women treated

Below 35 35 – 37 38 – 39 40 – 42
years years years years

Number of women treated 414 207 106 53

Number of women who

90 43 17 1
produced one baby

Number of women who

24 8 4 1
produced twins

Number of women who

1 0 0 0
produced triplets

(i) About what proportion of the treated women aged 35 – 37 years produced one
or more babies?

Draw a ring around your answer.

one quarter one third half

(1)

(ii) This clinic does not give IVF treatment to women over 42 years of age.

Use data from the table to explain why.

______________________________________________________________

______________________________________________________________

______________________________________________________________

______________________________________________________________
(2)

(iii) The committee which regulates IVF treatment now advises that only one
embryo is used in each treatment.

Suggest one reason for this.

______________________________________________________________
 ______________________________________________________________
(1)
(Total 10 marks)

Q5.
Substances can move into and out of cells.

(a) (i) How does oxygen move into and out of cells?

Draw a ring around one answer.

diffusion digestion photosynthesis

(1)

(ii) Diagram 1 shows the percentage concentration of oxygen in three cells, A, B

and C.

Diagram 1

Oxygen can move from cell to cell.

Into which cell, A, B or C, will oxygen move the fastest?

(1)

(b) (i) How does water move into and out of cells?

Draw a ring around one answer.

breathing osmosis respiration

(1)

(ii) Differences in the concentration of sugars in cells cause water to move into or
out of cells at different rates.

Diagram 2 shows three different cells, P, Q and R.

The information shows the percentage concentration of sugar solution

in cells P, Q and R.

Diagram 2
 Water can move from cell to cell.

Into which cell, P, Q or R, will water move the fastest?

(1)
(Total 4 marks)

Q6.
Villi are found in some parts of the digestive system.

Diagram 1 shows two villi.

Diagram 1

(a) Draw a ring around the correct answer to complete each sentence.

muscle.

(i) Structure A is a nerve.

capillary.
(1)
dialysis.

(ii) The villi absorb the products of digestion by diffusion.

 osmosis.
(1)

(b) Diagram 2 shows the digestive system.

Diagram 2

(i) In which part of the digestive system, X, Y or Z, are most villi found?
(1)

(ii) There are about 2000 villi in each cm2 of this part of the digestive system.

Why is it helpful to have lots of villi?

______________________________________________________________

______________________________________________________________
(1)
(Total 4 marks)

Q7.
The drawing shows a white blood cell ingesting a bacterium.
 (i) Use words from the list to label the parts of the white blood cell.

cell membrane cell wall cytoplasm nucleus vacuole

(3)

(ii) The scale shows that the white blood cell is 10 micrometres long.

How long is the bacterium? Show your working.

__________ micrometres
(2)
(Total 5 marks)

Q8.
The photograph shows part of the surface of a plant root. This part of the root is covered
with hundreds of structures like the one labelled X.
(a) What is the name of structure X?

Draw a ring around one answer.

root hair stoma villus

(1)

(b) (i) Use the scale to measure the length Y–Z on the photograph.

On the photograph, length Y–Z = __________________ mm.

(1)

(ii) The photograph shows the root magnified 100 times.

Calculate the actual length Y–Z.

______________________________________________________________

______________________________________________________________

______________________________________________________________

Actual length Y–Z = ___________________ mm.

(2)

(iii) Structure X is very small. There are thousands of structures like X on a plant
root.

How does this help the plant?

______________________________________________________________

______________________________________________________________

______________________________________________________________

______________________________________________________________
 (2)
(Total 6 marks)

Q9.
Diagram 1 shows an animal cell and some of the structures inside the cell.

(a) Use words from the box to label structures A, B and C, on Diagram 1.

Characteristic Chromosome Gamete Gene Nucleus

(3)

(b) Factors that may affect characteristics include genes and the environment.

Diagram 2 shows some of the characteristics of a girl.

Draw one line from each characteristic in List A to the factor(s) that affect the
characteristic in List B.

List A List B
Characteristic Factor(s) that affect the characteristic

Affected by genes only

 Blue eyes

Affected by environment only

Height 162 cm

Affected by both genes and the environment

Scar on arm

Affected by neither genes nor the environment

(3)
(Total 6 marks)

Q10.
Cells called receptors detect stimuli in the environment.

The diagram shows a light receptor cell.

Use words from the box to label structures A, B and C.

Cell membrane Cytoplasm Nucleus Synapse

(Total 3 marks)

Q11.
Complete the table by writing the correct process next to its description.

Choose your answers from the list in the box

breathing diffusion digestion osmosis respiration

Description Process

Moving air in and out of the lungs

 The movement of particles of a
substance
from high to low concentration

The release of energy from glucose

(Total 3 marks)

Q12.
The diagram shows an animal cell.

(a) (i) Name structures A and B by choosing the correct words from the box.

cell membrane cell wall cytoplasm nucleus vacuole

Structure A ___________________________________________________

Structure B ___________________________________________________
(2)

(ii) Which structure named in the box controls the passage of substances in and
out of the cell?

______________________________________________________________
(1)

(b) Distance P to Q on the diagram is the diameter of the cell. This distance was
measured on three cells using a microscope. The results were as follows:

cell 1: 63 micrometres
cell 2: 78 micrometres
cell 3: 69 micrometres

Calculate the average diameter of these cells. Show clearly how you work out your
final answer.
 ___________________________________________________________________

___________________________________________________________________

Average diameter = ___________________ micrometres

(2)
(Total 5 marks)

Q13.
(a) Put a tick ( ) in the correct boxes in the table below to show which of the parts
given are present in the cells and organisms listed.

CYTOPLASM NUCLEUS CELL WALL GENES

Leaf mesophyll cell

Sperm
(2)

(b) (i) What is the main job of a leaf mesophyll cell?

______________________________________________________________

______________________________________________________________
(1)

(ii) Explain one way in which the structure of the leaf mesophyll cell helps it to
carry out its job.

______________________________________________________________

______________________________________________________________

______________________________________________________________

______________________________________________________________
(2)
(Total 5 marks)

Q14.
The diagram shows an alveolus and a blood capillary in the lung.
 (i) During gaseous exchange, oxygen and carbon dioxide are exchanged across the
wall of the alveolus. On the diagram, carefully draw two arrows to show the paths
taken by oxygen and by carbon dioxide during this process. Label each arrow.
(3)

(ii) Name the process by which oxygen moves across the wall of the alveolus.

___________________________________________________________________

___________________________________________________________________
(1)

(iii) Each lung contains about 350 million alveoli. How does this help gaseous
exchange?

___________________________________________________________________

___________________________________________________________________
(1)
(Total 5 marks)

Q15.
The diagram shows a cell from a plant leaf.
 (a) Name the part of this cell that:

(i) controls the passage of substances in and out of the cell

______________________________________________________________
(1)

(ii) is filled with cell sap.

______________________________________________________________
(1)

(b) Give the names of two parts of the leaf cell that would not be found in a human
liver cell.

_________________________ and _________________________

(2)

(c) The chloroplasts produce oxygen.

Draw a ring around the correct answer to complete the sentence.

diffusion.

The oxygen produced by the chloroplasts passes out of the cell by digestion.

respiration.
(1)
(Total 5 marks)

Q16.
The diagram shows a group of muscle cells from the wall of the intestine.
 (a) On the diagram, use words from the box to name the structures labelled A, B and
C.

cell membrane cell

wall chloroplast cytoplasm nucleus

(3)

(b) How are these muscle cells adapted to release a lot of energy?

___________________________________________________________________

___________________________________________________________________

___________________________________________________________________
(2)
(Total 5 marks)

Q17.
The diagram shows a small part of a lung.
(a) The arrow on the diagram shows the movement of oxygen from the air in the
alveolus to cell X.

Complete the sentences by drawing a ring around the correct answer.

platelet

(i) Cell X is a red cell

white cell
(1)

diffusion

(ii) Oxygen moves from the air in the alveolus into cell X by filtration

respiration
(1)

glycogen

(iii) The substance in cell X that combines with oxygen is called haemoglobin

lactic acid
(1)
 a cell
membrane

(iv) Cell X does not have

cytoplasm

a nucleus
(1)

(b) On the diagram, draw an arrow to show the movement of carbon dioxide during
gas exchange.
(1)
(Total 5 marks)

Q18.
The diagram shows a cell from the lining of the lung. This cell is specialised to allow gases
to pass through quickly.

(a) Use words from the box to label structures A, B and C.

cell
chloroplast cytoplasm mitochondria nucleus
membrane
(3)

(b) (i) Which feature of this cell allows oxygen to pass through quickly?

Put a tick ( ) in the box next to your choice.

It is thin.

It has a large nucleus.

It has many
mitochondria.

(1)

(ii) Complete the sentence by drawing a ring around the correct answer in the
box.
 diffusion
Oxygen passes through this cell
osmosis
by
respiration
(1)
(Total 5 marks)

Q19.
(a) The diagrams show cells containing and surrounded by oxygen molecules.
Oxygen can move into cells or out of cells.

Into which cell, A, B, C or D, will oxygen move the fastest?

Write your answer, A, B, C or D, in the box.

(1)

(b) Draw a ring around the correct word to complete each sentence.

diffusion

(i) Oxygen is taken into cells by the process of osmosis .

respiration
(1)
 breathing

(ii) Cells need oxygen for photosynthesis .

respiration
(1)

membranes

(iii) The parts of cells that use up the most oxygen are the mitochondria .

nuclei
(1)

diffusion

(iv) Some cells produce oxygen in the process of photosynthesis .

respiration
(1)
(Total 5 marks)

Q20.
Diagram 1 shows the nucleus of a body cell as it begins to divide by mitosis.

Diagram 1

(a) Use a word from the box to label Diagram 1.

alleles chromosomes gametes

(1)

(b) Complete Diagram 2 to show what the nucleus of one of the cells produced by this
mitosis would look like.

Diagram 2
 (1)

(c) Stem cells from a recently dead embryo can be grown in special solutions.

Some facts about stem cells are given below.

• Stem cells from an embryo can grow into any type of tissue.

• Stem cells may grow out of control, to form cancers.

• Large numbers of stem cells can be grown in the laboratory.

• Stem cells may be used in medical research or to treat some human diseases.

• Patients treated with stem cells need to take drugs for the rest of their life to
prevent rejection.

• Collecting and growing stem cells is expensive.

Use only the information above to answer these questions.

(i) Give two advantages of using stem cells.

1. ____________________________________________________________

______________________________________________________________

2. ____________________________________________________________

______________________________________________________________
(2)

(ii) Give two disadvantages of using stem cells.

1. ____________________________________________________________

______________________________________________________________

2. ____________________________________________________________

______________________________________________________________
(2)
(Total 6 marks)

Q21.
A woman gives birth to triplets.
Two of the triplets are boys and the third is a girl.
The triplets developed from two egg cells released from the ovary at the same time.
The diagram shows how triplets A, B and C developed.

(a) Which stages on the diagram show gametes?

Draw a ring around your answer.

1 and 2 2 and 3 3 and 7 1 and 7

(1)

(b) Embryo B is male.

Which of the following explains why embryo B is male?

Tick ( ) one box.

Cell P has an X chromosome; cell R has an X chromosome.

Cell P has a Y chromosome; cell R has an X chromosome.

Cell P has an X chromosome; cell R has a Y chromosome.

(1)

(c) The children that develop from embryos A and C will not be identical.

Explain why.

You may use words from the box in your answer.

egg genes sperm

 ___________________________________________________________________

___________________________________________________________________

___________________________________________________________________

___________________________________________________________________

___________________________________________________________________
(2)

(d) Single cells from an embryo at Stage 7 can be separated and grown in a special
solution.

(i) What term describes cells that are grown in this way?

Draw a ring around your answer.

lleles screened cells stem cells

(1)

(ii) What happens when the cells are placed in the special solution?

Tick ( ) two boxes.

The cells divide

The cells fertilise

The cells differentiate

The cells separate

(2)

(iii) Give one use of cells grown in this way.

______________________________________________________________

______________________________________________________________
(1)

(iv) Some people might object to using cells from embryos in this way.

Give one reason why.

______________________________________________________________

______________________________________________________________

______________________________________________________________
(1)
(Total 9 marks)
Q22.

Diagram 1 shows a cell from a leaf.

Diagram 1

(a) How is the leaf cell specialised to carry out photosynthesis?

Tick ( ) one box.

It has a permanent vacuole.

It has many chloroplasts.

It has cytoplasm.

It has many mitochondria.

(1)

(b) Diagram 2 shows another type of plant cell.

Diagram 2

Give two ways in which this cell is different from an animal cell.

1. _________________________________________________________________

___________________________________________________________________

2. _________________________________________________________________

___________________________________________________________________
 (2)
(Total 3 marks)

Q23.
This question is about cells.

(a) (i) The diagram shows a sperm cell.

Use words from the box to label parts A and B.

cell membrane cytoplasm nucleus

(2)

(ii) The diagram shows a cell from a leaf.

Give the letters of two parts of the leaf cell which would not be found in a

sperm cell. and .

(1)

(b) Sperm cells have many mitochondria.

Why do sperm cells need many mitochondria?

Tick ( ) one box.

Sperm cells are involved in fertilisation.

Sperm cells are produced in very large numbers.

Sperm cells need a lot of energy to swim.

(1)
(Total 4 marks)
Q24.
The diagram shows part of a plant root. A large number of structures like the ones labelled
X grow out of the surface of the root.

(a) (i) What is the name of structure X?

Draw a ring around one answer.

root hair stoma villus

(1)

(ii) Name two substances which structure X absorbs from the soil.

1. ____________________________________________________________

2. ____________________________________________________________
(2)

(b) The substances in (a)(ii) are transported from the roots to the leaves. Carbon
dioxide also enters the leaves.

Draw a ring round the correct answer to complete each sentence.

alveoli.

(i) Carbon dioxide enters leaves through stomata.

villi.
(1)

active transport.

(ii) Carbon dioxide enters leaf cells by diffusion.

reabsorption.
(1)
(Total 5 marks)
Q25.
(a) List A gives four structures in the human body.

List B gives the functions of some structures in the body.

Draw a straight line from each structure in List A to the correct function in List B.

List A – Structure List B – Function

Surround and protect the lungs

Alveoli

Filter the blood

Veins

Carry blood towards the heart

Villi

Absorb digested food

Ribs

Allow oxygen to enter the blood

(4)

(b) Draw a ring around the correct answer to complete the sentence.

diffusion.

In the lungs, oxygen enters the blood from the air by filtration.

respiration.
(1)
(Total 5 marks)

Q26.
The diagrams show four types of cell, A, B, C and D.
Two of the cells are plant cells and two are animal cells.
(a) (i) Which two of the cells are plant cells?

Tick ( ) one box.

A and B

A and D

C and D

(1)

(ii) Which part is found only in plant cells?

Draw a ring around one answer.

cell membrane cell wall nucleus

(1)

(b) (i) Which cell, A, B, C or D, is adapted for swimming?

(1)
 (ii) Which cell, A, B, C or D, can produce glucose by photosynthesis?

(1)

(c) Cells A, B, C and D all use oxygen.

For what process do cells use oxygen?

Draw a ring around one answer.

osmosis photosynthesis respiration

(1)
(Total 5 marks)

Q27.
The diagram shows part of the lining of the small intestine.

(a) (i) Name structure X.

Draw a ring around one answer.

alveolus thorax villus

(1)

(ii) Choose three ways in which structure X is adapted to help the absorption of
soluble food.

Tick ( ) three boxes.

It is ventilated.

Its outer surface is one cell thick.

 It has a large surface area.

It contains a layer of muscle.

It has a good blood supply.

Its cells contain haemoglobin.

(3)

(b) Name the process by which soluble food enters the blood.

Draw a ring around one answer.

diffusion fermentation transpiration

(1)
(Total 5 marks)

Q28.
Humans reproduce sexually.

Draw a ring around the correct answer to complete each sentence.

chromosomes
(a) (i) At fertilisation genes join together.
sex cells
(1)

chromosomes.
(ii) At fertilisation a single cell forms, which has new pairs of nuclei.
sex cells.
(1)

(b) Cystic fibrosis can be inherited by children whose parents do not have it.

two
(i) A person who has cystic fibrosis has three copies of the
four

cystic fibrosis allele.

(1)

large.
(ii) The cystic fibrosis allele is recessive.
 strong.
(1)

(c) The diagram shows a human body cell.

Choose the correct answer from the box to complete each sentence.

cell cell wall cytoplasm nucleus

membrane

(i) The part of the cell labelled B is the _______________________________

(1)

(ii) The part of the cell labelled C is the _______________________________

(1)

(d) Which part of the cell, A, B, C or D:

(i) contains the allele for cystic fibrosis

(1)

(ii) is affected by cystic fibrosis?

(1)
(Total 8 marks)

Q29.
Leaves are made from layers of cells.

The diagram shows a section through part of a leaf.

(a) (i) Which word in the table describes layer A?

Tick ( ) one box.

Layer A Tick
( )

Tissue

Organ

Cell
(1)

(ii) Which word describes a whole leaf?

Draw a ring around one answer.

organ tissue organism

(1)

(b) (i) Which two layers of cells, A, B, C and D, can photosynthesise?

Use information from the diagram to help you.

Tick ( ) two boxes.

Layer A
 Layer B

Layer C

Layer D

(2)

(ii) Give one reason for your answer.

______________________________________________________________

______________________________________________________________
(1)

(c) List X gives the names of two parts of a cell.

List Y gives information about parts of a cell.

Draw one line between each part of the cell in list X and information about it in list Y.

List X List Y
Part of a cell Information

Controls the passage of

substances into the cell

Vacuole

Contains the cell sap

Nucleus

Controls the activities of the

whole cell
(2)
(Total 7 marks)

Q30.
The diagram shows a plant cell from a leaf.
(a) List A gives the names of three parts of the cell.
List B gives the functions of parts of the cell.

Draw a line from each part of the cell in List A to its function in List B.

List A List B
Parts of the cell Functions

Where most of the chemical

reactions take place

Nucleus

Absorbs light energy to make food

Cytoplasm

Strengthens the cell

Chloroplast

Controls the activities of the cell

(3)

(b) Respiration takes place in the cell.

Draw a ring around the correct answer to complete the sentence.

energy

All cells use respiration to release oxygen.

sugar.
(1)
 (Total 4 marks)

Q31.
Villi are found in some parts of the digestive system.

Diagram 1 shows two villi.

(a) Draw a ring around the correct answer to complete each sentence.

muscle.

(i) Structure A is a nerve.

capillary.
(1)

dialysis.

(ii) The villi absorb the products of digestion by diffusion.

osmosis.
(1)

(b) Diagram 2 shows the digestive system.

 (i) In which part of the digestive system, X, Y or Z, are most villi

found?
(1)

(ii) There are about 2000 villi in each cm2 of this part of the digestive system.

Why is it helpful to have lots of villi?

______________________________________________________________

______________________________________________________________
(1)
(Total 4 marks)

Q32.
Substances can move into and out of cells.

(a) (i) How does oxygen move into and out of cells?

Draw a ring around one answer.

diffusion digestion photosynthesis

(1)

(ii) Diagram 1 shows the percentage concentration of oxygen in three cells, A, B

and C.
 Oxygen can move from cell to cell.

Into which cell, A, B or C, will oxygen move the fastest?

(1)

(b) (i) How does water move into and out of cells?

Draw a ring around one answer.

breathing osmosis respiration

(1)

(ii) Differences in the concentration of sugars in cells cause water to move into or
out of cells at different rates.

Diagram 2 shows three different cells, P, Q and R.

The information shows the percentage concentration of sugar solution in cells

P, Q and R.

Water can move from cell to cell.

 Into which cell, P, Q or R, will water move the fastest?
(1)
(Total 4 marks)

Q33.
The diagram shows a strawberry plant.

The parent plant grows side shoots.

New plants grow on the side shoots.

© D.G. Mackean

The new plants will all have the same inherited characteristics as the original parent plant.

Complete the sentences to explain why.

Use words from the box.

asexual differentiation embryos fertilisation

gametes genes mitosis sexual

(a) The new plant is produced by ___________________________________

reproduction.
(1)

(b) In this type of reproduction, body cells divide by ____________________________

(1)

(c) The new plant has the same ______________________________ as the parent
plant.
(1)
(Total 3 marks)

Q34.
(a) The diagram shows the structure of a bacterial cell.
 (i) On the diagram use words from the box to label structures A, B and C.

cell membrane cell wall chloroplast cytoplasm plasmid

(3)

(ii) Give one difference between the structure of the bacterial cell and an animal
cell.

______________________________________________________________
(1)

(iii) Name one structure that is found in a plant cell but is not found in a bacterial
or an animal cell.

______________________________________________________________
(1)

(b) Cells can be specialised for a particular job.

The diagram shows the structure of a human sperm cell.

Describe how the long tail and the mitochondria help the sperm to do its job.

Long tail ___________________________________________________________

___________________________________________________________________

___________________________________________________________________

Mitochondria ________________________________________________________

___________________________________________________________________

___________________________________________________________________
(4)
(Total 9 marks)

Q35.
The diagrams show four types of cell, A, B, C and D.
Two of the cells are plant cells and two are animal cells.
(a) (i) Which two of the cells are plant cells?

Tick ( ) one box.

A and B

A and D

C and D

(1)

(ii) Give one reason for your answer.

______________________________________________________________

______________________________________________________________
(1)

(b) (i) Which cell, A, B, C or D, is adapted for swimming?

(1)

(ii) Which cell, A, B, C or D, can produce glucose by photosynthesis?

(1)
 (c) Cells A, B, C and D all use oxygen.

For what process do cells use oxygen?

Draw a ring around one answer.

osmosis photosynthesis respiration

(1)
(Total 5 marks)

Q36.
The diagram shows an alveolus and a blood vessel in the lung.

(a) Draw a ring around the correct answer to complete each sentence.

an artery.

(i) Blood vessel X is a capillary.

a vein.
(1)

diffusion.

(ii) Gases pass across the wall of the alveolus by evaporation.

fermentation.
(1)

(iii) The table compares the concentrations of some gases in inhaled air and
 exhaled air.

Complete the table.

Write ‘lower’ or ‘higher’ in each box.
One line has been completed for you as an example.

Concentration
Gas
Inhaled air Exhaled air

Water vapour lower higher

Carbon dioxide

Oxygen
(2)

(b) Draw a ring around the correct answer to complete each sentence.

blood plasma.

(i) Oxygen is carried in the blood mainly in red blood cells.

white blood cells.

(1)

carbon dioxide.

(ii) In the blood, the oxygen combines with haemoglobin.

urea.
(1)
(Total 6 marks)

Q37.
Stem cells can be collected from human embryos and from adult bone marrow.
Stem cells can develop into different types of cell.

The table gives information about using these two types of stem cell to treat patients.

Stem cells from human embryos Stem cells from adult bone marrow

It costs £5000 to collect a few cells. It costs £1000 to collect many cells.

There are ethical issues in using Adults give permission for their own
embryo stem cells. bone marrow to be collected.

The stem cells can develop into most The stem cells can develop into only a
other types of cell. few types of cell.

Each stem cell divides every 30 Each stem cell divides every four
 minutes. hours.

There is a low chance of a patient’s There is a high chance of a patient’s

immune system rejecting the cells. immune system rejecting the cells.

More research is needed into the use Use of these stem cells is considered
of these stem cells. to be a safe procedure.

Scientists are planning a new way of treating a disease, using stem cells.

Use only the information above to answer these questions.

(a) Give three advantages of using stem cells from embryos instead of from adult bone
marrow.

1. _________________________________________________________________

2. _________________________________________________________________

3. _________________________________________________________________
(3)

(b) Give three advantages of using stem cells from adult bone marrow instead of from
embryos.

1. _________________________________________________________________

2. _________________________________________________________________

3. _________________________________________________________________
(3)
(Total 6 marks)

Q38.
The diagrams show four cells, A, B, C and D.

A B

C D

Use letters A, B, C or D to answer these questions.

(a) Which cell can photosynthesise?

 (1)

(b) Which cell is adapted for receiving and sending information?

(1)

(c) Which cell is adapted to respire quickly?

(1)
(Total 3 marks)

Q39.
People have different shaped ear lobes, either ‘hanging’ or ‘attached’.

The diagrams show the two shapes of ear lobe.

A gene controls the shape of a person’s ear lobes.

The diagram shows a family tree.

Parents A and B both have hanging ear lobes.

(a) The key does not show the symbol for a female with attached ear lobes.

Draw the symbol for the key to show a female with attached ear lobes.

Use information in the family tree and the key.

Symbol = ______________________________
(1)

(b) Look at the family tree.

 What does the information in the family tree tell you about the allele for hanging ear
lobes?

Draw a ring around the correct word to complete the sentence.

dominant.

The allele for hanging ear lobes is weak.

recessive.
(1)

(c) (i) Parents A and B have three children, C, D and E.

All three children are boys.

What are the chances that the next child of parents A and B will be a girl?

Draw a ring around one answer.

no chance (0 %) a half (50 %) certain (100 %)

(1)

(ii) Which statement explains your answer to part (c)(i)?

Tick ( ) one box.

Some of B’s sperm cells have an X chromosome.

Some of A’s egg cells have a Y chromosome

All of B’s sperm cells have an X chromosome.

(1)
(Total 4 marks)

Q40.
The diagram shows a section through a plant leaf.
 (a) Use words from the box to name two tissues in the leaf that transport substances
around the plant.

epidermis mesophyll phloem xylem

______________________________ and ______________________________

(1)

(b) Gases diffuse between the leaf and the surrounding air.

(i) What is diffusion?

______________________________________________________________

______________________________________________________________

______________________________________________________________

______________________________________________________________
(2)

(ii) Name one gas that will diffuse from point A to point B on the diagram on a
sunny day.

______________________________________________________________
(1)
(Total 4 marks)

Q41.
In sexual reproduction, an egg fuses with a sperm.

(a) (i) Draw a ring around the correct answer to complete the sentence.
 cloning.

An egg and a sperm fuse together in the process of fertilisation.

mitosis.
(1)

(ii) Egg cells and sperm cells each contain the structures given in the box.

chromosome gene nucleus

List these three structures in size order, starting with the smallest.

1 ____________________________________________________ (smallest)

2. ____________________________________________________________

3 _____________________________________________________ (largest)
(2)

(iii) The egg and the sperm contain genetic material.

Draw a ring around the correct answer to complete the sentence.

carbohydrate.

The genetic material is made of DNA.

protein.
(1)

(b) The diagram below shows the inheritance of X and Y chromosomes.

(i) Draw a tick ( ) on the part of the diagram that shows a sperm cell.
(1)

(ii) What is the chance of having a female child?

Give the reason for your answer.

______________________________________________________________
 ______________________________________________________________

______________________________________________________________

______________________________________________________________
(2)
(Total 7 marks)

Q42.
The diagrams show an animal cell and a bacterial cell.

(a) (i) Structures A and B are found in both the animal cell and the bacterial cell.

Use words from the box to name structures A and B.

cell membrane chloroplast cytoplasm vacuole

A ______________________________

B ______________________________
(2)

(ii) Both cells contain genetic material.

Name the structure in the animal cell that contains genetic material.

______________________________________________________________
(1)

(b) List A gives three structures found in animal cells.

List B gives four functions of cell structures.

Draw one line from each structure in List A to its correct function in List B.

List A –
List B – Function
Structure

Controls what substances

enter the cell
 Cell membrane

Photosynthesis

Mitochondrion

Protein synthesis

Ribosome

Respiration

(3)
(Total 6 marks)

Q43.
(a) (i) Mitosis and meiosis are types of cell division.

For each feature in the table, tick ( ) one box to show if the feature occurs:

• only in mitosis

• only in meiosis.

Only in Only in
Feature mitosis mitosis
( ) ( )

Produces new cells during growth and repair

Produces gametes (sex cells)

Produces genetically identical cells

(2)

(ii) Name the organ that produces gametes (sex cells) in:

a man ______________________

a woman ____________________
(2)

(b) X and Y chromosomes are the sex chromosomes. They determine a person’s sex.

What sex chromosomes will be found in the body cells of:

(i) a man ______________________

(1)
 (ii) a woman? ____________________
(1)

(c) A man and a woman decide to have a child.

What is the chance that the child will be a boy? ________________________

(1)
(Total 7 marks)

Q44.
The diagram shows a cell.

(a) (i) Use words from the box to name the structures labelled A and B .

cell membrane chloroplast cytoplasm nucleus

A ___________________________

B ___________________________
(2)

(ii) The cell in the diagram is an animal cell.

How can you tell it is an animal cell and not a plant cell?

Give two reasons.

1. ____________________________________________________________

______________________________________________________________

2. ____________________________________________________________

______________________________________________________________
(2)

(b) Oxygen will diffuse into the cell in the diagram.

 Why?

Use information from the diagram.

___________________________________________________________________

___________________________________________________________________
(1)

(c) The cell shown in the diagram is usually found with similar cells.

Draw a ring around the correct answer to complete the sentence.

an organ.

Scientists call a group of similar cells a system.

a tissue.
(1)
(Total 6 marks)

Q45.
When an organism grows, new cells are produced by cell division.

(a) What type of cell division happens to produce new body cells?

Tick one box.

Differentiation

Meiosis

Mitosis

(1)

(b) Why can cancers grow very large?

Tick one box.

Cancer cells are specialised

Cell division is slow

Cell division is uncontrolled

(1)

(c) Give one factor which increases the risk of getting cancer.
 ___________________________________________________________________
(1)

(d) Survival rates for people with cancer have improved a lot.

People who are alive 10 years after diagnosis are usually considered to be cured.

The figure below shows data for people diagnosed with cancer in 1961 and 2001.

78% of people diagnosed with breast cancer in 2001 were alive 10 years later.

Complete the figure above to show this information.

(1)

(e) Which type of cancer diagnosed in 1961 had the highest survival rate?

Tick one box.

Breast

Prostate

Skin

Testicular

(1)

(f) Which type of cancer shows the biggest improvement in the percentage of people
 alive after 10 years?

Tick one box.

Breast

Prostate

Skin

Testicular

(1)

(g) Suggest two reasons why the survival rates for all cancers have increased.

1. _________________________________________________________________

___________________________________________________________________

2. _________________________________________________________________

___________________________________________________________________
(2)
(Total 8 marks)

Q46.
Human cells and yeast cells have some parts that are the same.

(a) The diagram shows a yeast cell.

Parts A and B are found in human cells and in yeast cells. On the diagram, label
parts A and B.
(2)

(b) Many types of cell can divide to form new cells.

Some cells in human skin can divide to make new skin cells.

Why do human skin cells need to divide?

 ___________________________________________________________________

___________________________________________________________________
(1)

(c) Human stem cells can develop into many different types of human cell.

(i) Use the correct answer from the box to complete the sentence.

embryos hair nerve cells

Human stem cells may come from

______________________________________________________________
(1)

(ii) Use the correct answer from the box to complete the sentence.

cystic fibrosis paralysis polydactyly

Human stem cells can be used to treat

______________________________________________________________
(1)
(Total 5 marks)

Q47.
(a) Some antibiotics work by destroying the cell membranes of bacteria.

Suggest why these antibiotics may have side effects in the animals that are given
these antibiotics.

___________________________________________________________________
(1)

(b) Each arrow on the figure below shows the date of discovery of each new type of
antibiotic.

In which 10 year period were most new types of antibiotic discovered?

___________________________________________________________________
(1)

(c) The figure above shows 22 new types of antibiotic. These were discovered before
2010.

Determine the percentage of types of antibiotic that have been discovered between
1980 and 2010.

Use information from the figure above.

Give your answer to 2 significant figures.

 ___________________________________________________________________

___________________________________________________________________

____________________ %
(2)

(d) Bacteria can evolve rapidly.

Many bacteria can develop into new strains which are resistant to antibiotics.

Complete the table below to show if each action is more likely or less likely to help
bacteria to become antibiotic resistant.

Put a tick in each row.

More Less
Action
likely likely

Take painkillers for headache

Washing with antiseptic hand gel

Adding antibiotics to food for cows

Giving antibiotics for colds and flu

Stopping antibiotics as soon as you

feel better
(4)
(Total 8 marks)

Q48.
The image below shows some cells in the lining of the stomach.

(a) (i) Use words from the box to name structures A and B.

cell membrane chloroplast cytoplasm vacuole

A _____________________________________

B _____________________________________
(2)

(ii) What is the function of the nucleus?

Tick ( ) one box.

 To control the activities of the cell

To control movement of substances into and out of the cell

To release energy in respiration

(1)

(b) Draw one line from each part of the human body to its correct scientific name.

Part of human body Scientific name

An organ

Layer of cells lining the

stomach

An organism

Stomach

An organ system

Mouth, stomach, intestines,

liver and pancreas

A tissue
(3)
(Total 6 marks)

Q49.
The diagram below shows the parts of the body that digest and absorb food.

It also shows some details about the structure of the stomach.

(a) Complete the table to show whether each structure is an organ, an organ system or
a tissue.

For each structure, tick ( ) one box.

Organ
Structure Organ Tissue
system

Stomach

Cells lining the stomach

Mouth, oesophagus, stomach, liver,

pancreas, small and large intestine
(2)

(b) (i) The blood going to the stomach has a high concentration of oxygen.
The cells lining the stomach have a low concentration of oxygen.

Complete the following sentence.

Oxygen moves from the blood to the cells lining the stomach by

the process of ___________________________________ .

(1)

(ii) What other substance must move from the blood to the cells lining the
stomach so that respiration can take place?

Draw a ring around the correct answer.

glucose protein starch

(1)
 (iii) In which part of a cell does aerobic respiration take place?

Draw a ring around the correct answer.

cell membrane mitochondria nucleus

(1)
(Total 5 marks)

Q50.
Plants need different substances to survive.

Figure 1 shows the roots of a plant.

(a) (i) Mineral ions are absorbed through the roots.

Name one other substance absorbed through the roots.

______________________________________________________________
(1)

(ii) The plant in Figure 1 has a higher concentration of mineral ions in the cells of
its roots than the concentration of mineral ions in the soil.

Which two statements correctly describe the absorption of mineral ions into
the plant’s roots?

Tick ( ) two boxes.

The mineral ions are absorbed by active transport.

The mineral ions are absorbed by diffusion.

The mineral ions are absorbed down the concentration

gradient.
 The absorption of mineral ions needs energy.

(2)

(iii) The plant in Figure 1 has roots adapted for absorption.

Figure 2 shows a magnified part of a root from Figure 1.

Describe how the root in Figure 2 is adapted for absorption.

______________________________________________________________

______________________________________________________________

______________________________________________________________

______________________________________________________________
(2)

(b) The leaves of plants have stomata.

What is the function of the stomata?

___________________________________________________________________

___________________________________________________________________
(1)

(c) Figure 3 shows the underside of two leaves, A and B, taken from a plant in a man’s
house.
 (i) In Figure 3, the cells labelled X control the size of the stomata.

What is the name of the cells labelled X?

Tick ( ) one box.

Guard cells

Phloem cells

Xylem cells

(1)

(ii) Describe how the appearance of the stomata in leaf B is different from the
appearance of the stomata in leaf A.

______________________________________________________________

______________________________________________________________
(1)

(iii) The man forgets to water the plant.

What might happen to the plant in the next few days if the stomata stay the
same as shown in leaf A in Figure 3?

______________________________________________________________

______________________________________________________________
(1)
(Total 9 marks)

Q51.
Our lungs help us to breathe.
The image below shows the human breathing system.

(a) (i) Name part A.

______________________________________________________________
(1)

(ii) Give one function of the ribs.

______________________________________________________________
(1)

(b) (i) Use the correct answer from the box to complete the sentence.

active transport diffusion osmosis

Oxygen moves from the air inside the lungs into the blood by the

process of __________________________ .
(1)

(ii) Use the correct answer from the box to complete the sentence.

arteries capillaries veins

Oxygen moves from the lungs into the blood through the walls

of the __________________________ .
(1)

(iii) Inside the lungs, oxygen is absorbed from the air into the blood.

Give two adaptations of the lungs that help the rapid absorption of oxygen into
the blood.

1. ____________________________________________________________

______________________________________________________________
 2. ____________________________________________________________

______________________________________________________________
(2)
(Total 6 marks)

Q52.
Pathogens cause infectious diseases in animals and plants.

(a) Draw one line from each disease to the type of pathogen that causes the disease.

Disease Type of pathogen

Bacterium

Gonorrhoea

Fungus

Malaria

Protist

Measles

Virus
(3)

(b) Some parts of the human body have adaptations to reduce the entry of live
pathogens.

Look at Figure 1.

Figure 1

Explain how the trachea is adapted to reduce the entry of live pathogens.

___________________________________________________________________

___________________________________________________________________

___________________________________________________________________

___________________________________________________________________

___________________________________________________________________

___________________________________________________________________
 ___________________________________________________________________

___________________________________________________________________

___________________________________________________________________
(4)

(c) Malaria is a serious disease that can be fatal.

Malaria is spread to humans by infected mosquitoes.

Scientists investigated the behaviour of mosquitoes to understand how the spread of

malaria could be controlled.

Figure 2 shows the equipment the scientists used.

Figure 2

This is the method used.

1. 30 mosquitoes infected with malaria were placed in Container A.

2. 30 uninfected mosquitoes were placed in Container B.

3. The total number of times the mosquitoes landed on the socks was recorded.

Name the dependent variable and suggest one control variable in this investigation.

Dependent variable ___________________________________________________

___________________________________________________________________

Control variable ______________________________________________________

___________________________________________________________________
(2)

(d) Infected mosquitoes landed on the socks three times more often than uninfected
mosquitoes.

Explain how this information can be used to reduce the spread of malaria.

___________________________________________________________________

___________________________________________________________________

___________________________________________________________________
 ___________________________________________________________________
(2)

(e) Tobacco mosaic virus (TMV) affects many species of plant.

Figure 3 shows a leaf infected with TMV.

Figure 3

© Nigel Cattlin/Getty Images

TMV destroys chloroplasts in the leaf.

Explain how this could affect the growth of the plant.

___________________________________________________________________

___________________________________________________________________

___________________________________________________________________

___________________________________________________________________

___________________________________________________________________

___________________________________________________________________
(3)
(Total 14 marks)
Mark schemes

Q1.
(a) cell membrane
extra boxes ticked negates mark
1

(b) nucleus
extra boxes ticked negates mark
1

(c) has a tail so it can swim (to an egg)

accept has many mitochondria to release energy to swim
1

(d)

all three correct for 2 marks

one or two correct for 1 mark
2
[5]

Q2.
(a) 8 (micrometres)
1

(b) red blood cell(s)

1

white blood cell(s)

accept named cell
eg phagocyte / lymphocyte
 1

(plasma)
transports proteins / dissolved substances / food (molecules) / urea / hormones /
blood
cells
1

(c) any one from:

• you could lose a lot of blood

• bleed internally
allow bleeding would not stop
allow could bleed to death
1
[5]

Q3.
(a) osmosis
1

partially permeable
1

(b) (i) any two from:

allow correct answers in terms of A

• vacuole is small(er)
• cytoplasm has shrunk
allow cytoplasm is smaller
• gap between cytoplasm and cell wall
• cell wall curves inwards
allow cell B is flaccid or cell A is turgid
• the (cell) membrane has moved away from the wall
2

(ii) any one from:

• water will move / diffuse in

• (cells) will swell
• (cells) will burst
ignore turgid
1

(c) villi give the small intestines a large surface area

1

villi have many blood capillaries

1
[7]

Q4.
(a) A sperm
1

B egg
1
 C fertilised egg
1

D embryo
1

(b) insert into mother

ignore fertilise / check fertilisation / check viability
1

womb / uterus
1

(c) (i) one quarter

1

(ii) no / little chance of success over 42

1

reference to table of only two women in the age bracket 40-42 years
became pregnant
the statement „only 2 out of 53 40-42 year old women
became pregnant / had babies‟ gains 2 marks
1

(iii) so fewer twins / multiple births

or
multiple births more dangerous
1
[10]

Q5.
(a) (i) diffusion
apply list principle
1

(ii) A
apply list principle
1

(b) (i) osmosis

apply list principle
1

(ii) R
apply list principle
1
[4]

Q6.
(a) (i) capillary
1

(ii) diffusion
1

(b) (i) Z
ignore any names
 1

(ii) large / increased surface / area

allow all food absorbed

or to absorb more food

or improved diffusion
1
[4]

Q7.
(i) cytoplasm
(cell) membrane
nucleus
all correctly labelled
each for 1 mark
3

(ii) 0.5
gains 2 marks
(5/100 × 10 or ½ /1 gains 1 mark if 0.5 not given)
2
[5]

Q8.
(a) root hair
1

(b) (i) 85
if incorrect unit added = 0
1

(ii) 0.85
ignore working or lack of working
accept correct answer from candidate‟s (i) for 2 marks

with no answer or wrong answer gains 1 mark

accept ecf
2

(iii) absorb more water / ions

allow „get / collect / take in / take up / soak up / suck up‟ for
absorb
allow „lots‟ for more
allow „moisture‟ for water
allow „minerals / salts / nutrients‟ for ions
do not allow food or named foods
absorb water / ions gains 1 mark

or

large surface area to absorb water / ions (2)

large surface area linked to incorrect function = 1
ignore small so short diffusion pathway
 2
[6]

Q9.
(a) A – nucleus
1

B – chromosome
1

C – gene
1

(b)

extra line from statement cancels the mark

3
[6]

Q10.
A – (cell) membrane
1

B – cytoplasm
1

C – nucleus
1
must be in correct order
accept phonetic spelling – see marking guidance 3.6
[3]

Q11.
in correct sequence:

breathing
1

diffusion
1

respiration
1
[3]

Q12.
(a) (i) A = nucleus
 1

B = (cell) membrane
1

(ii) (cell) membrane

1

(b) 70
if correct answer, ignore working or lack of working

for 1 mark
2
[5]

Q13.
(a) mesophyll / / / / (all correct) sperm / / x / (all correct)
for 1 mark each
2

(b) (i) absorbs light/to produce food/photosynthesis

(allow references to gaseous exchange)
for 1 mark
1

(ii) has chlorophyll/chloroplasts to absorb light/produce food

for 1 mark each
(if linked to gas exchange allow – moist surface/
dissolve gases)
2
[5]

Q14.
(i) On diagram:

oxygen arrow to blood from air and CO2 arrow to air from blood
1

oxygen arrow to red blood cell

1

CO2 arrow from plasma

1

(ii) diffusion
1

(iii) large surface or large area

do not accept space
1
[5]

Q15.
(a) (i) (cell) membrane
1
 (ii) vacuole
1

(b) any two from:

• (cell) wall

• chloroplast(s)
ignore chlorophyll

• vacuole
ignore cell sap
2

(c) diffusion
1
[5]

Q16.
(a) A nucleus
1

B (cell) membrane
1

C cytoplasm
1

(b) any two from:

• (contain mitochondria

• many (mitochondria)

• respiration (occurs in mitochondria)

2
[5]

Q17.
(a) (i) red cell
1

(ii) diffusion
1

(iii) haemoglobin
1

(iv) a nucleus
1

(b) (on diagram) arrow from any part of blood to air

1
[5]

Q18.
(a) A nucleus
1
 B (cell) membrane
1

C cytoplasm
1

(b) (i) it is thin

1

(ii) diffusion
1
[5]

Q19.
(a) A
1

(b) (i) diffusion

1

(ii) respiration
1

(iii) mitochondria
1

(iv) photosynthesis
1
[5]

Q20.
(a) chromosomes
1

(b) diagram showing four separate chromosomes two long and two short
(as in diagram 1)
allow each chromosome shown as two joined chromatids
do not allow if chromosomes touching each other
1

(c) (i) any two from:

• can grow into any type of tissue / named tissue

• used in medical research

• used to treat human diseases

• large numbers can be grown

2

(ii) any two from:

• expensive

• grow out of control / ref cancers

• may be rejected

• need for drugs (for rest of life)

 2
[6]

Q21.
(a) 2 and 3
1

(b) cell P has an X chromosome; cell R has a Y chromosome

1

(c) any two from:

• (formed from) different egg / 2 eggs

• (formed from) different sperm / 2 sperm

• have different genes / alleles / chromosomes / DNA

allow genetics
2

(d) (i) stem cells

1

(ii) the cells divide

1

the cells differentiate

1

(iii) (medical) research / named eg growing organs

or

medical / patient treatment

allow (embryo) cloning
do not allow designer babies / more babies
1

(iv) any one from:

• ethical / moral / religious objections

ignore cruel / not natural / playing God

• potential harm to embryo

allow deformed
ignore harm to mother
1
[9]

Q22.
(a) it has many chloroplasts.
1

(b) (has) cell wall

1

(has) vacuole or large / permanent vacuole

do not allow chloroplasts
assume plant cell throughout
 accept converse for animal cell
1
[3]

Q23.
(a) (i) A cytoplasm
accept clear indications
1

B nucleus
1

(ii) any two from:

two required for 1 mark

• P

• R

• T
accept lower case letters
1

(b) sperm cells need a lot of energy to swim

1
[4]

Q24.
(a) (i) root hair
1

(ii) any two from:

ignore food

• water

• ions / minerals / nutrients / salts / correct named eg nitrates

ignore N,P,K

• oxygen
2

(b) (i) stomata

1

(ii) diffusion
1
[5]

Q25.
(a)
 4 correct = 4 marks
3 correct = 3 marks
2 correct = 2 marks
1 correct = 1 mark
extra line from a structure cancels the mark
4

(b) diffusion
1
[5]

Q26.
(a) (i) C and D
1

(ii) cell wall

1

(b) (i) A
1

(ii) D
1

(c) respiration
1
[5]

Q27.
(a) (i) villus
1

(ii) its outer surface is one cell thick

cancel 1 mark for each extra box ticked
1

it has a large surface area

1

it has good blood supply

1
 (b) diffusion
1
[5]

Q28.
(a) (i) sex cells
1

(ii) chromosomes
1

(b) (i) two

1

(ii) recessive
1

(c) (i) cell membrane

allow membrane
1

(ii) cytoplasm
1

(d) (i) A
1

(ii) B
1
[8]

Q29.
(a) (i) tissue
extra box ticked cancels the mark
1

(ii) organ
extra ring drawn cancels the mark
1

(b) (i) Layer B

each extra box ticked cancels 1 mark
1

Layer C
1

(ii) (contain) chloroplasts / chlorophyll

other parts disqualify
1

(c)
 two correct = 2 marks
one correct = 1 mark
extra line from a part of a cell cancels the mark
2
[7]

Q30.
(a)

1 mark for each correct line

mark each line from left hand box
two lines from left hand box cancels mark for that box
3

(b) energy
 1
[4]

Q31.
(a) (i) capillary
1

(ii) diffusion
1

(b) (i) Z
ignore any names
1

(ii) large / increased surface / area / or to absorb more food or improved diffusion
allow all food absorbed
1
[4]

Q32.
(a) (i) diffusion
1

(ii) A
1

(b) (i) osmosis

1

(ii) R
1
[4]

Q33.
(a) asexual
1

(b) mitosis
1

(c) genes
1
[3]

Q34.
(a) (i) A − (cell) wall
1

B − cytoplasm
1

C − plasmid
1

(ii) bacterium cell has cell wall / no nucleus / no mitochondria / plasmids

present
accept its DNA / genetic material is not enclosed / it has no
 nuclear membrane
it = bacterium cell
accept converse for animal cell
ignore flagella
1

(iii) any one from:

• chloroplast
ignore chlorophyll
• (permanent) vacuole
1

(b) (Long tail) moves the sperm / allows the sperm to swim
1

towards the egg

allow correct reference to other named parts of the female
reproductive system
1

(Mitochondria) release energy (for movement / swimming)

allow supply / produce / provide
1

in respiration
1
[9]

Q35.
(a) (i) C and D
no mark if more than one box is ticked
1

(ii) any one from:

do not allow if other cell parts are given in a list

• (have) cell wall(s)

• (have) vacuole(s)
1

(b) (i) A
apply list principle
1

(ii) D
apply list principle
1

(c) respiration
apply list principle
1
[5]

Q36.
(a) (i) capillary
 1

(ii) diffusion
1

(iii) Carbon low(er) high(er)

dioxide
1

Oxygen high(er) low(er)

1 mark for each correct row

1

(b) (i) red blood cells

1

(ii) haemoglobin
1
[6]

Q37.
(a) comparisons are not required but should be credited
accept a clear indication of the statement even if incomplete

can develop into most other types of cell

1

each cell divides every 30 minutes

1

low chance of rejection by the patient’s immune system

1

(b) any three from:

• cheaper / only costs £1000

this must be comparative
ignore costs £1000

• can collect many (stem) cells

• adults give permission for their own bone marrow to be collected

comparisons are not required but should be credited

• safe
3
[6]

Q38.
(a) B
1

(b) D
1

(c) A
1
 [3]

Q39.

(a)
the shape must be (roughly) circular and not shaded, for the
mark
accept the shape drawn in the key if it is not contradictory
1

(b) dominant
1

(c) (i) a half (50%)

1

(ii) Some of B’s sperm cells have an X chromosome

1
[4]

Q40.
(a) xylem and phloem
either order
allow words ringed in box
allow mis-spelling if unambiguous
1

(b) (i) movement / spreading out of particles / molecules / ions / atoms

ignore names of substances / „gases‟
1

from high to low concentration

accept down concentration gradient
ignore „along‟ / „across‟ gradient
ignore „with‟ gradient
1

(ii) oxygen / water (vapour)

allow O2 / O2
ignore O2/ O
allow H2O / H2O
ignore H2O
1
[4]

Q41.
(a) (i) fertilisation
1

(ii) in sequence:
accept 1 next to gene, 2 next to chromosome and 3 next to
nucleus in box

1 gene
 2 chromosome
3 nucleus
allow 1 mark for smallest or largest in correct position
2

(iii) DNA
1

(b) (i) On diagram:

tick drawn next to X and / or Y from Parent 1

tick(s) must be totally outside grid squares
allow ticks around “parent ”
extra ticks elsewhere cancel
1

(ii) 0.5 / ½ / 50% / 1:1 / 50:50 / 1 in 2

allow 2/4 / 2 in 4 / 2 out of 4 / „even(s)‟ / „fifty – fifty‟
do not allow 1:2 or „50 / 50‟ or „50 – 50‟
1

2 (out of 4) boxes are XX

or

half of the sperm contain an X-chromosome

allow XY is male and 2 (out of 4) boxes are XY
1
[7]

Q42.
(a) (i) A = cytoplasm
1

B = (cell) membrane
1

(ii) nucleus
accept chromosome / DNA / genes
accept phonetic
1

(b)
 3
[6]

Q43.
(a) (i)
Feature Mitosis Meiosis
only only

Produces new cells during growth and repair

Produces gametes (sex cells)

Produces genetically identical cells

All 3 correct = 2 marks

2 correct = 1 mark

0 or 1 correct = 0 marks
2

(ii) (a man) testis / testes

accept testicle(s)
1

(a woman) ovary / ovaries

do not accept „ova‟ / ovule
1

(b) (i) XY / YX
or
X and Y
1

(ii) XX
or
X and X or 2 X’s
accept X
1

(c) ½ / 0.5 / 50% / 1:1 / 1 in 2

do not accept 1:2 / 50/50
 allow 50:50
allow 2 in 4
1
[7]

Q44.
(a) (i) A = nucleus
1

B = (cell) membrane
1

(ii) any two from:

ignore shape

• no (cell) wall

• no (large / permanent) vacuole

• no chloroplasts / chlorophyll
2

(b) because high to low oxygen / concentration or down gradient

allow „more / a lot of oxygen molecules outside‟
ignore along / across gradient
1

(c) a tissue
1
[6]

Q45.
(a) mitosis
extra box ticked negates mark
1

(b) cell division is uncontrolled

extra box ticked negates mark
1

(c) any one from:

• smoking / tar
• alcohol
• carcinogens
allow named chemical
• viruses (living in cells)
• (ionising) radiation
accept UV / X-rays / gamma waves
1

(d) bar plotted at 78%

ignore width of bar
1

(e) testicular
extra box ticked negates mark
 1

(f) prostate
extra box ticked negates mark
1

(g) any two from:

• improved treatment / drugs

• earlier diagnosis
• more cancer screening
• improved patient knowledge (of risk factors)
allow improved patient diet / lifestyle
2
[8]

Q46.
(a) A = nucleus
allow phonetic spelling
1

B = (cell) membrane
1

(b) for repair / growth or to replace cells

ignore new cells / skin
1

(c) (i) embryos

1

(ii) paralysis
1
[5]

Q47.
(a) animal cells also have cell membrane
1

(b) 1945–1955
allow 1946–1956
or 1947–1957
1

(c)
allow 9.09 (%) or 9 (%) with no working shown for 1 mark
1

9.1 (%)
allow 9.1 (%) with no working shown for 2 marks
1

(d)
More likely Less likely

✔
 ✔

✔
allow 3 marks for 4 correct
allow 2 marks for 3 correct
allow 1 mark for 2 correct
4
more than one tick in a row negates a mark
[8]

Q48.
(a) (i) A = (cell) membrane
1

B = cytoplasm
do not accept cytoplast
1

(ii) To control the activities of the cell

1

(b)

extra lines cancel

3
[6]

Q49.
(a)
Organ
Structure Organ Tissue
system

Stomach
 Cells lining the
stomach

Mouth, oesophagus,
stomach, liver,
pancreas, small and
large intestine

all 3 correct = 2 marks

2 correct = 1 mark
1 or 0 correct = 0 marks
2

(b) (i) diffusion

allow phonetic spelling
1

(ii) glucose
1

(iii) mitochondria
1
[5]

Q50.
(a) (i) water / H2O
accept oxygen
allow H2O
do not allow H2O or H2O
1

(ii) the mineral ions are absorbed by active transport

1

the absorption of mineral ions needs energy

1

(iii) have (many root) hairs

1

(which) give a large surface area (for absorption)

1

(b) carbon dioxide in

or
oxygen out
or

control water loss

accept gas exchange
ignore gases in and out
ignore gain / lose water
1

(c) (i) guard cells

1

(ii) (stomata are) closed

 allow there is no gap / space
1

(iii) plant will wilt / droop

ignore die
1
[9]

Q51.
(a) (i) alveoli / alveolus
allow air sacs
allow phonetic spelling
1

(ii) any one from:

• protection (of lungs / heart)
• help you breathe / inflate lungs.
1

(b) (i) diffusion

1

(ii) capillaries
1

(iii) any two from:

• (have many) alveoli
allow air sacs
• large surface / area
• thin (exchange) surface or short diffusion pathway
accept only one / two cell(s) thick
• good blood supply / many capillaries
allow (kept) ventilated or maintained concentration gradient.
2
[6]

Q52.
(a)

(b) (trachea) has mucus

1
 to trap pathogens
1

(trachea) has cilia

1

to move mucus out of trachea

1

(c) dependent variable:

number of times mosquitoes landed on socks
1

control variable:
any one from:

• number of mosquitoes in each container

• length of time socks worn
• dampness of socks
• same type of socks
• size of container
• time
• temperature
• species of mosquito
• age of mosquito
1

(d) use worn socks

or
use chemical from worn socks
1

to attract / trap infected mosquitoes

1
or accept:
wear clean socks / change socks regularly (1)
to reduce the chance of attracting mosquitoes (1)

(e) less chlorophyll present

1

(so) less light absorbed

1

(so) reduced photosynthesis

or
(so) less sugar / food made
1
[14]