Material Safety Data Sheet

Ethyl Acetate, OmniSolv ® , For Gas Chromatography, Residue Analysis, HPLC,

Spectrophotometry

1. Product and company identification

Product name : Ethyl Acetate, OmniSolv ® , For Gas Chromatography, Residue Analysis, HPLC,
Spectrophotometry
Product code : EX0241
Supplier : EMD Chemicals Inc.
480 S. Democrat Rd.
Gibbstown, NJ 08027
856-423-6300 Technical Service
Monday-Friday: 8:00 -5:00 PM
Synonym : Ethyl Ethanoate
Material uses : Other non-specified industry: Analytical reagent.
Validation date : 2/12/2009.
In case of emergency : 800-424-9300 CHEMTREC (USA)
613-996-6666 CANUTEC (Canada)
24 Hours/Day: 7 Days/Week

2. Hazards identification
Emergency overview : WARNING!
CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION.
FLAMMABLE LIQUID AND VAPOR.
VAPOR MAY CAUSE FLASH FIRE.
MAY BE HARMFUL IF SWALLOWED.
MAY CAUSE DAMAGE TO THE FOLLOWING ORGANS: KIDNEYS, LIVER,
RESPIRATORY TRACT, SKIN, EYES.
MAY BE HARMFUL IF INHALED.
Keep away from heat, sparks and flame. Do not ingest. Avoid breathing vapor or mist.
Avoid contact with eyes, skin and clothing. Use only with adequate ventilation. Keep
container tightly closed and sealed until ready for use. Wash thoroughly after handling.
Physical state : Liquid. [Colorless.]
OSHA/HCS status : This material is considered hazardous by the OSHA Hazard Communication Standard
(29 CFR 1910.1200).
Routes of entry : Dermal contact. Eye contact. Inhalation. Ingestion.
Potential acute health effects
Inhalation : Irritating to respiratory system. May be harmful if inhaled.
Ingestion : May be harmful if swallowed.
Skin : Irritating to skin.
Eyes : Irritating to eyes.
Potential chronic health effects
Carcinogenicity :No known significant effects or critical hazards.
Mutagenicity :No known significant effects or critical hazards.
Teratogenicity :No known significant effects or critical hazards.
Developmental effects :No known significant effects or critical hazards.
Fertility effects :No known significant effects or critical hazards.
Target organs :May cause damage to the following organs: kidneys, liver, upper respiratory tract, skin,
eyes.
Medical conditions : Pre-existing disorders involving any target organs mentioned in this MSDS as being at
aggravated by over- risk may be aggravated by over-exposure to this product.
exposure
See toxicological information (section 11)

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 Ethyl Acetate, OmniSolv ® , For Gas EX0241 2/8
Chromatography, Residue Analysis,
HPLC, Spectrophotometry

3. Composition/information on ingredients
Name CAS number % by weight
Ethyl Acetate 141-78-6 100

4. First aid measures

Eye contact : Check for and remove any contact lenses. Immediately flush eyes with plenty of water
for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical
attention immediately.
Skin contact : In case of contact, immediately flush skin with plenty of water for at least 15 minutes
while removing contaminated clothing and shoes. Wash clothing before reuse. Clean
shoes thoroughly before reuse. Get medical attention immediately.
Inhalation : Move exposed person to fresh air. If not breathing, if breathing is irregular or if
respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel.
Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention
immediately.
Ingestion : Wash out mouth with water. Do not induce vomiting unless directed to do so by medical
personnel. Never give anything by mouth to an unconscious person. Get medical
attention immediately.

5. Fire-fighting measures
Flammability of the product : Flammable liquid. In a fire or if heated, a pressure increase will occur and the container
may burst, with the risk of a subsequent explosion. The vapor/gas is heavier than air
and will spread along the ground. Vapors may accumulate in low or confined areas or
travel a considerable distance to a source of ignition and flash back. Runoff to sewer
may create fire or explosion hazard.
Extinguishing media : Use dry chemical, CO2, water spray (fog) or foam.
Not suitable : Do not use water jet.
Special exposure hazards : Promptly isolate the scene by removing all persons from the vicinity of the incident if
there is a fire. No action shall be taken involving any personal risk or without suitable
training. Move containers from fire area if this can be done without risk. Use water
spray to keep fire-exposed containers cool.
Hazardous thermal : Decomposition products may include the following materials:
decomposition products carbon dioxide
carbon monoxide
Special protective : Fire-fighters should wear appropriate protective equipment and self-contained breathing
equipment for fire-fighters apparatus (SCBA) with a full face-piece operated in positive pressure mode.
Special remarks on fire : Vapor may travel a considerable distance to source of ignition and flash back.
hazards

6. Accidental release measures

Personal precautions : No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
entering. Do not touch or walk through spilled material. Shut off all ignition sources. No
flares, smoking or flames in hazard area. Avoid breathing vapor or mist. Provide
adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put
on appropriate personal protective equipment (see section 8).
Environmental precautions : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
Methods for cleaning up

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 Ethyl Acetate, OmniSolv ® , For Gas EX0241 3/8
Chromatography, Residue Analysis,
HPLC, Spectrophotometry

6. Accidental release measures

Spill : Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas.
Contain and collect spillage with non-combustible, absorbent material e.g. sand, earth,
vermiculite or diatomaceous earth and place in container for disposal according to local
regulations (see section 13). Use spark-proof tools and explosion-proof equipment.
Dispose of via a licensed waste disposal contractor. Contaminated absorbent material
may pose the same hazard as the spilled product. Note: see section 1 for emergency
contact information and section 13 for waste disposal. Dilute with water and mop up if
water-soluble or absorb with an inert dry material and place in an appropriate waste
disposal container.

7. Handling and storage

Handling : Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing vapor or mist.
Use only with adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Do not enter storage areas and confined spaces unless adequately
ventilated. Keep in the original container or an approved alternative made from a
compatible material, kept tightly closed when not in use. Store and use away from heat,
sparks, open flame or any other ignition source. Use explosion-proof electrical
(ventilating, lighting and material handling) equipment. Use non-sparking tools. Take
precautionary measures against electrostatic discharges. To avoid fire or explosion,
dissipate static electricity during transfer by grounding and bonding containers and
equipment before transferring material. Empty containers retain product residue and
can be hazardous. Do not reuse container.
Storage : Store in accordance with local regulations. Store in a segregated and approved area.
Store in original container, protected from direct sunlight. Eliminate all ignition sources.
Separate from oxidizing materials. Keep container tightly closed and sealed until ready
for use. Containers that have been opened must be carefully resealed and kept upright
to prevent leakage.

8. Exposure controls/personal protection

Ingredient Exposure limits
Ethyl Acetate ACGIH TLV (United States, 1/2008).
TWA: 400 ppm 8 hour(s).
TWA: 1440 mg/m³ 8 hour(s).
OSHA PEL 1989 (United States, 3/1989).
TWA: 400 ppm 8 hour(s).
TWA: 1400 mg/m³ 8 hour(s).
NIOSH REL (United States, 6/2008).
TWA: 400 ppm 10 hour(s).
TWA: 1400 mg/m³ 10 hour(s).
OSHA PEL (United States, 11/2006).
TWA: 400 ppm 8 hour(s).
TWA: 1400 mg/m³ 8 hour(s).

Consult local authorities for acceptable exposure limits.

Engineering measures : Use only with adequate ventilation. Use process enclosures, local exhaust ventilation or
other engineering controls to keep worker exposure to airborne contaminants below any
recommended or statutory limits. The engineering controls also need to keep gas, vapor
or dust concentrations below any lower explosive limits. Use explosion-proof ventilation
equipment.
Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period. Appropriate
techniques should be used to remove potentially contaminated clothing. Wash
contaminated clothing before reusing. Ensure that eyewash stations and safety showers
are close to the workstation location.
Personal protection

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 Ethyl Acetate, OmniSolv ® , For Gas EX0241 4/8
Chromatography, Residue Analysis,
HPLC, Spectrophotometry

8. Exposure controls/personal protection

Respiratory : Use a properly fitted, air-purifying or air-fed respirator complying with an approved
standard if a risk assessment indicates this is necessary. Respirator selection must be
based on known or anticipated exposure levels, the hazards of the product and the safe
working limits of the selected respirator.
Hands : Chemical-resistant, impervious gloves complying with an approved standard should be
worn at all times when handling chemical products if a risk assessment indicates this is
necessary. Recommended: butyl rubber
Eyes : Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists or
dusts. Recommended: splash goggles
Skin : Personal protective equipment for the body should be selected based on the task being
performed and the risks involved and should be approved by a specialist before handling
this product.
Recommended: lab coat
Environmental exposure : Emissions from ventilation or work process equipment should be checked to ensure they
controls comply with the requirements of environmental protection legislation. In some cases,
fume scrubbers, filters or engineering modifications to the process equipment will be
necessary to reduce emissions to acceptable levels.

9. Physical and chemical properties

Physical state : Liquid. [Colorless.]
Flash point : Closed cup: -5.15°C (22.7°F)
Auto-ignition temperature : 425.85°C (798.5°F)
Flammable limits : Lower: 2%
Upper: 11.5%
Color : Colorless.
Odor : Characteristic. Sweetish
Molecular weight : 88.12 g/mole
Molecular formula : C4-H8-O2
pH : Not available.
Boiling/condensation point : 77.2°C (171°F)
Melting/freezing point : -84°C (-119.2°F)
Critical temperature : 249.9°C (481.8°F)
Relative density : 0.902
Vapor pressure : Not available.
Vapor density : 3 [Air = 1]
Odor threshold : 1 ppm
Evaporation rate : 4.94 compared with (n-BUTYL ACETATE=1)
Solubility : Partially soluble in the following materials: water

10 . Stability and reactivity

Chemical stability : The product is stable.
Possibility of hazardous : Under normal conditions of storage and use, hazardous reactions will not occur.
reactions
Hazardous polymerization : Under normal conditions of storage and use, hazardous polymerization will not occur.
Conditions to avoid : Avoid all possible sources of ignition (spark or flame). Do not pressurize, cut, weld,
braze, solder, drill, grind or expose containers to heat or sources of ignition. Do not
allow vapor to accumulate in low or confined areas.
Materials to avoid : Reactive or incompatible with the following materials:
oxidizing materials

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 Ethyl Acetate, OmniSolv ® , For Gas EX0241 5/8
Chromatography, Residue Analysis,
HPLC, Spectrophotometry

10 . Stability and reactivity

Hazardous decomposition : Under normal conditions of storage and use, hazardous decomposition products should
products not be produced.
Conditions of reactivity : Highly flammable in the presence of the following materials or conditions: open flames,
sparks and static discharge, heat, shocks and mechanical impacts and oxidizing
materials.
Vapor may travel a considerable distance to source of ignition and flash back.

Highly explosive in the presence of the following materials or conditions: open flames,
sparks and static discharge, heat, shocks and mechanical impacts and oxidizing
materials.

11 . Toxicological information
Acute toxicity
Product/ingredient name Test Route Species Result
Ethyl Acetate LD50 Dermal Rabbit >20 mL/kg
LD50 Oral Mouse 4100 mg/kg
LD50 Oral Rat 5620 mg/kg
LD50 Oral Rabbit 4935 mg/kg
LDLo Rat 5 g/kg
Subcutaneous
LC50 Inhalation Rat 1600 ppm
Gas.
LC50 Inhalation Rat >6000 ppm
Gas.
Carcinogenicity
Classification
Product/ingredient name ACGIH IARC EPA NIOSH NTP OSHA
Ethyl Acetate A4 - - - - -
No known significant effects or critical hazards.
Mutagenicity
No known significant effects or critical hazards.
Teratogenicity
No known significant effects or critical hazards.

12 . Ecological information
Aquatic ecotoxicity
Product/ingredient name Result Species Exposure
Ethyl Acetate Acute EC50 5600 mg/L Algae 48 hours
Acute EC50 3300 mg/L Algae 48 hours
Acute EC50 260 mg/L Fish 48 hours
Acute LC50 425.3 mg/L Fish 96 hours
Acute LC50 484 mg/L Fish 96 hours
Acute LC50 230 mg/L Fish 96 hours
Acute LC50 560000 ug/L Daphnia - Water flea - 48 hours
Fresh water Daphnia magna - <1 days
Acute LC50 484000 to Fish - Rainbow 96 hours
602000 ug/L Fresh water trout,donaldson trout -
Oncorhynchus mykiss -
Juvenile (Fledgling,
Hatchling, Weanling)
Acute LC50 425300 to Fish - Rainbow 96 hours
500000 ug/L Fresh water trout,donaldson trout -
Oncorhynchus mykiss -
Juvenile (Fledgling,

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 Ethyl Acetate, OmniSolv ® , For Gas EX0241 6/8
Chromatography, Residue Analysis,
HPLC, Spectrophotometry

12 . Ecological information
Hatchling, Weanling)
Acute LC50 295000 ug/L Daphnia - Water flea - 48 hours
Fresh water Daphnia pulex - <1 days
Acute LC50 230000 to Fish - Fathead minnow - 96 hours
250000 ug/L Fresh water Pimephales promelas - 29 to
30 days - 18.2 mm - 0.106 g
Acute LC50 230000 ug/L Daphnia - Water flea - 48 hours
Fresh water Daphnia pulex - <1 days
Acute LC50 212500 to Fish - Indian catfish - 96 hours
225420 ug/L Fresh water Heteropneustes fossilis -
14.16 cm - 25.54 g
Acute LC50 175000 ug/L Daphnia - Water flea - 48 hours
Fresh water Daphnia cucullata - 11 days
Acute LC50 154000 ug/L Daphnia - Water flea - 48 hours
Fresh water Daphnia cucullata - 11 days
Acute LC50 1600000 ug/L Crustaceans - Aquatic 48 hours
Fresh water sowbug - Asellus aquaticus
Acute LC50 819000 ug/L Daphnia - Water flea - 48 hours
Fresh water Daphnia magna - <1 days
Acute LC50 786000 ug/L Daphnia - Water flea - 48 hours
Fresh water Daphnia magna - <1 days
Acute LC50 778000 ug/L Daphnia - Water flea - 48 hours
Fresh water Daphnia magna - <1 days
Acute LC50 698000 ug/L Daphnia - Water flea - 48 hours
Fresh water Daphnia magna - <1 days
Acute LC50 660000 ug/L Daphnia - Water flea - 48 hours
Fresh water Daphnia magna - <1 days
Environmental effects : No known significant effects or critical hazards.
Other adverse effects : No known significant effects or critical hazards.

13 . Disposal considerations
The information presented only applies to the material as supplied. The identification based on characteristic(s) or listing
may not apply if the material has been used or otherwise contaminated. It is the responsibility of the waste generator to
determine the toxicity and physical properties of the material generated to determine the proper waste identification and
disposal methods in compliance with applicable regulations. Disposal should be in accordance with applicable regional,
national and local laws and regulations.

14 . Transport information
Regulatory UN number Proper shipping Classes PG* Label Additional
information name information
DOT Classification UN1173 ETHYL ACETATE 3 II Reportable quantity
FLAMMABLE LIQUID
5000 lbs. (2270 kg)
3

PG* : Packing group

15 . Regulatory information
United States
HCS Classification : Flammable liquid
Irritating material
Target organ effects
U.S. Federal regulations : TSCA 4(a) final test rules: Ethyl Acetate
United States inventory (TSCA 8b): This material is listed or exempted.
TSCA 12(b) one-time export: Ethyl Acetate
TSCA (Toxic Substance Control Act): This product is listed on the TSCA Inventory.
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 Ethyl Acetate, OmniSolv ® , For Gas EX0241 7/8
Chromatography, Residue Analysis,
HPLC, Spectrophotometry

15 . Regulatory information
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: Ethyl Acetate
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: Ethyl
Acetate : Fire hazard, Immediate (acute) health hazard, Delayed (chronic) health hazard
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean Air Act (CAA) 112 accidental release prevention: No products were found.

Clean Air Act (CAA) 112 regulated flammable substances: No products were found.
Clean Air Act (CAA) 112 regulated toxic substances: No products were found.
DEA List I Chemicals : Not listed
(Precursor Chemicals)
DEA List II Chemicals : Not listed
(Essential Chemicals)
Massachusetts Substances : This material is listed.
New Jersey Hazardous : This material is listed.
Substances
New York Acutely : This material is listed.
Hazardous Substances
Pennsylvania RTK : This material is listed.
Hazardous Substances
Canada
WHMIS (Canada) : Class B-2: Flammable liquid
Class D-2B: Material causing other toxic effects (Toxic).
Canadian lists : CEPA Toxic substances: This material is not listed.
Canadian ARET: This material is not listed.
Canadian NPRI: This material is listed.
Alberta Designated Substances: This material is not listed.
Ontario Designated Substances: This material is not listed.
Quebec Designated Substances: This material is not listed.
CEPA DSL / CEPA NDSL : This material is listed or exempted.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the
MSDS contains all the information required by the Controlled Products Regulations.
EU regulations
Hazard symbol or symbols :

Risk phrases : R11- Highly flammable.

R36- Irritating to eyes.
R66- Repeated exposure may cause skin dryness or cracking.
R67- Vapors may cause drowsiness and dizziness.
Safety phrases : S2- Keep out of the reach of children.
S16- Keep away from sources of ignition - No smoking.
S26- In case of contact with eyes, rinse immediately with plenty of water and seek
medical advice.
S33- Take precautionary measures against static discharges.
International regulations

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 Ethyl Acetate, OmniSolv ® , For Gas EX0241 8/8
Chromatography, Residue Analysis,
HPLC, Spectrophotometry

15 . Regulatory information
International lists : Australia inventory (AICS): This material is listed or exempted.
China inventory (IECSC): This material is listed or exempted.
Japan inventory (ENCS): This material is listed or exempted.
Japan inventory (ISHL): Not determined.
Korea inventory (KECI): This material is listed or exempted.
New Zealand Inventory of Chemicals (NZIoC): This material is listed or exempted.
Philippines inventory (PICCS): This material is listed or exempted.

16 . Other information
National Fire Protection :
Association (U.S.A.)

3 Flammability
Health 1 0 Instability
Special

Notice to reader
The statements contained herein are based upon technical data that EMD Chemicals Inc. believes to be reliable,
are offered for information purposes only and as a guide to the appropriate precautionary and emergency handling
of the material by a properly trained person having the necessary technical skills. Users should consider these
data only as a supplement to other information gathered by them and must make independent determinations of
suitability and completeness of information from all sources to assure proper use, storage and disposal of these
materials and the safety and health of employees and customers and the protection of the environment. EMD
CHEMICALS INC. MAKES NO REPRESENTATION OR WARRANTY OF ANY KIND, EXPRESS OR IMPLIED,
INCLUDING MERCHANTABILITY OR FITNESS FOR A PARTICULAR USE, WITH RESPECT TO THE INFORMATION
HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS.