1. Match the list I with list II.

3) B, C and D only
List I List II 4) A, B, C, D and E (NEET 2024)

A Two or more alternative I Back 4. Match List I with List II.

forms of a gene cross
List I List II
B Cross of F1 progeny with II Ploidy
A Down’s I 11th chromosome
homozygous recessive
syndrome
parent
B 𝛼- II ‘X’ chromosome
C Cross of F1 progeny with III Allele
Thalassemia
any of the parents
C 𝛽- III 21st chromosome
D Number of chromosome IV Test
Thalassemia
sets in plant cross
D Klinefelter's IV 16th chromosome
Choose the correct answer from the options syndrome
given below:
1) A-I, B-II, C-III, D-IV Choose the correct answer from the options
2) A-II, B-I, C-III, D-IV given below:
3) A-III, B-IV, C-I, D-II 1) A-I, B-II, C-III, D-IV
4) A-IV, B-III, C-II, D-I (NEET 2024) 2) A-II, B-III, C-IV, D-I
3) A-III, B-IV, C-I, D-II
2. In a plant, black seed color (BB/Bb) is 4) A-IV, B-I, C-II, D-III (NEET 2024)
dominant over white seed color (bb). In order
to find out the genotype of the black seed 5. As per ABO blood grouping system, the blood
plant, with which of the following genotype group of father is B+ ,mother is A+ and child is
will you cross it? O+. Their respective genotype can be
1) BB A. IBi / IAi / ii
2) bb B. IB IB / IAIA / ii
3) Bb C. IA IB / iIA / IBi
4) BB/Bb (NEET 2024) D. IAi / IBi / IAi
E. iIB / iIA / IA IB
3. Which one of the following can be explained Choose the most appropriate answer from
on the basis of Mendel's Law of Dominance? the options given below:
A. Out of one pair of factors one is 1) A only
dominant and the other is recessive. 2) B only
B. Alleles do not show any expression and 3) C & B only
both the characters appear as such in F2 4) D & E only (NEET 2024)
generation.
C. Factors occur in pairs in normal diploid 1. The phenomenon of pleiotropism refers to
plants. 1) Presence of two alleles, each of the two
D. The discrete unit controlling a particular genes controlling a single trait.
character is called factor. 2) A single gene affecting multiple
E. The expression of only one of the phenotypic expression.
parental characters is found in a 3) More than two genes affecting a single
monohybrid cross. character.
Choose the correct answer from the 4) Presence of several alleles of a single
options given below: gene controlling a single crossover
1) A, B and C only
2) A, C, D and E only (NEET 2023)
2. Frequency of recombination between gene 1. XO Type of sex determination can be found
pairs on same chromosome as a measure of in :
the distance between genes to map their 1) Drosophila
position of on chromosome, was used for the 2) Birds
first time by 3) Grasshoppers
1) Sutton and Boveri 4) Monkeys (NEET 2022)
2) Alfred Sturtevant
3) Henking 2. Given below are two statements
4) Thomas Hunt Morgan (NEET 2023) Statement I: Mendel studied seven pairs of
contrasting traits in pea plants and proposed
3. Which of the following statements are the Laws of Inheritance.
correct about Klinefelter's Syndrome? Statement II: Seven characters examined by
A. This disorder was first described by Mendel in his experiment on pea plants were
Langdon Down (1866). seed shape and colour, flower colour, pod
B. Such an individual has overall masculine shape and colour, flower position and stem
development. However, the feminine height.
development is also expressed. In the light of the above statements, choose
C. The affected individual is short statured. the correct answer from the options given
D. Physical, psychomotor and mental below:
development is retarded. 1) Both Statement I and Statement II are
E. Such individuals are sterile. correct
2) Both Statement I and Statement II are
Choose the correct answer from the options incorrect
given below: 3) Statement I is correct but Statement II is
1) C and D only incorrect
2) B and E only 4) Statement I is incorrect but Statement II
3) A and E only is correct
4) A and B only (NEET 2022)
(NEET 2023)
3. Which of the following occurs due to the
4. Broad palm with single palm crease is visible presence of autosome linked dominant trait?
in a person suffering from 1) Sickle cell anaemia
1) Turner’s syndrome 2) Myotonic dystrophy
2) Klinefelter’s syndrome 3) Hemophilia
3) Thalassemia 4) Thalassemia
4) Down’s syndrome (NEET 2022)
(NEET 2023)
4. Given below are two statements: one is
5. Which one of the following symbols labelled as Assertion (A) and the other is
represents mating between relatives in labelled as Reason (R)
human pedigree analysis? Assertion (A) : Mendel’s law of Independent
assortment does not hold good for the genes
that are located closely on the same
(1) chromosome.
Reason (R) : Closely located genes assort
independently.
(3) In the light of the above statements , chose
the correct answer dorm the option given
below;
(NEET 2023) 1) Both (A) and ( R ) are correct and (R ) is
correct explanation of (A)
 2) Both (A) and (R) are correct but (R) is not 5. How many pairs of contrasting characters in
the correct explanation of (A) pea plants were studied by Mendel in his
3) (A) is correct but (R) is not correct experiments?
4) (A) is not correct but (R) is correct a) Eight
(NEET 2022) b) Seven
c) Five
5. If a colour blind female marries a man whose d) Six
mother was also colour blind, what are the (2015 Cancelled)
chances of her progeny having colour
blindness ? 6. Which one of the following traits of garden
1) 25% pea studied by Mendel was a recessive
2) 50% feature?
3) 75% a) Axial flower position
4) 100% (NEET 2022) b) Green seed colour
c) Green pod colour
Mendel’s Laws of inheritance d) Round seed shape
1. How many true breeding pea plant varieties (2003)
did Mendel select as pairs, which were
similar except in one character with 7. The genes controlling the seven pea
contrasting traits? characters studied by Mendel are now
a) 4 known to be located on how many different
b) 2 chromosomes?
c) 14 a) Seven
d) 8 (NEET 2020) b) Six
c) Five
2. Among the following characters, which one d) Four (2003)
was not considered by Mendel in his
experiments on pea? 8. According to Mendelism , which character
a) Trichomes – Glandular or non-glandular shows dominance?
b) Seed – Green or yellow a) Terminal position of flower
c) Pod – Inflated or constricted b) Green colour in seed coat
d) Stem– Tall or dwarf c) Wrinkled seeds
(NEET 2017) d) Green pod colour
(2000)
3. Which one from those given below is the
period for Mendel’s hybridization 9. First geneticist/father of genetics was
experiments? a) De Vries
a) 1840-1850 b) Mendel
b) 1857-1869 c) Darwin
c) 1870-1877 d) Morgan
d) 1856-1863 (NEET 2017) (1991)

4. In his classic experiments on pea plants, 10. which contribute to the success of Mendel?
Mendel did not use a) Qualitative analysis of data
a) seed shape b) Observation of distinct inherited traits
b) flower position c) His knowledge of biology
c) seed colour d) Consideration of one character at one
d) pod length time.
(2015) (1988)
Inheritance of One Gene b) 4 genotypes; 3 phenotypes
11. The production of gametes by the parents, c) 4 genotypes; 4 phenotypes
formation of zygotes, the F1 and F2 plants, can d) 3 genotypes; 3 phenotypes
be understood from a diagram called (NEET 2017)
a) net square
b) bullet square 16. A tall true breeding garden pea plant is
c) punch square crossed with a dwarf true breeding garden
d) Punnett square pea plant. When the F1 plants were selfed
(NEET 2021) the resulting genotypes were in the ratio of
a) 3:1 : : Tall : Dwarf
12. In a cross between a male and female, both b) 3:1 : : Dwarf : Tall
heterozygous for sickle cell anaemia gene, c) 1 : 2 : 1 : : Tall homozygous : Tall
what percentage of the progeny will be heterozygous : Dwarf
diseased? d) 1 : 2 : 1 : : Tall heterozygous : Tall
a) 100% homozygous : Dwarf
b) 50% (NEET-I 2016)
c) 75%
d) 25% (NEET 2021) 17. A gene showing co-dominance has
a) alleles that are recessive to each other
13. Identify the wrong statement with reference b) both alleles independently expressed in
to the gene ‘I’ that controls ABO blood the heterozygote
groups. c) one allele dominant on the other
a) The gene(I) has three alleles. d) alleles tightly linked on the same
b) A person will have only two of the three chromosome.
alleles. (2015)
c) When IA and IB are present together, they 18. Alleles are
express same type of sugar. a) different molecular forms of a gene
d) Allele i does not produce any sugar. b) heterozygotes
(NEET 2020) c) different phenotype
d) true breeding homozygotes.
14. In Antirrhinum (snapdragon), a red flower (2015 Cancelled)
was crossed with a white flower and in F1
generation all pink flowers were obtained. 19. Multiple alleles are present
When pink flowers were selfed, the F2 a) at the same locus of the chromosome
generation showed white , red and pink b) on non-sister chromatids
flowers. Choose the incorrect statements c) on different chromosomes
from the following. d) at different loci on the same
a) Law of segregation does not apply in this chromosome
experiment (2015 Cancelled)
b) This experiment does not follow the
principle of dominance 20. A man with blood group ’A’ marries a woman
c) Pink colour in F1 is due to incomplete with blood group ‘B’. What are all the
dominance possible blood groups of their offspring?
! # ! a) A , B , AB and O
d) Ratio of F2 is " (red) : " (pink) : " (white).
(NEET 2019) b) O only
c) A and B only
15. The genotypes of a husband and wife are IA IB d) A , B and AB only
and IA i . Among the blood types of their (2015 Cancelled)
children, how many different genotypes and
phenotypes are possible? 21. If two person with ‘AB’ blood group marry
a) 3 genotypes; 4 phenotypes and have sufficiently large number of
 children, these children could be classified as 26. ABO blood groups in humans are controlled
‘A’ blood group: ‘AB’ blood group: ‘B’ blood by the gene I . It has three alleles-IA,IB and i .
group in 1:2:1 ratio. Modern technique of Since there are three different alleles, six
protein electrophoresis reveals presence of different genotypes are possible. How many
both ‘A’ and ‘B’ type protein in ‘AB’ blood phenotypes can occur?
group individuals. This in an example of a) Three
a) partial dominance b) One
b) complete dominance c) Four
c) codominance d) Two (2010)
d) incomplete dominance
(NEET 2013) 27. The genotype of a plant showing the
dominant phenotype can be determined by
22. Which idea is depicted by a cross in which a) test cross
the f1 generation resembles both the b) dihybrid cross
parents? c) pedigree analysis
a) Inheritance of one gene d) back cross (2010)
b) Co-dominance
c) Incomplete dominance 28. Which one of the following cannot be
d) Complete dominance explained on the basis of Mendel’s law of
(NEET 2013) dominance?
a) The discrete unit controlling a particular
23. F2 generation in a mendelian cross showed character is called a factor.
that both genotypic and phenotypic ratios b) Out of one pair of factors one is
are same as 1:2:1 . It represents a case of dominant, and the other recessive.
a) co-dominance c) Alleles do not show any blending and
b) dihybrid cross both the characters recover as such in F2
c) monohybrid cross with complete generation
dominance d) Factors occur in pairs.
d) monohybrid cross with incomplete (2010)
dominance
(2012) 29. ABO blood grouping is controlled by gene I
which has three alleles and show co-
24. A test cross is carried out to dominance. There are six genotypes. How
a) determine the genotype of a plant at F2 many phenotypes in all are possible?
b) predict whether two traits are linked a) Six
c) assess the number of alleles of a gene b) Three
d) determine whether two species or c) Four
varieties will breed successfully. d) Five (Mains 2010)
(Mains 2012)
30. A cross in which an organism showing a
25. Test cross in plants or in Drosophila involves dominant phenotype is crossed with the
crossing recessive parent in order to know its
a) between two genotypes with recessive genotype is called
trait a) monohybrid cross
b) between two F1 hybrids b) back cross
c) the F1 hybrid with a double recessive c) test cross
genotype d) dihybrid cross. (Mains 2010)
d) between two genotypes with dominant
trait. 31. In Antirrhinum two plants with pink flowers
(Mains 2011) were hybridized. The F1 plants produced red,
pink and white flowers in the proportion of 1
 red, 2 pink and 1 white. What could be the a) it expresses its effect only in homozygous
genotype of the two plants used for state
hybridisation? Red flower colour is b) it expresses its effect only in
determined by RR and white by rr genes. heterozygous condition
a) rrrr c) it expresses its effect both in
b) RR homozygous and heterozygous condition
c) Rr d) it never expresses its effect in any
d) rr (Mains 2010) condition (2002)

32. In pea plants yellow seeds are dominant to 37. When dominant and recessive alleles express
green. If a heterozygous yellow seeded plant itself together it is called
is crossed with a green seeded plant, what a) co-dominance
ratio of yellow and green seeded plants b) dominance
would you expect in F1 generation? c) amphidominance
a) 9:1 d) pseudodominance (2001)
b) 1:3
c) 3:1 38. In hybridisation, Tt × tt gives rise to the
d) 50:50 (2007) progeny of ratio
a) 2:1
33. A common test to find the genotype of a b) 1:2:1
hybrid is by c) 1:1
a) crossing of one F2 progeny with female d) 1:2 (1999)
parent
b) studying the sexual behaviour of F1 39. A child’s blood group is ‘O’. The parent’s
progenies blood groups cannot be
c) crossing of one F1 progeny with male a) A and B
parent b) A and A
d) crossing of one F2 progeny with male c) AB and O
parent d) B and O (1994)
(2007)
40. A child of O-group has B-group father. The
34. Test cross involves genotype of father will be
a) crossing between two genotypes with a) IOIO
dominant trait b) IBIB
b) crossing between two genotypes with c) IAIB
recessive trait d) IBIO (1992)
c) crossing between two F1 hybrids
d) crossing the F1 hybrid with a double 41. An allele is dominant if it is expressed in
recessive genotype. a) Both homozygous and heterozygous
(2006) states
b) Second generation
35. Phenotype of an organism is the result of c) Heterozygous combination
a) Genotype and environment interactions d) Homozygous combination
b) Mutations and linkages (1992)
c) Cytoplasmic effects and nutrition
d) Environmental changes and sexual 42. An organism with two identical alleles is
dimorphism. a) dominant
(2006) b) hybrid
c) heterozygous
36. A gene is said to be dominant if d) homozygous
(1992)
43. A man of A-blood group marries a woman of d) epistasis. (1990)
AB blood group. Which type of progeny
would indicate that man is heterozygous A? 50. tt mates with Tt. What will be characteristic
a) AB of offspring?
b) A a) 75% recessive
c) O b) 50% recessive
d) B (1991) c) 25% recessive
d) All dominant (1990)
44. Multiple alleles control inheritance of
a) phenylketonuria 51. Haploids are able to express both recessive
b) colour blindness and dominant alleles/mutations because
c) sickle cell anaemia there are
d) blood groups a) many alleles for each gene
(1991) b) two alleles for each gene
c) only one allele for each gene in the
45. The contrasting pairs of factors in mendelian individual
crosses are called d) only one allele in a gene (1988)
a) multiple alleles
b) allelomorphs Inheritance of Two Genes
c) alloloci 52. Experimental verification of the
d) paramorphs. (1991) chromosomal theory of inheritance was done
by
46. Mendel’s last law is a) Mendel
a) segregation b) Sutton
b) dominance c) Boveri
c) independent assortment d) Morgan (NEET 2020)
d) polygenic inheritance (1991)
53. What map unit (centimorgan) is adopted in
47. Blue eye colour is recessive to brown eye the construction of genetic maps?
colour. A brown eyed man whose mother a) A unit of distance between genes on
was blue eyed marries a blue-eyed woman. chromosomes, representing 50% cross
The children will be over.
a) Both blue eyed and brown eyed 1:1 b) A unit of distance between two
b) All brown eyed expressed genes, representing 10% cross
c) All blue eyed over.
d) Blue eyed and brown eyed 3:1 c) A unit of distance between two
(1991) expressed genes, representing 100%
cross over.
48. RR(Red) antirrhinum is crossed with white d) A unit of distance between genes on
(WW) one. Offspring RW are pink. This is an chromosomes, representing 1% cross
example of over. (NEET 2019)
a) dominant-recessive
b) incomplete dominance 54. The frequency of recombination between
c) hybrid gene present on the same chromosome as a
d) supplementary genes. measure of the distance between genes was
(1991) explained by
a) Sutton Boveri
49. ABO blood group system is due to b) T.H. Morgan
a) multifactor inheritance c) Gregon J . Mendel
b) incomplete dominance d) Alfred Sturtevant
c) multiple allelism (NEET 2019)
55. The mechanism that causes a gene to move d) The genes are tightly linked.
from one linkage group to another is called (NEET 2013)
a) inversion
b) duplication 61. When two unrelated individuals or lines are
c) translocation crossed, the performance of F1 hybrid is
d) crossing-over often superior to both its parents. This
(NEET-II 2016) phenomenon is called
a) heterosis
56. In a test cross involving F1 dihybrid flies, more b) transformation
parental-type offspring were produced than c) splicing
the recombinant-type offspring. This d) metamorphosis (2011)
indicates
a) the two genes are linked and present on 62. Select the correct statement from the ones
the same chromosome given below with respect to dihybrid cross.
b) both of the characters are controlled by a) Tightly linked genes on the same
more than one gene chromosomes show higher
c) the two genes are located on two recombinations
different chromosomes b) Genes far apart on the same
d) chromosomes failed to separated during chromosome show very few
meiosis. recombinations
(NEET-I 2016) c) Genes loosely linked on the same
chromosome show similar
57. The term ”linkage” was coined by recombinations.
a) G . Mendel d) Tightly linked genes on the same
b) W . Sutton chromosome show very few
c) T.H. Morgan recombinations
d) T. Boveri (2015) (2010)

58. The movement of a gene from one linkage 63. A human male produces sperms with the
group to another is called genotypes AB, Ab, aB and ab pertaining to
a) translocation two diallelic characters in equal proportions.
b) crossing over What is the corresponding genotype of this
c) inversion person?
d) duplication (2015 Cancelled) a) AaBB
b) AABb
59. Fruit colour in squash is an example of c) AABB
a) recessive epistasis d) AaBb (2007)
b) dominant epistasis
c) complementary genes 64. In Mendel’s experiments with garden pea,
d) inhibitory genes. round seed shape (RR) was dominant over
(2014) wrinkled seeds(rr), yellow cotyledon (YY) was
dominant over green cotyledon (yy). What
60. Which of the following statements is not true are the expected phenotypes in the F2
of two genes that show 50% recombination generations of the cross RRYY × rryy?
frequency? a) Round seeds with yellow cotyledons, and
a) The gene show independent assortment wrinkled seeds with yellow cotyledons
b) If the genes are present on the same b) Only round seeds with green cotyledons
chromosome, they undergo more than c) Only wrinkled seeds with yellow
one cross-overs in every meiosis cotyledons
c) The genes may be on different d) Only wrinkled seeds with green
chromosomes cotyledons (2006)
65. In order to find out the different types of c) non complementary gene
gametes produced by a pea plant having the d) complementary gene
genotype AaBb it should be crossed to a (2001)
plant with the genotype
a) AABB 71. A and B genes are linked. What shall be
b) AaBb genotype of progeny in a cross between
c) aabb AB/ab and ab/ab?
d) aaBB (2005) a) AAbb and aabb
b) AaBb and aabb
66. In a plant, red fruit (R) is dominant over c) AABB and aabb
yellow fruit (r) and tallness (T) is dominant d) None of these (2001)
over shortness (t). If a plant with RRTt
genotype is crossed with a plant that is rrtt, 72. Ratio of complementary genes is
a) 25% will be tall with red fruit a) 9 : 3 : 4
b) 50% will be tall with red fruit b) 12 : 3 : 1
c) 75% will be tall with red fruit c) 9 : 3 : 3 : 4
d) all the offspring will be tall with red fruit d) 9 : 7 (2001)
(2004)
73. Independent assortment of genes does not
67. Lack of independent assortment of two take place when
genes A and B in fruit fly Drosophila is due to a) genes are located on homologous
a) repulsion chromosomes
b) recombination b) genes are linked and located on same
c) linkage chromosome
d) crossing over (2004) c) genes are located on non-homogenous
chromosome
68. Two crosses between the same pair of d) all of these. (2001)
genotypes or phenotypes in which the
sources of the gametes are reversed in one 74. Due to the cross between TTRr × ttrr the
cross, is known as resultant progenies show what percent of
a) test cross tall, red flowered plants?
b) reciprocal cross a) 50%
c) dihybrid cross b) 75%
d) reverse cross c) 25%
(2003) d) 100% (2000)

69. There are three genes a , b , c. percentage of 75. A gene pair hides the effect of another gene.
crossing over between a and b is 20%, b and The phenomenon is called
c is 28% and a and c is 8%. What is the a) Dominance
sequence of genes on chromosome? b) Segregation
a) b , a , c c) Epistasis
b) a , b , c d) Mutation (1999)
c) a , c , b
d) None of these 76. If Mendel had studied the seven traits using a
(2002) plant with 12 chromosomes instead of 14, in
what way would his interpretation have been
70. Two non-allelic genes produces the new different?
phenotype when present together but fail to a) He would not have discovered the law of
do so independently then it is called independent assortment.
a) epistasis b) He would have discovered sex linkage.
b) polygene c) He could have mapped the chromosome.
 d) He would have discovered blending or c) AaBb × AaBb
incomplete dominance d) Aabb × AaBB (1993)
(1998)
83. Two dominant nonallelic genes are 50 map
77. Crossing over in diploid organism is units apart. The linkage is
responsible for a) Cis type
a) segregation of alleles b) Trans type
b) recombination of linked alleles c) Complete
c) dominance of gene d) Absent/incomplete
d) linkage between genes. (1993)
(1998)
84. Mendel studied inheritance of seven pairs of
78. A fruit fly is heterozygous for sex-linked traits in pea which can have 21 possible
genes, when mated with normal female fruit combinations. If you are told that in one of
fly, the males specific chromosome will enter these combinations, independent assortment
egg cell in the proportion is not observed in later studies, your reaction
a) 3 : 1 will be
b) 7 : 1 a) independent assortment principle may
c) 1 : 1 be wrong
d) 2 : 1 b) Mendel might not have studied all the
(1997) combinations
c) it is impossible
79. When two dominant independently assorting d) later studies may be wrong.
genes react with each other, they are called (1993)
a) collaborative genes
b) complementary genes 85. In a cross between AABB × aabb, the ratio of
c) duplicate genes F2 genotypes between AABB, AaBB, Aabb and
d) supplementary genes aabb would be
(1996) a) 9 : 3 : 3 : 1
b) 2 : 1 : 1 : 2
80. When two genetic loci produce identical c) 1 : 2 : 2 : 1
phenotypes in cis and trans position, they are d) 7 : 5 : 3 : 1 (1992)
considered to be
a) multiple alleles 86. Segregation of mendelian factors (no linkage,
b) the parts of same gene no crossing over) occur during
c) pseudoalleles a) anaphase I
d) different genes b) anaphase II
(1995) c) diplotene
d) metaphase I (1992)
81. The phenomenon, in which an allele of one
gene suppresses the activity of an allele of 87. The allele which is unable to express its effect
another gene, is known as in the presence of another is called
a) epistasis a) codominant
b) dominance b) supplementary
c) suppression c) complementary
d) inactivation (1995) d) recessive (1991)

82. Which of the following is suitable for 88. Cross between AaBB and aaBB will form
experiment on linkage? a) 1AaBB : 1aaBB
a) aaBB × aaBB b) all AaBB
b) AABB × aabb c) 3AaBB : 1aaBB
 d) 1AaBB : 3aaBB (1990) a) (ii), (iii) and (v)
b) (i), (ii) and (iii)
89. In a genetic cross having recessive epistasis, c) (ii), (iv) and (v)
F2 phenotypic ratio would be d) (i), (iii) and (v)
a) 9 : 6 : 1 (NEET 2018)
b) 15 : 1
c) 9 : 3 : 4 94. Inheritance of skin colour in humans is an
d) 12 : 3 : 1 (1990) example of
a) point mutation
90. Bateson used the terms coupling and b) polygenic inheritance
repulsion for linkage and crossing over. Name c) codominance
the correct parental of coupling type along d) chromosomal aberration
with its cross over or repulsion. (2007)
a) Coupling AABB, aabb; Repulsion AABB,
aabb 95. How many different kinds of gametes will be
b) Coupling Aabb, aaBB; Repulsion AaBb, produced by a plant having the genotype
aabb AABbCC?
c) Coupling aaBB, aabb; Repulsion AABB, a) Two
aabb b) Three
d) Coupling AABB, aabb; Repulsion Aabb, c) Four
aaBB d) Nine
(1990) (2006)

91. Segregation of Mendelian factor (Aa) occurs 96. Which one of the following is an example of
during polygenic inheritance?
a) diplotene a) Skin colour in human
b) anaphase I b) Flower colour in Mirabilis jalapa
c) zygotene/pachytene c) Production of male honeybee
d) anaphase II d) Pod shape in garden pea
(1990) (2006)

92. Two linked genes a and b show 20% 97. On selfing a plant of F1-generation with
recombination. The individuals of a dihybrid genotype “AABbCC”, the genotypic ratio in
cross between ++/++ × ab/ab shall show F2-generation will be
gametes a) 3 : 1
a) ++ : 80 : : ab : 20 b) 1 : 1
b) ++ : 50 : : ab : 50 c) 9 : 3 : 3 : 1
c) ++ : 40 : : ab : 40 : : + a : 10 : : + b : 10 d) 27 : 9 : 9 : 3 : 3 : 3 : 1 (2002)
d) ++ : 30 : : ab : 30 : : + a : 20 : : + b : 20
98. In human beings, multiple genes are involved
(1989) in the inheritance of
a) sickle-cell anaemia
POLYGENIC INHERITANCE b) skin colour
93. Which of the following characteristics c) colour blindness
represent ‘inheritance of blood groups’ in d) phenylketonuria
humans? (1999)
i) Dominance
ii) Co-dominance 99. How many different type of genetically
iii) Multiple allele different gametes will be produced by a
iv) Incomplete dominance heterozygous plant having the genotype
v) Polygenic inheritance AABbCc?
 a) Six 103. A pleiotropic gene
b) Nine a) controls a trait only in combination with
c) Two another gene
d) Four (1998) b) controls multiple traits in an individual
c) is expressed only in primitive plants
100. The polygenic genes show d) is a gene evolved during Pliocene
a) different karyotypes (2015)
b) different genotypes
c) different phenotypes 104. Which of the following is an example of
d) none of these (1996) pleiotropy?
a) Haemophilia
101. A polygenic inheritance in human beings b) Thalassemia
is c) Sickle cell anaemia
a) skin colour d) Colour blindness (2002)
b) phenylketonuria
c) colour blindness 105. When a single gene influences more than
d) sickle cell anaemia (1993) one trait it is called
a) pseudodominance
PLEIOTROPY b) pleiotropy
102. Match the terms in column I with their c) epistasis
description in column II and choose the d) none of these (1998)
correct option.
SEX DETERMINATION
Column I Column II 106. Select the incorrect statement
a) Human males have one of their sex-
A) Dominance i) Many genes govern a chromosome much shorter than other.
single character b) Male fruit fly is heterogametic
c) In male grasshoppers, 50% of sperms
B) Co- ii) In a heterozygous have no sex-chromosome
dominance organism only one allele d) In domesticated fowls, sex of progeny
expresses itself depends on the type of sperm rather
C) Pleiotropy iii) In a heterozygous than egg
organism both alleles (NEET 2019)
express themselves fully
107. Which of the following pairs is wrongly
D) Polygenic iv) A single gene matched?
inheritance influences a) Starch synthesis in pea : multiple alleles
many characters b) ABO blood grouping : co-dominance
c) XO type sex determination : Grasshopper
A B C D d) T.H. Morgan : Linkage
(NEET 2018)
a) (iv) (i) (ii) (iii)
108. Which one of the following conditions of
b) (iv) (iii) (i) (ii)
the zygotic cell would lead to the birth of a
c) (ii) (i) (iv) (iii) normal human female child?
a) Two X chromosomes
d) (ii) (iii) (iv) (i) b) Only one Y chromosome
(NEET-I 2016) c) Only one X chromosome
d) One X and one Y chromosome
(Mains 2011)
109. In Drosophila, the sex is determined by b) 1/2
a) the ratio of number of X-chromosome to c) 1/4
the sets of autosomes d) 1/8 (1993)
b) X and Y chromosomes
c) the ratio of pairs of X-chromosomes to 116. Sex is determined in human beings
the pairs of autosomes a) By ovum
d) whether the egg is fertilized or develops b) At time of fertilization
parthenogenetically (2003) c) 40 days after fertilization
d) Seventh to eight week when genitals
110. Number of Barr bodies in XXXX female is differentiate in fetus
a) 1 (1993)
b) 2
c) 3 117. A normal green male maize is crossed
d) 4 (2001) with albino female. The progeny is albino
because
111. Male XX and female XY sometime occur a) trait for a albinism is dominant
due to b) the albinos have biochemical to destroy
a) deletion plastids derived from green male
b) transfer of segments in X and Y c) plastids are inherited from female parent
chromosome d) green plastids of male must have
c) aneuploidy mutated
d) hormonal imbalance (1989)
(2001)
118. A family of five daughter only is
112. Probability of four sons to a couple is expecting sixth issue. The chance of its being
a) 1/4 a son is
b) 1/8 a) zero
c) 1/16 b) 25%
d) 1/32 c) 50%
(2001) d) 100% (1988)

113. Genetic identity of a human male is MUTATION

determined by 119. One of the parents of a cross has a
a) sex-chromosome mutation in its mitochondria. In that cross,
b) cell organelles that parent is taken as a male. During
c) autosome segregation of F2 progenies that mutation is
d) nucleolus found in
(1997) a) one-third of the progenies
b) none of the progenies
114. When an animal has both the characters c) all the progenies
of male and female, it is called d) fifty percent of the progenies.
a) super female (2004)
b) super male
c) intersex 120. The most striking example of point
d) gynandromorph mutation is found in a disease called
(1996) a) Down’s syndrome
b) sickle cell anaemia
115. Mr. Kapoor has Bb autosomal gene pair c) thalassaemia
and d allele sex-linked. What shall be d) night blindness (1995)
proportion of Bd in sperms?
a) Zero GENETIC DISORDERS
121. Select the correct match. the probability of their son being colour-blind
a) Haemophilia – Y linked is
b) Phenylketonuria – Autosomal dominant a) 0
trait b) 0.5
c) Sickle cell anaemia – Autosomal recessive c) 0.75
trait,chromosome-11 d) 1 (NEET-II 2016)
d) Thalassemia – X linked
(NEET 2020) 127. Pick out the correct statements.
1) Haemophilia is a sex-linked recessive
122. What is the genetic disorder in which an disease
individual has an overall masculine 2) Down’s syndrome is due to aneuploidy.
development, gynaecomastia and is sterile? 3) Phenylketonuria is an autosomal
a) Down’s syndrome recessive gene disorder
b) Turner’s syndrome 4) Sickle cell anaemia is an X-linked
c) Klinefelter’s syndrome recessive gene disorder.
d) Edward syndrome a) (1),(3) and (4) are correct
(NEET 2019) b) (1),(2) and (3) are correct
c) (1) and (4) are correct
123. A woman has an X-linked condition on d) (2) and (4) are correct
one of her X chromosomes. This (NEET-I 2016)
chromosome can be inherited by
a) only daughters 128. Which of the following most
b) only sons appropriately describes Haemophilia?
c) only grandchildren a) Chromosomal disorder
d) both sons and daughters b) Dominant gene disorder
(NEET 2018) c) Recessive gene disorder
d) X-linked recessive gene disorder
124. Thalassemia and sickle cell anaemia are (NEET-I 2016)
caused due to a problem in globin molecule
synthesis. Select the correct statement. 129. A colour blind man marries a woman
a) Both are due to a quantitative defect in with normal sight who has no history of
globin chain synthesis. colour blindness in her family. What is the
b) Thalassemia is due to less synthesis of probability of their grandson being colour
globin molecules. blind?
c) Sickle cell anaemia is due to a a) Nil
quantitative problem of globin b) 0.25
molecules. c) 0.5
d) Both are due to a qualitative defect in d) 1 (2015)
globin chain synthesis.
(NEET 2017) 130. In the following human pedigree, the
filled symbols represent the affected
125. A disease caused by an autosomal individuals. Identify the type of given
primary non-disjunction is pedigree.
a) Klinefelter’s syndrome
b) Turner’s syndrome
c) Sickle cell anaemia
d) Down’s syndrome.
(NEET 2017)

126. If a colour-blind man marries a woman

who is homozygous for normal colour vision,
 a) Autosomal recessive 136. Which one is the incorrect statement
b) X-linked dominant with regard to the importance of pedigree
c) Autosomal dominant analysis?
d) X-linked recessive a) It confirms that DNA is the carrier of
(2015) genetic information.
b) It helps to understand whether the trait
131. An abnormal human baby with ’XXXX’ sex in question is dominant or recessive
chromosomes was born due to c) It confirms that the trait is linked to one
a) fusion of two ova and one sperm of the autosome.
b) fusion of two sperms and one ovum d) It helps to trace the inheritance of a
c) formation of abnormal sperms in the specific trait.
father (Karnataka NEET 2013)
d) formation of abnormal ova in the mother
(2015 Cancelled) 137. Down’s syndrome in humans is due to
a) three ’X’ chromosomes
132. A man whose father was colour blind b) three copies of chromosome 21
marries a woman who had a colour blind c) monosomy
mother and normal father. What percentage d) two ‘Y’ chromosomes.
of male children of this couple will be colour (Karnataka NEET 2013)
blind?
a) 25% 138. A normal-visioned man whose father was
b) 0% colour-blind, marries a woman whose father
c) 50% was also colour-blind. They have their first
d) 75% child as a daughter. What are the chances
(2014) that this child would be colour-blind?
a) 100%
133. A human female with Turner’s syndrome b) Zero percent
a) has 45 chromosomes with XO c) 25%
b) has one additional X chromosome d) 50% (2012)
c) exhibits male characters
d) is able to produce children with normal 139. Represented here is the inheritance
husband pattern of a certain type of trait in humans.
(2014) Which one of the following conditions could
be an example of this pattern?
134. Select the incorrect statement with
regard to haemophilia.
a) It is a dominant disease.
b) A single protein involved in the clotting
of blood is affected.
c) It is a sex-linked disease.
d) It is a recessive disease
(NEET 2013) a) Phenylketonuria
b) Sickle cell anaemia
135. If both parents are carriers for c) Haemophilia
thalassaemia, which is an autosomal d) Thalassemia
recessive disorder, what are the chances of (Mains 2012)
pregnancy resulting in an affected child?
a) 25% 140. Which one of the following conditions
b) 100% correctly describes the manner of
c) No chance determining the sex?
d) 50% (NEET 2013)
 a) Homozygous sex chromosomes (ZZ) 144. Sickle-cell anaemia is
determine female sex in birds a) Caused by substitution of valine by
b) XO type of sex chromosomes determine glutamic acid in the beta globin chain of
male sex in grasshopper. haemoglobin
c) XO condition in humans as found in b) Caused by a change in a single base pair
Turner’s syndrome, determines female of DNA
sex. c) Characterized by elongated sickle like
d) Homozygous sex chromosomes (XX) RBCs with a nucleus
produce male in Drosophila d) An autosomal linked dominant trait.
(2011) (2009)

141. Which one of the following symbols and 145. Study the pedigree chart given below.
its representation, used in human pedigree What does it show?
analysis is correct?

(2010)

142. Study the pedigree chart of a certain a) Inheritance of a condition like

family given below and select the correct phenylketonuria as an autosomal
conclusion which can be drawn for the recessive in trait
character. b) The pedigree chart is wrong as this is not
possible.
c) Inheritance of a recessive sex-linked
disease like haemophilia.
d) Inheritance of a sex-linked inborn error
of metabolism like phenylketonuria
(2009)

a) The female parent is heterozygous. 146. Which one of the following conditions in
b) The parents could not have had a normal humans is correctly matched with its
daughter for this character chromosomal abnormality/linkage?
c) The trait under study could not be colour a) Erythroblastosis fetalis – X-linked
blindness b) Down’s syndrome – 44 autosomes + XO
d) The male parent is homozygous c) Klinefelter’s syndrome – 44 autosomes +
dominant. XXY
(Mains 2010) d) Colour blindness – Y-linked
(2008)
143. Select the incorrect statement from the 147. Both sickle cell anaemia and
following. Huntington’s chorea are
a) galactosemia is an inborn error of a) virus-related diseases
metabolism b) Bacteria-related diseases
b) Small population size results in random c) Congenital disorders
genetic drift in a population. d) Pollutant-induced disorders.
c) Baldness is a sex-limited trait (2006)
d) Linkage is an exception to the principle of
independent assortment in heredity. 148. If a colour blind woman marries a normal
(2009) visioned man, their sons will be
 a) All colour blind 153. Haemophilia is more commonly seen in
b) All normal visioned human males than in human females
c) One-half colour blind and one-half because
normal a) A greater proportion of girls die in
d) Three-fourths colour blind and one- infancy
fourth normal. b) This disease is due to a Y-linked recessive
(2006) mutation
c) This disease is due to an X-linked
149. Cri-du-chat syndrome in humans is recessive mutation
caused by the d) This disease is due to an X-linked
a) Trisomy of 21st chromosome dominant mutation
b) Fertilisation of an XX egg by a normal Y- (2005)
bearing sperm
c) Loss of half of the short arm of 154. Which of the following is not a hereditary
chromosome 5 disease?
d) Loss of half of the long arm of a) Cystic fibrosis
chromosome 5 b) Thalassaemia
(2006) c) Haemophilia
d) Cretinism (2005)
150. Sickle cell anaemia has not been
eliminated from the African population 155. A woman with normal vision, but whose
because father was colour blind, marries a colour
a) It is controlled by dominant genes blind man. Suppose that the fourth child of
b) It is controlled by recessive genes this couple was a boy. This boy
c) It is not a fatal disease a) May be colour blind or may be of normal
d) It provides immunity against malaria vision
(2006) b) Must be colour blind
c) Must have normal colour vision
151. A man and a women, who do not show d) Will be partially colour blind since he is
any apparent signs of a certain inherited heterozygous for the colour blind mutant
disease, have seven children (2 daughters allele.
and 5 sons). Three of the sons suffer from the (2005)
given disease but none of the daughters
affected. Which of the following mode of 156. A male human is heterozygous for
inheritance do you suggest for this disease? autosomal genes A and B and is also
a) Sex-linked dominant hemizygous for haemophilic gene h. what
b) Sex-linked recessive proportion of his sperms will be abh?
c) Sex-limited recessive a) 1/3
d) Autosomal dominant b) 1/32
(2005) c) 1/16
d) ¼ (2004)
152. A woman with 47 chromosomes due to
three copies of chromosome 21 is 157. A normal woman, whose father was
characterised by colour-blind is married to a normal man. The
a) Superfemaleness sons would be
b) Triploidy a) 75% colour-blind
c) Turner’s syndrome b) 50% colour-blind
d) Down’s syndrome c) All normal
(2005) d) All colour blind
(2004)
158. The recessive genes located on X- a) Down’s syndrome – 21st chromosome
chromosome humans are always b) Sickle cell anaemia – X-chromosome
a) Lethal c) Haemophilia – Y-chromosome
b) Sub-lethal d) Parkinson’s disease – X and Y
c) Expressed in males chromosome
d) Expressed in females (2002)
(2004) 165. Sickle cell anaemia induce to
a) Change of amino acid in ∝-chain of
159. Pattern baldness, moustaches and beard haemoglobin
in human males are examples of b) Change of amino acid in 𝛽-chain of
a) Sex linked traits haemoglobin
b) Sex limited traits c) Change of amino acid in both ∝ and 𝛽
c) Sex influenced traits chains of haemoglobin
d) Sex determining traits (2003) d) Change of amino acid either ∝ or 𝛽
chains of haemoglobin
160. Which one of the following conditions (2001)
though harmful in itself, is also potential
saviour from a mosquito borne infectious 166. Mongolian Idiocy due to trisomy in 21st
disease? chromosome is called
a) Thalassaemia a) Down’s syndrome
b) Sickle cell anaemia b) Turner’s syndrome
c) Pernicious anaemia c) Klinefelter’s syndrome
d) Leukaemia (2003) d) Triple X syndrome (2000)

161. Down’s syndrome is caused by an extra 167. In Drosophila, the XXY condition leads to
copy of chromosome number 21. what femaleness whereas in human beings the
percentage of offspring produced by an same condition leads to Klinefelter’s
affected mother and a normal father would syndrome in male. It proves
be affected by this disorder? a) In human beings Y chromosome is active
a) 100% in sex determination
b) 75% b) Y chromosome is active in sex
c) 50% determination in both human beings and
d) 25% (2003) Drosophila
c) In Drosophila Y chromosome decides
162. Christmas disease is another name for femaleness
a) Haemophilia B d) Y chromosome of man have genes for
b) Hepatitis B syndrome (2000)
c) Down’s syndrome
d) Sleeping sickness (2003) 168. A marriage between normal visioned
man and colour blind woman will produce
163. A diseased man marries a normal offspring
woman. They get three daughters and five a) Colour blind sons and 50% carrier
sons. All the daughters were diseased and daughter
sons were normal. The gene of this disease is b) 50% colour blind sons and 50% carrier
a) Sex linked dominant daughter
b) Sex linked recessive c) Normal males and carrier daughters
c) Sex limited character d) Colour blind sons and carrier daughters.
d) Autosomal dominant (2002) (1999)

164. Which of the following is a correct 169. Haemophilic man marries a normal
match? woman. Their offspring will be
 a) All haemophilic d) Haemophilia (1996)
b) All boys haemophilic
c) All girls haemophilic 175. A person whose father is colour blind
d) All normal (1999) marries a lady whose mother is daughter of a
colour blind man. Their children will be
170. A woman with two genes for a) All sons colour blind
haemophilia and one gene for colour b) Some sons normal and some colour blind
blindness on one of the ‘X’ chromosomes c) All colour blind
marries a normal man. How will the progeny d) All daughters normal
be? (1996)
a) 50% haemophilic colour-blind sons and
50% normal sons. 176. A genetically diseased father (male)
b) 50% haemophilic daughters(carrier) and marries with a normal female and gives birth
50% colour blind daughter (carrier). to 3 carrier girls and 5 normal sons. It may be
c) All sons and daughters haemophilic and which type of genetic disease?
colour blind. a) sex-influenced disease
d) Haemophilic and colour-blind daughters b) Blood group inheritance disease
(1998) c) Sex-linked disease
d) Sex-recessive (1996)
171. Mental retardation in man, associated
with sex chromosomal abnormality is usually 177. An abnormal human male phenotype
due to involving an extra X-chromosome (XXY) is a
a) Moderate increase in Y complement case of
b) Large increase in Y complement a) Edward’s syndrome
c) Reduction in X complement b) Klinefelter’s syndrome
d) Increase in X complement c) Intersex
(1998) d) Down’s syndrome (1995)

172. Albinism is known to be due to an 178. The genes which remain confined to
autosomal recessive mutation. The first child differential region of Y-chromosome, are
of a couple with normal skin pigmentation a) Autosomal genes
was an albino. What is the probability that b) Holandric genes
their second child will also be an albino? c) Completely sex-linked genes
a) 50% d) Mutant genes (1994)
b) 75%
c) 100% 179. Albinism is a congenital disorder resulting
d) 25% (1998) from the lack of which enzyme?
a) Tyrosinase
173. A person with the sex chromosomes XXY b) Xanthine oxidase
suffers from c) Catalase
a) Gynandromorphism d) Fructokinase (1994)
b) Klinefelter’s syndrome
c) Down’s syndrome 180. The colour blindness is more likely to
d) Turner’s syndrome occur in males than in females because
(1997) a) The Y-chromosome of males have the
genes for distinguishing colours
174. In which of the following diseases, the b) Genes for characters are located on the
man has an extra X-chromosome? sex-chromosomes
a) Turner’s syndrome c) The trait is dominant in males and
b) Klinefelter’s syndrome recessive in females
c) Down’s Syndrome d) None of these (1994)
181. Of both normal parents, the chances of a d) Parents have normal vision but grand
male child becoming colour blind are parents were colour blind
a) None (1991)
b) Possible only when all the four grand
parents had normal vision 187. In Down’s syndrome of a male child, the
c) Possible only when father’s mother was sex complement is
colour blind a) XO
d) Possible only when mother’s father was b) XY
colour blind c) XX
(1993) d) XXY (1990)

182. Of a normal couple, half the sons are 188. Haemophilia is more common in males
haemophiliac while half the daughters are because it is a
carries. The gene is located on a) Recessive character carried by Y-
a) X–chromosome of father chromosome
b) Y–chromosome of father b) Dominant character carried by Y-
c) One X-chromosome of mother chromosome
d) Both the X-chromosomes of mother c) Dominant trait carried by X-chromosome
(1993) d) Recessive trait carried by X-chromosome
(1990)
183. A colour blind mother and normal father
would have 189. Which one is a hereditary disease?
a) Colour blind sons and normal/carrier a) Cataract
daughters b) Leprosy
b) Colour blind sons and daughters c) Blindness
c) All colour blind d) Phenylketonuria
d) All normal (1992) (1990)

184. Down’s syndrome is due to 190. Both husband and wife have normal
a) Crossing over vision though their fathers were colour blind.
b) Linkage The probability of their daughter becoming
c) Sex-linked inheritance colour blind is
d) Non-disjunction of chromosomes a) 0%
(1992) b) 25%
c) 50%
185. In human beings 45 chromosomes/single d) 75% (1990)
X/XO abnormality cause
a) Down’s syndrome
b) Kinefelter’s syndrome
c) Turner’s syndrome
d) Edward’s syndrome (1992)

186. A colour blind girl is rare because she will

be born only when
a) Her mother and maternal grand father
were colour blind
b) Her father and maternal grand father
were colour blind
c) Her mother is colour blind and father has
normal vision
 2024 2023 2022
(1) 2 (1) 1
(1) 3
(2) 2 (2) 2
(2) 2
(3) 2 (3) 3
(3) 2
(4) 4 (4) 4
(4) 3
(5) 1 (5) 4
(5) 1
(6) (6)
(6)
(7) (7)
(7)
(8) (8)
(8)
(9) (9)
(9)
(10) (10)
(10)

(1) c (11) d (21) c (31) c (41) a (51) c (61) a (71) b (81) a (91) b
(2) a (12) d (22) b (32) d (42) d (52) d (62) d (72) d (82) b (92) c
(3) d (13) c (23) d (33) c (43) d (53) d (63) d (73) b (83) d (93) b
(4) d (14) a (24) a (34) d (44) d (54) d (64) a (74) a (84) b (94) b
(5) b (15) b (25) c (35) a (45) b (55) c (65) c (75) c (85) c (95) a
(6) b (16) c (26) c (36) a (46) c (56) a (66) b (76) a (86) a (96) a
(7) d (17) b (27) a (37) a (47) a (57) c (67) c (77) b (87) d (97) a
(8) d (18) a (28) c (38) c (48) b (58) a (68) b (78) c (88) a (98) b
(9) b (19) a (29) c (39) c (49) c (59) b (69) a (79) b (89) c (99) d
(10) d (20) a (30) c (40) d (50) b (60) d (70) a (80) c (90) d (100) c

(101) a (111) b (121) c (131) d (141) a (151) b (161) c (171) d (181) d

(102) d (112) c (122) c (132) c (142) a (152) d (162) a (172) d (182) c
(103) b (113) a (123) d (133) a (143) c (153) c (163) a (173) b (183) a
(104) c (114) d (124) b (134) a (144) b (154) d (164) a (174) b (184) d
(105) b (115) c (125) d (135) a (145) a (155) a (165) b (175) d (185) c
(106) d (116) b (126) a (136) a (146) c (156) a (166) a (176) c (186) b
(107) a (117) c (127) b (137) b (147) c (157) b (167) a (177) b (187) b
(108) a (118) c (128) d (138) b (148) a (158) c (168) d (178) b (188) d
(109) c (119) b (129) b (139) c (149) c (159) c (169) d (179) a (189) d
(110) c (120) b (130) a (140) b (150) d (160) b (170) b (180) b (190) a