Scribd
Upload
4 views20 pages

Amines and Diazonium Salt ReC

The document discusses the properties and reactions of amines, including their basicity and nucleophilic behavior. It highlights various reactions involving amines, such as protonation, substitution, and coupling reactions, along with their stability and reactivity under different conditions. Additionally, it mentions specific reactions with acids and the formation of salts, emphasizing the importance of structural factors in determining amine reactivity.

Uploaded by

basitlatf
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF or read online on Scribd
4 views20 pages

Amines and Diazonium Salt ReC

The document discusses the properties and reactions of amines, including their basicity and nucleophilic behavior. It highlights various reactions involving amines, such as protonation, substitution, and coupling reactions, along with their stability and reactivity under different conditions. Additionally, it mentions specific reactions with acids and the formation of salts, emphasizing the importance of structural factors in determining amine reactivity.

Uploaded by

basitlatf
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF or read online on Scribd
You are on page 1/ 20
Fe_ofawie levitate. of amine (WMHs) 4—N—H u—N—® _@-N-®__@=N-@ i ih ' . 4 Arnie. 2) bomine z 3 Drive . > Niktsen ote Ins a mnon-bonotol c= bait |e —NéR ri ost “Ds ro) nucleophile (donate © fo eolpriceut) L galt 4 + —~ RNA, + € ———> @-my,—& fracko Bhilte Amamovium salt nit fout oliffeet qeups shens optical aetinty f f Re Merron. @ N. hi “ea Nie & a > of not Suber arin image of cath This Compound)” is _pptieally achive « e_bmicsbtemlls of drwnines _oefeuch afew: 1) Elec, icles on, Aibiogen - ff with Aarti Celebong alovabivg f attached fie’ at Aowadius, “t ith Aun Electron pala t ley Tucenses «> More Basic qiop i attached «. donathog teuctene of ontye dletYease, «ye esid). 2) Entei of Protonation: — [Aeprt on ¢° acceptors Concibioi) 9 fee tke: 3 wits Cm wth fen by Yroups a I, ak @ 0 eto Oteepioy ESS Decreases. oo ne (om ay Protoua’ we. ) Qisfane + aap spa mnie clifficult for Arrive e Prat ; Ye Combate besisity : a* jeter blot sbi Thou oy 8: Ni Cigna ft | Beack "e= ichwt. at * WA (Us), N(Ca)e 2° [sot bore (cr " dos 3+ effect zr te {esa Sabin of moe ona lability og. States Ato check Proto ne tio + due bo & FupPing Anppens._ 4: ce ps Awine Ch. tam sR —N \ tft > 6 MH, Moles) , HA), EE, [umbrella effect] Geonssrsot Si dow fly Jiuio cis “tio | fay aon br sale +3" 2" SW Sout! jubi_Yo we polit vyaha Oy fey eich ns. Subp Mwvi_ thi. Hee ee lie“ Gavel _auvi © ogueauns (Crp. ockr) 2°) 3° >S>WvK, eo det of fail 22M, (expevianetol } jn he of Mela B2: a CH — CH, —Mbr ) CH, = CH — Mh QO CH= C—Nho e ? e > ? As 7 fe Elechowenativty fee. eton Loe tee 2 I” te dwiine with — Eleé von” With drawing guoup hence des it Basie Stew th (im wh ae S Hee due fo ¢rsowouce lone puiy ef ate ol avai Liable for _cluvatlow st Basie Stiewth es- Q is Heve (owe pai es 2 GYaliable for Aovation "Basie SLrenaih tes: oy ‘Oo 7H 4 * (No _Yesovawte) Resovewe (Beqnaee ) . * (Avowatic) But tou, C> BA Ye Atomic Amives: ry nt X= ENG ot ED6 ortho derivatives ae _sbost_bisie. oe {os SIP: Stevie Suhibition im Prolomntion. NBs (i At My NOs OmCmCtC te, (Reso) otto , (wid dan wr a7 CP A>b Ma Nie Ne Wy wy AL $: @) ° ° . {ort (a) tty (uo, +t d >c>a>pb 6 : &, go. a>d >c >b Nh om tr sai) (et ian) Nt na a “1>4M ¢ ©) oy Walogeus -1> 4H oma _|-1>-He br oe Oh ‘ One (es, et) No_ hyper conjugation on edo positions 2 Tudud bie, ech. 2 Noe +t Moe alevatig ty (yn) by, G0), 1a") 61.2») mad 44, Wl) uy Coun pave + mote — Basic wie. (om) ,4+7). * Of Wpercaujgation ot Pat fesition. 8&4 S (rte) wr Nhe Nhs OOO oytho, 1 dn toe of (ome) (em) a>t>d Sb nokmal Aug yy d>3>2.] XX: Exception onai (orto Z Paria). Birie strewsth + 2>d (ae Cdnanke sat), excep ton YrPL>r2>3 Paya S Avilive> oMltgs wea as by has om $s O g QO bu : hee omer ava ability of * st L to wh eronbh 4 reuley otey . ‘ vio » >| 4 a Shows SAS Noy oN, (sz8) r Mo, ay L> 27 >>4 (fu. at &. pind — wh Ss Oy —l— Nh > ©) Ci, — My (Guanaoline) We swe_o| tiie best 6yyaute base Sar wt 1 . Y Oh —"C — Nhe Oh, — Mm, int Mi — hy ? Ms ? vo Canal Tati a > J) Reaction with HNO, (Wittous Act ) oe. + HNO, is rienk _, Unstable _aciol_, formedl by teaction of avo, _ til Seq dul Like. el + NaN6, + Het ———> ino. + acl [t-o—N=0}) + Hr, + fel ——4 5 }.N=0. + (6 ——» N=0 + tho 4 H-o= f Nittosoniuw) me) NSO <> V=d ) (2) (Stabilly) 2 em _ smote. Cletiowesative is highly _amstable but__farsl hehe “fo check ‘octet Rule- whidh here shay Va Ot bas Complete, octet = omore stable bets a, & Gud for Porlicipation for tern Bhs to Conwrt iho As re Neot <> ‘N=0 DL Amine Ging olisonium salt + 4 4 q Ve rr Rs P—n\ Woo > R—N—N=d | 4 en a 4 & Hol v + Rowe w-G4 ———> R-NEN > (gwen) 4 tho | (Bi RANZL). Ce ten) 01° Ye gtdmine _ Ging Liber marm _ nilvossawine_testt 5 7 i “Ht 7 ow + No > e-N—Mo > [poteNao Rg g g (nitwzoamine) e g yet Amine an a HNO, [eh | Wel eel we ain Timgiowa sna trio _yeoctions be f) Substitution teen co Sad) anever reacting, CX Ff blow bevagn re Possible flew Ditspiatewn Salt Reation with Hafo, + ° + MPO W (Beis ign as has eid Com we Kaew P yo” \WH nufvilze > Hors ite Hewes > And do wot Hare Con sehoase any M_ diac ates to P { ) Ht net aged h,Po, ke Les basis! ena hl ageiat eH dese ae) wg # oH abe Have 4 attochent to p heme alsoa xoolugiva acent ° HPO, ¢ t yo \~H H n-fackor= 1, Lees bowisiby. op. Actol eat high seducing mature. Aechuckion of Riowowtinn Sabb ~ gies mnerora( _bowene 2 Coupling 4eactions + © With _owstiey wo obvivatins 9 res Hem Y q no ¥= (te, NR, oH] oh shan “° (27 defp icrut = Presence, CW at ofthe ox Perm fpaition of clitgpnim Cation. amakes ae lectou ole fieieut pe ee > menace tedactivily . on—4 Sra = \-van ms eo [Mow & cbficaul .) Phevol ¢ Fiesprnium shoulel _eeact in slighty Maal mecliwn HL Io on - €\=m =— (\-o — << CPrsen! es) Ave tw (Ph- =~) Can attach on th Pava Pow'tton Sf PA >Ie ten Problem ih —dlaxpnivun ion re dipw 2+ (WARE) (svt ci C\-4g8 40h” —> €\—nen—oh Veree if canmot previo. Coupling teun.« © Armine and _chissoniuun __shoulol__enct in. Staily Adolic medium , Cum me, | Sf oneddiuwn amo. Aeiolle. Orin, Com't vemet with Aimpnivu Salt 4 do wt 4ive Coupling den. > Fe mane at _ para psition ip ‘pum__otcupieol then ortho m) Quen +O — OmnO- 4 artto j= ou. 2) (Hen + ofS — Ono uM, Ow Speratiow|_op 35 omives (Hine ews tase) :> © Mietite + = 1} ec, albany, 6 u tuto | 7 ~ ee * 1p, => teAmives R=. asl R-NH——S— Ph => te Amive b+ eb rO — BA 4 ct Hel, o oO rife 5 m| ee $ ° (fowie Combourcl) ° ° R . : i \ I > 2 Amines R—n + tl=S—Ph_ —> Deh —yv ° Re . . Mo fury testi. g ° > Amine: _ +h > ro Reaetioun. I Rg © (%## Teme Product Atk bhi Coutetwey amen’ bei} Dstilation CT faust. (3° 49% Arie): oo _| Filivate. Roswltee, i ie Ta. Teusdivine —_Smi-soud vs more fore of Hil. Heo substawe is 2° Ausive eo bootie bat it 4s fowie. Thus teea preoluck +: $°- Aue fey, bobs bai (gh JMeot) | te water Solute lowe kar freon © vee So Magh foree af “4-2 | ik ie fitewel outs Tout 4 Weley Sduble hu rm font dence | fUtote ni fap Hater is filtereol out. de wok forum apours. ke Say ah Soule produel Fen prcbuet of 9°. frre Ole 9°, tection lei Keaction Jo of Hosou of Ssuie oP With 07 Hfo, Sai bayatai tai to rhb 2° Ase'ne baw ta po feat a) Tin) oe be x P Aaive- Ny Eon + 180,002) one At . Ne Tae >) Gira Biia.- ed for oitction ofS Aerie 1 R-NH, eile sth LEN IKOH/CHE, — t» Jam iso Cynics (ibaa set) Ron, + CHel, + koy 45 N= + kel + Bho Reaction Torowh on Tuer anediate Called Covtevie Tyley meotiate « Mle: cel, HE to + ho cet LAS; a) a a ( Cate R-n=C 4 cuauole 9 x een ae ted fortify 3, 25 4 3 one evening: (Hoffnann — Mustarol oil reaction) \ RM, + bes sme 4) [Rowoe=s] eS et 7 Appwauce Lake Miotgonate ngs ag amustaval_ oil: 2'- Amine + " $ uy 8 chee a g e “ Ae No Prooluct Uke amustovol ail. domi st es RM Cas — RaW—cas + gch 2 R -e H* 4elasea y Amine So to bend with cl of 9, and “0 Hl 4 ax Ammo nalasic ; Mh with (Rx) gins 1° awine 4 1° Amine. wifi Rx furttey gins 2°, 3° wame 4° Salt. Rx + 24, ———> e— wa,” + Ny x 8 gli wey ——» R—W—H, (2°) e iw ey ——> a—n—e_ (3°) e Ro * _ . ® R / [ Si ] [¥ eatt) ee R These eatlons nevey Provide. a sige product . Dt ns is im excess then major pret & AY Anning Af x ig in eters fen major _prohet ie 2° 23° 00 4° sat. iis ronction i¢ alse Callao! Hefponawn durmrolusic . Rewetivity of bm x tebter the Aeaving gap better 1% Rate of seacton Rx> Rory Rely RE 2) Poneto bk _CnibyL chlor > 20 3 , 1 : | R= Mh d—=e— RNu— tel ann—c—ch fa [ei] Ri Patt — ne (wre Uke) . Owdations Addition of Oxygen ic Callec! Cicla tion . Addition of electoneyrtive element ic Calleo! _Citiola tion am o U Kk ilo t io ifive ji leo! cuiolat io nceme th Oolatton to i Age Callecl auyala tiovr. Lan, = (Cl Ran, c= my LL | ec | Cee) 6) Schotten Baymenn Reoction : utines wit — Attcl Chlotsde. Bing Awaicles 6 1 pain ot Rg ——» R-nt__¢-e ~_,_ g_w—t—e a ae > \ = 1 ono » Ye Ahwmical Propels of Aevonat ie Amines Wh ki LP ki Veja _¢ai tlhe _eurol Paver CE me Pai ltsity hodljoyai qi chet to wscuoute = = $0 Eletvophille tan Pin kon Auese _ pposittow oud also Pe a le Could _attoce ou the Awe too. => Yey_sttug Sekinkig gyup. => _Orbin Pad > t* tan alse a ou _- NH. alse ) x Yologenation +> Poliplnalogevat on _cccuys « — Bh, oy Cy te > No weed of Livuis base . 4 Ae,0. wing Piceckiva guup to Pest: _Pralogua bin (ou dupe ox Au = (to t-As} Won! Net dating Erudeucy of -Wh- ecwases _towarols _loevzpe’ becouse of fre (5) fee Palyhal genation Un, is iulibrteel WOW 7 L Only Noo balesewodtiou octuys Now ow ortho ot Pav eo M4 =z 4 == ‘ Chink -Uly by Hs, on Hs, —— Ore) poop Major “S. O Yor wv to _premu haloaena bios Aninly (So,)- cyt attods on Paya " pesit ion « MW c=0 W—e=o a bay WSO, 2 (Nitiation of wiline) + Wibwtion —equied atid. nga . + Gal, Wo, Com Owicline Awiline Awol tins dtoulol be Avosole ob hy OH ail wy ne HNO», ° ee Ne, oe = due pt). t nbn, Ni Wiva robe) CH, —e—a yt— te in eit > _ ce to", OR Kho ~ Par NOs Ne ot ivertivay- iad b = exo Major ye 2) Sulbhowation + Fivet frm Amo sulphate, on deatan furfiey heating on tig temperature - fsomer fe sulphanilie auidl « Ni, Hs HSC, wh 5 Basic nut os oe Cm “0 fF NZ YatOy2 Yad + $05, 505.4 ‘| dele S05, | Kuntley Ton ve Preparation of denies ¢ Rx @ Re \ 4 Arawnoly sis): Nis —j— R-N4 > ean ak & . o ae § ay k 2D rid “Radction. R-Cooh + NaH > R- Hy ue NS (031de) 2) Cabing canction 5 ° Rta + Nano, WR. Hy 4) Cait meme Cirnmadh — taction R-g-m + oy HOH Row, 0 8) Cedichion rathods) Q- No, Q-NH, s° Metal /ocicl Q-c=en | MY /nt R-U,—NH,. 4° |\—_—_—_——_> R-Nec Na] CHa -0K— Ui Au Hy . Roc =n —on Ro-Ch—-nwy 4 Roni Q— th, —NH, oY? D Cela, ene — RON + t+ te R=N=c=o SP > RoW + Co, sto + Haley 2) Gaba Palind Sea) + oued to_fafon 1° ene bow Dn ot t / (es) s t ott CO . me OC ; ¥ ton ° (om; + Alkyl, _lralicle Sed be onettyL i and o, 2 Ru Sines Unazvation Recdiction Aromatic oS tiles” he” os re me e & ken o a © Gade mredlan): Ne 11M > Cr oe sall Cy peclutce!. Me ty Me o abd uel Me > Oo elit tohucecl. NK o ‘ 1H -E—CHy HYeH, cH elect Sel Reduction oe Gi Hetal medion): =o — [Fe/steam) CS 2 | Zz 4-0 ’m /rma) CQ 0) Ox tase Ted Dist Halt H/o. ° N=N; = ° Reduce) g lucest: /naonyp, \ 4 4 ba frlaot) Yep (0 —N=N—( 0) mop Reduced. i 7 Ct ww > neak Aud median = - l e Nw—ol i a ‘ J <_aes l Alea live Nt ° Lol wou ve Gilectic hechetiow) 5» No Nu NOs er 5 | 4 A cy) ee GS ako [ ere Ro uel Hak typ \ Ane, de avd “KAR ne dequs. “ not _obfeud + hes x Kon 2 T Whe on nature of x Sucks +H ui ‘NO> Ayn J 7 110,

You might also like

pFad - Phonifier reborn

Pfad - The Proxy pFad of © 2024 Garber Painting. All rights reserved.

Note: This service is not intended for secure transactions such as banking, social media, email, or purchasing. Use at your own risk. We assume no liability whatsoever for broken pages.


Alternative Proxies:

Alternative Proxy

pFad Proxy

pFad v3 Proxy

pFad v4 Proxy