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Biostatisitcs and Research Methodology Syllabus Sem Viii

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29 views2 pages

Biostatisitcs and Research Methodology Syllabus Sem Viii

Uploaded by

sanu57813555
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
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BP801T.

BIOSTATISITCS AND RESEARCH METHODOLOGY


(Theory)

Unit-I

Introduction: Statistics, Biostatistics, Frequency distribution

Measures of central tendency: Mean, Median, Mode- Pharmaceutical


examples

Measures of dispersion: Dispersion, Range, standard deviation,


Pharmaceutical problems

Correlation: Definition, Karl Pearson’s coefficient of correlation, Multiple


correlation -Pharmaceuticals examples

Unit-II

Regression: Curve fitting by the method of least squares, fitting the lines y= a +
bx and x= a + by, Multiple regression, standard error of regression
Pharmaceutical Examples

Probability:Definition of probability, Binomial distribution, Normal


distribution, Poisson’s distribution, properties - problemsSample, Population,
large sample, small sample, Null hypothesis, alternative hypothesis, sampling,
essence of sampling, types of sampling, Error-I type, Error-II type, Standard
error of mean (SEM) - Pharmaceutical examples

Parametric test: t-test(Sample, Pooled or Unpaired and Paired) , ANOVA,


(One way and Two way), Least Significance difference

Unit-III

Non Parametric tests: Wilcoxon Rank Sum Test, Mann-Whitney U test,


Kruskal-Wallis test, Friedman Test

Introduction to Research: Need for research, Need for design of Experiments,


Experiential Design Technique, plagiarism

Graphs: Histogram, Pie Chart, Cubic Graph, response surface plot, Counter
Plot graph
Designing the methodology: Sample size determination and Power of a study,
Report writing and presentation of data, Protocol, Cohorts studies,
Observational studies, Experimental studies, Designing clinical trial, various
phases.

Unit-IV

Blocking and confounding system for Two-level factorials


Regression modeling: Hypothesis testing in Simple and Multiple regression
models
Introduction to Practical components of Industrial and Clinical Trials
Problems:
Statistical Analysis Using Excel, SPSS, MINITAB®, DESIGN OF
EXPERIMENTS, R -
Online Statistical Software’s to Industrial and Clinical trial approach
Unit-V

Design and Analysis of experiments:

Factorial Design: Definition, 22, 23design. Advantage of factorial design

Response Surface methodology: Central composite design, Historical design,


Optimization Techniques

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