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B PHARM
(SEM VIII) THEORY EXAMINATION 2022-23
BIOSTATISTICS AND RESEARCH METHODOLOGY
Time: 3 Hours Total Marks: 75
Note: Attempt all Sections.

SECTION A

1. Attempt all questions in brief. 10 x 2 = 20

a. Null hypothesis.
b. Define Karl Pearson’s coefficient of correlation.
c. Confidence interval.
d. Write the applications of nonparametric tests.
e. Define degrees of freedom.
f. Define one-tailed and two-tailed tests.
g. What is Plagiarism?
h. Define the Power of a study.
i. Standard error of the mean and its significance?

2
90

13
j. Report writing in the research study.
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2.
P1

24
SECTION B

5.
3D

2. Attempt any two parts of the following: 2 x 10 = 20

.5
a. Definehypothesis? What are the different types of hypothesis? Explain how you will formulate
P2

a hypothesis with a suitable example. 17

Q

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b. Explain the types and advantages of factorial design in formulation development.
6

c. Describe the different measures of central tendency. Calculate the mean and standard deviation
:0

for the given data on the mid-arm circumference(cm) of 16 children –14, 12, 13, 10, 11, 13, 14,
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12, 12, 11, 10, 13, 12, 11, 10, 14

:
13

SECTION C
3
02

3. Attempt any five parts of the following: 7 x 5 = 35

-2

a. Classify different types of data; explain any three measures of dispersion with examples.
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2-

b. Discuss the hypothesis testing of parametric data.

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c. Explain types of correlation and correlation coefficient. Give suitable examples.

d. Explain ANOVA and write its applications.
e. Define Plagiarism in Research? How to remove Plagiarism in a Research Paper?
f. What are non-parametric tests? Explain the chi-square test-Goodness of fit test.
g. Discuss the applications of EXCEL and SPSS programs in statistical analysis.

QP23DP1_290 | 12-01-2023 13:23:06 | 117.55.242.132

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Subject Code: BP801T
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BPHARM
(SEM VIII) THEORY EXAMINATION 2023-24
BIOSTATISTICS AND RESEARCH METHODOLOGY
TIME: 3 HRS M.MARKS: 75

Note: 1. Attempt all Sections. If require any missing data; then choose suitably.

SECTION A
1. Attempt all questions in brief. 10 x 2 = 20
a. Define Biostatistics.
b. Discuss the importance of median in pharmaceutical research.
c. Describe the Poisson distribution.
d. Explain the null hypothesis.
e. Describe power of study with an example.
f. Illustrate the Histogram, and Pie Chart.
g. Elaborate the term “blocking” in the context of two-level factorial designs.
h. Describe design of experiment, and its utilization to optimize clinical trials.
i. Write the significance of Cohorts studies in new drug development.
j. Summarize the benefits of using response surface methodology in pharmaceutical
research.
90

2
13
SECTION B
_2

2. Attempt any two parts of the following: 2 x 10 = 20

2.
P1

a. Analyze the different types of statistics that are commonly used in pharmacy.

24
Explain their roles in pharmaceutical research and development.
4D

5.
b. Explain various types of clinical studies and describes various phases of clinical
trials.
.5
P2

17
c. Explain mean. Write any two merits of mean. Find mean and median of the
Q

following dataset:
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Class 0-20 20-40 40-60 60-80 80-100

Frequency 17 28 32 24 19
4 9
6:

SECTION C
:3

3. Attempt any five parts of the following: 5 x 7 = 35

13

a. Calculate standard deviation of the weight of the batch of medicine for the following
data: A pharmaceutical company wants to test the purity of a new batch of medicine.
4

They take a sample of 10 pills and measure their weight in milligrams (mg). The
02

results are as follows: 37, 39, 40, 41, 42, 44, 45, 47, 50, 55
-2

b. Differentiate between Type I and Type II errors in hypothesis testing for regression
01

models. Describe the methods to control these errors.

c. Explain the Wilcoxon rank sum test, and its importance in statistical analysis.
1-

Compare how does it differ from the t-test.

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d. Illustrate the term “Plagiarism”, and why is it considered unethical in academic and
research settings.
e. Explain the application of EXCEL and SPSS programs in statistical research
analysis.
f. Describe the term “historical design.” Illustrate the steps involved in conducting a
historical Design study.
g. Discuss in detail about factorial design. Explain the role of randomization in a
factorial design.

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QP24DP1_290 | 31-01-2024 13:36:49 | 117.55.242.132
 Printed Page: 1 of 1
Subject Code: BP801T
0Roll No: 0 0 0 0 0 0 0 0 0 0 0 0 0

BPHARM
(SEM VIII) THEORY EXAMINATION 2023-24
BIOSTATISTICS AND RESEARCH METHODOLOGY
TIME: 3 HRS M.MARKS: 75

Note: 1. Attempt all Sections. If require any missing data; then choose suitably.

SECTION A
1. Attempt all questions in brief. 10 x 2 = 20
a. Write all the measures of dispersion.
b. Define Variance.
c. Discuss method of least squares.
d. What is Confidence interval?
e. Define degree of freedom.
f. Define one- tailed and Two- tailed test.
g. Explain the formulation of Null hypothesis and Alternative hypothesis.
h. How can you describe Pie chart?
i. Differentiate between un-constrained and constrained variable.
j. Define role of randomization in a factorial design.

2
16
55
SECTION B

4.
_8

2. Attempt any two parts of the following: 2 x 10 = 20

18
a. Describe the different measures of central tendency. Calculate the mean and standard
P1

8.
deviation for the given data on the mid-arm circumference(cm) of 16 children –14, 12, 13,
4E

10, 11, 13, 14, 12, 12, 11, 10, 13, 12, 11, 10, 14

.5
b. Define hypothesis. What are the different types of hypothesis? Explain how you will
52
P2

formulate a hypothesis with a suitable example.

|1
Q

c. Explain in detail about 23 factorial designs. Elaborate its merit and demerits in experimental
research.
PM

SECTION C
2

3. Attempt any five parts of the following: 7 x 5 = 35

:2

a. For the following blood pressure measurements 100,98,101,94,104,102,108,108.

35

Calculate the coefficient of range.

1:

b. Classify the different types of sampling that could be used in a study on the prevalence of a
specific disease in a population.
24

c. Using least square method fit a straight line to the following data
20

X 0 1 2 3 4
n-

Y 1 1.8 3.3 4.5 6.3

Ju

d. Discuss Blocking and confounding system in detail.

e. Explain the term “Historical design”. Illustrate the steps involved in conducting
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f. Explain the detail about Karl Pearson’s correlation utilized to analyze data in pharmaceutical
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company’s study that aims to establish the relationship between drug dosage and its
effectiveness.
g. Discuss the term “Plagiarism”. Why is it considered unethical in academic and research
settings?

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