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Biostatistics and Research Methodology-BP801T

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370 views1 page

Biostatistics and Research Methodology-BP801T

Uploaded by

mohd kaif
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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Subject Code: BP801T


0Roll No: 0 0 0 0 0 0 0 0 0 0 0 0 0

BPHARM
(SEM VIII) THEORY EXAMINATION 2023-24
BIOSTATISTICS AND RESEARCH METHODOLOGY
TIME: 3 HRS M.MARKS: 75

Note: 1. Attempt all Sections. If require any missing data; then choose suitably.

SECTION A
1. Attempt all questions in brief. 10 x 2 = 20
a. Define Biostatistics.
b. Discuss the importance of median in pharmaceutical research.
c. Describe the Poisson distribution.
d. Explain the null hypothesis.
e. Describe power of study with an example.
f. Illustrate the Histogram, and Pie Chart.
g. Elaborate the term “blocking” in the context of two-level factorial designs.
h. Describe design of experiment, and its utilization to optimize clinical trials.
i. Write the significance of Cohorts studies in new drug development.
j. Summarize the benefits of using response surface methodology in pharmaceutical
research.
90

2
13
SECTION B
_2

2. Attempt any two parts of the following: 2 x 10 = 20

2.
P1

a. Analyze the different types of statistics that are commonly used in pharmacy.

24
Explain their roles in pharmaceutical research and development.
4D

5.
b. Explain various types of clinical studies and describes various phases of clinical
trials.
.5
P2

17
c. Explain mean. Write any two merits of mean. Find mean and median of the
Q

following dataset:
|1

Class 0-20 20-40 40-60 60-80 80-100


Frequency 17 28 32 24 19
4 9
6:

SECTION C
:3

3. Attempt any five parts of the following: 5 x 7 = 35


13

a. Calculate standard deviation of the weight of the batch of medicine for the following
data: A pharmaceutical company wants to test the purity of a new batch of medicine.
4

They take a sample of 10 pills and measure their weight in milligrams (mg). The
02

results are as follows: 37, 39, 40, 41, 42, 44, 45, 47, 50, 55
-2

b. Differentiate between Type I and Type II errors in hypothesis testing for regression
01

models. Describe the methods to control these errors.


c. Explain the Wilcoxon rank sum test, and its importance in statistical analysis.
1-

Compare how does it differ from the t-test.


|3

d. Illustrate the term “Plagiarism”, and why is it considered unethical in academic and
research settings.
e. Explain the application of EXCEL and SPSS programs in statistical research
analysis.
f. Describe the term “historical design.” Illustrate the steps involved in conducting a
historical Design study.
g. Discuss in detail about factorial design. Explain the role of randomization in a
factorial design.

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